Impaired interaction of naturally occurring mutant NF2 protein with actin-based cytoskeleton and membrane

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

1993 • 1,376 citations

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

1993 • 1,360 citations

A TECHNIQUE FOR ULTRACRYOTOMY OF CELL SUSPENSIONS AND TISSUES

1973 • 1,057 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

1994 • 790 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

A Clinical Study of Type 2 Neurofibromatosis

1992 • 628 citations

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

1996 • 601 citations

Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linker.

1993 • 427 citations

Antibodies to the Golgi complex and the rough endoplasmic reticulum.

1982 • 418 citations

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family.

1994 • 395 citations

High frequency of inactivating mutations in the neurofibromatosis type 2 gene (NF2) in primary malignant mesotheliomas.

1995 • 344 citations

A gene family consisting of ezrin, radixin and moesin Its specific localization at actin filament/plasma membrane association sites

1992 • 334 citations

Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer

1995 • 296 citations

Structural features of the cell surface receptor for transferrin that is recognized by the monoclonal antibody OKT9.

1982 • 275 citations

A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin.

1991 • 257 citations

Type of mutation in the neurofibromatosis type 2 gene (NF2) frequently determines severity of disease.

1996 • 241 citations

ICAM-2 redistributed by ezrin as a target for killer cells

1996 • 233 citations

Stepwise reassembly of the nuclear envelope at the end of mitosis

1993 • 220 citations

[37] Immunoelectron microscopy using thin, frozen sections: Application to studies of the intracellular transport of Semliki Forest virus spike glycoproteins

1983 • 212 citations

Germ-line mutations in the neurofibromatosis 2 gene: correlations with disease severity and retinal abnormalities.

1996 • 207 citations

Exon scanning for mutation of the NF2 gene in schwannomas

1994 • 188 citations

Membrane-actin microfilament connections: an increasing diversity of players related to band 4.1

1994 • 183 citations

Moesin, ezrin, and p205 are actin-binding proteins associated with neutrophil plasma membranes.

1995 • 169 citations

An anti-Ras function of neurofibromatosis type 2 gene product (NF2/Merlin).

1994 • 153 citations

Concentration of an integral membrane protein, CD43 (leukosialin, sialophorin), in the cleavage furrow through the interaction of its cytoplasmic domain with actin-based cytoskeletons.

1993 • 148 citations

Golgi apparatus in chick skeletal muscle: changes in its distribution during end plate development and after denervation.

1989 • 140 citations

Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas

1995 • 135 citations

Screening for germ‐line mutations in the NF2 Gene

1995 • 127 citations

Identification of NF2 germ-line mutations and comparison with neurofibromatosis 2 phenotypes

1996 • 124 citations

The merlin tumor suppressor localizes preferentially in membrane ruffles.

1996 • 116 citations

Mutational analysis of patients with neurofibromatosis 2.

1994 • 116 citations

Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers

1994 • 101 citations

The neurofibromatosis type 2 gene product, schwannomin, suppresses growth of NIH 3T3 cells.

1995 • 99 citations

Expression of the neurofibromatosis 2 tumor suppressor gene product, merlin, in Schwann cells

1996 • 76 citations

DNA Diagnosis of Neurofibromatosis 2

1993 • 59 citations

Neurofibromatosis 2 antisense oligodeoxynucleotides induce reversible inhibition of schwannomin synthesis and cell adhesion in STS26T and T98G cells.

1996 • 55 citations

Neurofibromatosis type 2 protein co-localizes with elements of the cytoskeleton.

1995 • 41 citations

Eleven novel mutations in the NF2 tumour suppressor gene

1995 • 25 citations

Laser therapy for benign pigmented cutaneous lesions.

1992 • 17 citations

Predominant Occurrence of Somatic Mutations of the Nf2 Gene in Meningiomas and Schwannomas

1995 • 9 citations

Expression of the neurofibromatosis 2 tumor suppressor gene product, merlin, in Schwann cells

1996 • 5 citations

Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers

1995 • 3 citations