Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

1996 • 1,750 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

NEUROTROPHINS AND SYNAPTIC PLASTICITY

1999 • 1,343 citations

Mechanisms and consequences of activation of protein kinase B/Akt

1998 • 1,305 citations

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

1999 • 1,255 citations

The MAPK cascade is required for mammalian associative learning

1998 • 1,086 citations

Intracellular Signaling Pathways Activated by Neuropathic Factors

1996 • 958 citations

A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity

1996 • 948 citations

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1998 • 872 citations

A BDNF autocrine loop in adult sensory neurons prevents cell death

1995 • 743 citations

Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis.

2002 • 720 citations

Initiation of Protein Synthesis in Eukaryotic Cells

1996 • 715 citations

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.

1996 • 671 citations

Brain-Derived Neurotrophic Factor Induces Long-Term Potentiation in Intact Adult Hippocampus: Requirement for ERK Activation Coupled to CREB and Upregulation ofArcSynthesis

2002 • 638 citations

Making New Connections

1999 • 601 citations

Involvement of Brain-Derived Neurotrophic Factor in Spatial Memory Formation and Maintenance in a Radial Arm Maze Test in Rats

2000 • 539 citations

A Mitogen-Activated Protein Kinase Cascade in the CA1/CA2 Subfield of the Dorsal Hippocampus Is Essential for Long-Term Spatial Memory

1999 • 520 citations

Regulation of eIF-4E BP1 Phosphorylation by mTOR

1997 • 511 citations

Role for brain-derived neurotrophic factor in learning and memory

2002 • 400 citations

A Necessity for MAP Kinase Activation in Mammalian Spatial Learning

1999 • 346 citations

Long-term potentiation: What's learning got to do with it?

1997 • 308 citations

Brain-derived Neurotrophic Factor Enhances Neuronal Translation by Activating Multiple Initiation Processes

2001 • 199 citations

Protein Phosphorylation in Translational Control

1992 • 180 citations

Signaling Mechanisms Mediating BDNF Modulation of Synaptic Plasticity in the Hippocampus

1999 • 162 citations

Long-term potentiation in dentate gyrus of the rat is inhibited by the phosphoinositide 3–kinase inhibitor, wortmannin

2000 • 147 citations

A Role of Fos Expression in the CA3 Region of the Hippocampus in Spatial Memory Formation in Rats

2002 • 128 citations

Neurotrophic Molecules: Strategies for Designing Effective Therapeutic Molecules in Neurodegeneration

1998 • 97 citations

Peptide-chain elongation in eukaryotes

1994 • 86 citations

Brain‐Derived Neurotrophic Factor Stimulates Interactions of Shp2 with Phosphatidylinositol 3‐Kinase and Grb2 in Cultured Cerebral Cortical Neurons

1999 • 34 citations