Three determinants in ezrin are responsible for cell extension activity.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

1993 • 1,376 citations

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

1993 • 1,360 citations

[18] Purification of muscle actin

1982 • 1,186 citations

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

1994 • 790 citations

FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas

1995 • 702 citations

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

1996 • 601 citations

Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker.

1993 • 427 citations

Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells

1993 • 426 citations

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site.

1995 • 422 citations

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family.

1994 • 395 citations

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

1989 • 385 citations

A method for producing recombinant baculovirus expression vectors at high frequency.

1993 • 348 citations

Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members.

1994 • 347 citations

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

1997 • 309 citations

Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells.

1983 • 294 citations

cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1.

1989 • 253 citations

Moesin: a member of the protein 4.1-talin-ezrin family of proteins.

1991 • 250 citations

ICAM-2 redistributed by ezrin as a target for killer cells

1996 • 233 citations

Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types

1994 • 228 citations

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift.

1995 • 216 citations

Ezrin oligomers are major cytoskeletal components of placental microvilli: a proposal for their involvement in cortical morphogenesis.

1995 • 208 citations

Molecular cloning of protein 4.1, a major structural element of the human erythrocyte membrane skeleton.

1986 • 205 citations

Phosphorylation of Threonine 558 in the Carboxyl-terminal Actin-binding Domain of Moesin by Thrombin Activation of Human Platelets

1995 • 205 citations

Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin.

1991 • 203 citations

Identification of a phosphatidylinositol‐4,5‐bisphosphate‐binding domain in the N‐terminal region of ezrin

1995 • 198 citations

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.

1991 • 198 citations

Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin.

1992 • 189 citations

Membrane-actin microfilament connections: an increasing diversity of players related to band 4.1

1994 • 183 citations

The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilli.

1991 • 182 citations

Submembranous junctional plaque proteins include potential tumor suppressor molecules.

1993 • 179 citations

The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.

1986 • 173 citations

Moesin, ezrin, and p205 are actin-binding proteins associated with neutrophil plasma membranes.

1995 • 169 citations

Radixin is a novel member of the band 4.1 family.

1991 • 167 citations

Efficient site-directed mutagenesis by simultaneous use of two primers

1983 • 154 citations

Distinct cellular and subcellular patterns of expression imply distinct functions for the Drosophila homologues of moesin and the neurofibromatosis 2 tumor suppressor, merlin.

1996 • 153 citations

Ezrin Becomes Restricted to Outer Cells Following Asymmetrical Division in the Preimplantation Mouse Embryo

1996 • 152 citations

Concentration of an integral membrane protein, CD43 (leukosialin, sialophorin), in the cleavage furrow through the interaction of its cytoplasmic domain with actin-based cytoskeletons.

1993 • 148 citations

Subcellular Localization of Moesin in Dynamic Filopodia, Retraction Fibers, and Other Structures Involved in Substrate Exploration, Attachment, and Cell-Cell Contacts

1995 • 147 citations

Radixin, a barbed end-capping actin-modulating protein, is concentrated at the cleavage furrow during cytokinesis [published erratum appears in J Cell Biol 1991 Sep;114(5):1101-3]

1991 • 147 citations

Moesin, like ezrin, colocalizes with actin in the cortical cytoskeleton in cultured cells, but its expression is more variable

1993 • 135 citations

Ezrin NH2-terminal domain inhibits the cell extension activity of the COOH-terminal domain.

1995 • 135 citations

Ezrin has properties to self-associate at the plasma membrane

1994 • 133 citations

The merlin tumor suppressor localizes preferentially in membrane ruffles.

1996 • 116 citations

Structural diversity of band 4.1 superfamily members

1994 • 113 citations

The role of cytoskeleton in organizing growth cones: a microfilament-associated growth cone component depends upon microtubules for its localization.

1989 • 108 citations

Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injury.

1995 • 107 citations

Heterotypic and homotypic associations between ezrin and moesin, two putative membrane-cytoskeletal linking proteins.

1993 • 107 citations

Molecular dissection of radixin: distinct and interdependent functions of the amino- and carboxy-terminal domains.

1995 • 106 citations

Interdomain Interactions of Radixin in Vitro

1995 • 93 citations

Cytovillin, a Microvillar Mr 75,000 Protein

1989 • 92 citations

A novel protein-tyrosine phosphatase with homology to both the cytoskeletal proteins of the band 4.1 family and junction-associated guanylate kinases.

1994 • 91 citations

Soluble ezrin purified from placenta exists as stable monomers and elongated dimers with masked C-terminal ezrin-radixin-moesin association domains

1995 • 87 citations

Src kinase associates with a member of a distinct subfamily of protein-tyrosine phosphatases containing an ezrin-like domain.

1994 • 83 citations

Characterization of an 80-kDa phosphoprotein involved in parietal cell stimulation

1989 • 80 citations

Physical association of moesin and CD46 as a receptor complex for measles virus

1995 • 80 citations

Microtubule associated protein MAP1A is an actin‐binding and crosslinking protein

1994 • 69 citations

Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast.

1994 • 66 citations

Induction of Tyrosine Phosphorylation and Translocation of Ezrin by Hepatocyte Growth Factor/Scatter Factor (HGF/SF)

1995 • 66 citations

Differential expression of the microspike-associated protein moesin in human tissues.

1995 • 64 citations

Microfilaments and membranes

1993 • 53 citations

Pez - A Novel Human cDNA Encoding Protein Tyrosine Phosphatase- and Ezrin-Like Domains

1995 • 52 citations

Association of ezrin isoforms with the neuronal cytoskeleton

1991 • 44 citations

The product of the NF2 tumour suppressor gene localizes near the plasma membrane and is highly expressed in muscle cells.

1995 • 43 citations

Enhanced expression of multiple protein tyrosine phosphatases in the regenerating mouse liver: isolation of PTP-RL10, a novel cytoplasmic-type phosphatase with sequence homology to cytoskeletal protein 4.1.

1995 • 27 citations

Cloning and sequencing of porcine moesin and radixin cDNA and identification of highly conserved domains

1993 • 26 citations

Identification of a novel protein tyrosine phosphatase with sequence homology to the cytoskeletal proteins of the band 4.1 family

1994 • 18 citations