A BDNF autocrine loop in adult sensory neurons prevents cell death

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.

1978 • 1,668 citations

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

1991 • 1,487 citations

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1994 • 1,066 citations

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development

1994 • 1,046 citations

The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

1991 • 940 citations

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1991 • 887 citations

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1991 • 830 citations

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1991 • 819 citations

Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family

1990 • 817 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons

1988 • 657 citations

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

1992 • 633 citations

Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets

1994 • 581 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

1992 • 521 citations

Copurification of E. coli RNAase E and PNPase: Evidence for a specific association between two enzymes important in RNA processing and degradation

1994 • 430 citations

Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization

1990 • 365 citations

Sensory Neurons: Diversity, Development and Plasticity

1993 • 344 citations

Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF

1993 • 333 citations

Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: Inhibition by antibodies to NGF

1991 • 284 citations

Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor.

1989 • 270 citations

Coexpression of neurotrophins and their receptors in neurons of the central nervous system.

1993 • 242 citations

The role of NGF in sensory neurons in vivo

1986 • 233 citations

Sensory Neurons; Diversity, Development and Plasticity

1994 • 226 citations

The Neurotrophins BDNF, NT‐3 and NT‐4/5, But Not NGF, Up‐regulate the Cholinergic Phenotype of Developing Motor Neurons

1993 • 192 citations

Suppression of basic fibroblast growth factor expression by antisense oligodeoxynucleotides inhibits the growth of transformed human astrocytes.

1991 • 162 citations

Inhibition of vesicular stomatitis virus protein synthesis and infection by sequence-specific oligodeoxyribonucleoside methylphosphonates

1986 • 151 citations

Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons

1992 • 123 citations

Central nervous system and peripheral nerve growth factor provide trophic support critical to mature sensory neuronal survival

1985 • 118 citations

Antisense c-myc oligodeoxyribonucleotide cellular uptake.

1992 • 61 citations

Cholera Toxin and Dibutyryl Cyclic AMP Inhibit the Expression of Neurofilament Protein Induced by Nerve Growth Factor in Cultures of Naive and Primed PC12 Cells

1987 • 37 citations