The neurofibromatosis 2 protein product merlin selectively binds F-actin but not G-actin, and stabilizes the filaments through a lateral association

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Rho GTPases and their effector proteins

2000 • 1,941 citations

The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly

1999 • 1,332 citations

Rho-Kinase Phosphorylates COOH-terminal Threonines of Ezrin/Radixin/Moesin (ERM) Proteins and Regulates Their Head-to-Tail Association

1998 • 849 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

1996 • 601 citations

Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family

1997 • 582 citations

The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange

1998 • 582 citations

The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane

1998 • 530 citations

An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton

1998 • 472 citations

Cortical Actin Organization: Lessons from ERM (Ezrin/Radixin/Moesin) Proteins

1999 • 464 citations

Rho GTPases and their effector proteins

2000 • 461 citations

Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

1997 • 424 citations

Mechanisms of actin rearrangements mediating platelet activation.

1992 • 413 citations

A C-terminal motif found in the β ₂ -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na ⁺ /H ⁺ exchanger regulatory factor family of PDZ proteins

1998 • 406 citations

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family.

1994 • 395 citations

Regulation of cortical structure by the ezrin-radixin-moesin protein family

1999 • 365 citations

ERM proteins in cell adhesion and membrane dynamics

1999 • 364 citations

Peptide binding consensus of the NHE‐RF‐PDZ1 domain matches the C‐terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)

1998 • 278 citations

NHE3 Kinase A Regulatory Protein E3KARP Binds the Epithelial Brush Border Na+/H+ Exchanger NHE3 and the Cytoskeletal Protein Ezrin

1998 • 269 citations

NHE-RF, a Regulatory Cofactor for Na+-H+Exchange, Is a Common Interactor for Merlin and ERM (MERM) Proteins

1998 • 252 citations

Interdomain binding mediates tumor growth suppression by the NF2 gene product

1997 • 234 citations

The cytoskeleton of the resting human blood platelet: structure of the membrane skeleton and its attachment to actin filaments.

1991 • 233 citations

A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization.

1989 • 211 citations

Merlin differentially associates with the microtubule and actin cytoskeleton

1998 • 171 citations

Moesin, ezrin, and p205 are actin-binding proteins associated with neutrophil plasma membranes.

1995 • 169 citations

Neurofibromatosis 2 tumor suppressor protein colocalizes with ezrin and CD44 and associates with actin-containing cytoskeleton

1997 • 168 citations

Neurofibromatosis 2 tumour suppressor schwannomin interacts with βII-spectrin

1998 • 155 citations

The B1 Subunit of the H+ATPase Is a PDZ Domain-binding Protein

2000 • 150 citations

Regulation of F-Actin Binding to Platelet Moesin In Vitro by Both Phosphorylation of Threonine 558 and Polyphosphatidylinositides

1999 • 145 citations

Coordinated regulation of platelet actin filament barbed ends by gelsolin and capping protein.

1996 • 144 citations

Ezrin NH2-terminal domain inhibits the cell extension activity of the COOH-terminal domain.

1995 • 135 citations

Biochemical Characterization of Ezrin-Actin Interaction

1996 • 125 citations

Indirect association of ezrin with F-actin: isoform specificity and calcium sensitivity.

1995 • 120 citations

The merlin tumor suppressor localizes preferentially in membrane ruffles.

1996 • 116 citations

A Dual Involvement of the Amino-terminal Domain of Ezrin in F- and G-actin Binding

1997 • 112 citations

Homotypic and heterotypic interaction of the neurofibromatosis 2 tumor suppressor protein merlin and the ERM protein ezrin

1999 • 108 citations

Molecular dissection of radixin: distinct and interdependent functions of the amino- and carboxy-terminal domains.

1995 • 106 citations

Merlin: the neurofibromatosis 2 tumor suppressor

1999 • 101 citations

Interdomain Interaction of Merlin Isoforms and Its Influence on Intermolecular Binding to NHE-RF

1999 • 89 citations

Expression level, subcellular distribution and Rho-GDI binding affinity of merlin in comparison with ezrin/radixin/moesin proteins

1999 • 86 citations

Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease-Causing Point Mutations

2000 • 64 citations

Three determinants in ezrin are responsible for cell extension activity.

1997 • 63 citations

Impaired interaction of naturally occurring mutant NF2 protein with actin-based cytoskeleton and membrane

1998 • 59 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 53 citations

Basolateral Na+/HCO3– cotransport activity is regulated by the dissociable Na+/H+ exchanger regulatory factor

1999 • 48 citations

Merlin Differs from Moesin in Binding to F-Actin and in Its Intra- and Intermolecular Interactions

1998 • 47 citations

The product of the NF2 tumour suppressor gene localizes near the plasma membrane and is highly expressed in muscle cells.

1995 • 43 citations

Analysis of Molecular Domains of Epitope-Tagged Merlin Isoforms in Cos-7 Cells and Primary Rat Schwann Cells

1998 • 37 citations