Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Decay characteristics of HIV-1-infected compartments during combination therapy

1997 • 1,849 citations

Positive Effects of Combined Antiretroviral Therapy on CD4 ⁺ T Cell Homeostasis and Function in Advanced HIV Disease

1997 • 1,812 citations

Differential Requirements for Survival and Proliferation of CD8 Naïve or Memory T Cells

1997 • 875 citations

Multifactorial Nature of Human Immunodeficiency Virus Disease: Implications for Therapy

1993 • 803 citations

Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy".

1994 • 788 citations

Qualitative Analysis of Immune Function in Patients with the Acquired Immunodeficiency Syndrome

1985 • 737 citations

The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments.

1993 • 664 citations

Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV

1994 • 611 citations

T-cell repertoire diversity and clonal expansions in normal and clinical samples

1995 • 562 citations

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

1992 • 531 citations

HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

1997 • 527 citations

The Complete 685-Kilobase DNA Sequence of the Human β T Cell Receptor Locus

1996 • 434 citations

Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease.

1993 • 427 citations

Expanded CD4+ and CD8+ T cell clones in elderly humans.

1997 • 307 citations

An experimentally validated panel of subfamily‐specific oligonucleotide primers (V_α1‐w29/V_β1‐w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction

1992 • 302 citations

Benign Monoclonal Gammapathy

1984 • 249 citations

Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

1994 • 232 citations

Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis.

1995 • 213 citations

Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset.

1995 • 162 citations

Oligoclonal expansion of CD8+ CD57+ T cells with restricted T-cell receptor beta chain variability after bone marrow transplantation

1994 • 141 citations

Influence of HLA genes on T cell receptor V segment frequencies and expression levels in peripheral blood lymphocytes.

1993 • 135 citations

Dynamics of viral variants in HIV-1 Nef and specific cytotoxic T lymphocytes in vivo.

1996 • 114 citations

Variability in T cell receptor V beta gene usage in human peripheral blood lymphocytes. Studies of identical twins, siblings, and insulin-dependent diabetes mellitus patients.

1992 • 95 citations

Carboxyl-terminal and central regions of human immunodeficiency virus-1 NEF recognized by cytotoxic T lymphocytes from lymphoid organs. An in vitro limiting dilution analysis.

1992 • 91 citations

T cell receptor (TCR) BV gene repertoires and clonal expansions of CD4 cells in patients with HIV infections

1997 • 90 citations

Factors controlling the turnover of T memory cells

1997 • 78 citations

T-cell antigen receptor Vβ subsets are not preferentially deleted in AIDS

1993 • 61 citations

Recurrent T cell receptor rearrangements in the cytotoxic T lymphocyte response in vivo against the p815 murine tumor.

1996 • 56 citations

Interdependence of N Nucleotide Addition and Recombination Site Choice in V(D)J Rearrangement

2004 • 35 citations

Interdependence of N nucleotide addition and recombination site choice in V(D)J rearrangement.

1996 • 34 citations

Few V gene segments dominate the T cell receptor beta-chain repertoire of the human thymus.

1993 • 33 citations

Lack of selective Vβ deletion in peripheral CD4⁺ T cells of human immunodeficiency virus‐infected infants

1993 • 22 citations

The Jβ segment of the T cell receptor contributes to the Vβ‐specific T cell expansion caused by staphylococcal enterotoxin B and Urtica dioica superantigens

1996 • 22 citations