MMP-2 expression during early avian cardiac and neural crest morphogenesis

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Biology and biochemistry of proteinases in tumor invasion

1993 • 1,264 citations

Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

1997 • 1,227 citations

Activation mechanisms of matrix metalloproteinases.

1997 • 1,134 citations

Physiological consequences of loss of plasminogen activator gene function in mice

1994 • 1,051 citations

Mesenchymal derivatives of the neural crest: analysis of chimaeric quail and chick embryos

1975 • 966 citations

Matrix Metalloproteinase-2 Is an Interstitial Collagenase

1995 • 917 citations

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

1998 • 887 citations

The Role of Extracellular Matrix in Development

1985 • 867 citations

Cell-Associated Plasminogen Activation: Regulation and Physiological Functions

1988 • 826 citations

Disruption of Angiogenesis by PEX, a Noncatalytic Metalloproteinase Fragment with Integrin Binding Activity

1998 • 618 citations

Analysis of the early stages of trunk neural crest migration in avian embryos using monoclonal antibody HNK-1

1986 • 454 citations

Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts

1990 • 428 citations

Three-dimensional Type I Collagen Lattices Induce Coordinate Expression of Matrix Metalloproteinases MT1-MMP and MMP-2 in Microvascular Endothelial Cells

1998 • 358 citations

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase

1994 • 299 citations

The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B.

1992 • 297 citations

Cardiac Neural Crest Cells Provide New Insight into Septation of the Cardiac Outflow Tract: Aortic Sac to Ventricular Septal Closure

1998 • 287 citations

Matrix metalloproteinases

1998 • 267 citations

Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure

1999 • 267 citations

A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells

1992 • 259 citations

Experimental study of the development of the truncus and the conus in the chick embryo.

1977 • 248 citations

The Receptor for Urokinase-type Plasminogen Activator Is Not Essential for Mouse Development or Fertility

1995 • 230 citations

8 Growth Factor-Regulated Proteases and Extracellular Matrix Remodeling during Mammalian Development

1990 • 219 citations

Cell surface activation of progelatinase A (proMMP-2) and cell migration

1998 • 201 citations

Myocardialization of the Cardiac Outflow Tract

1999 • 201 citations

Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development.

1995 • 194 citations

Origin and differentiation of cardiac muscle cells in the mouse

1973 • 186 citations

Extracellular Matrix Remodeling during Morphogenesis^a

1998 • 181 citations

Effect of neural crest ablation on development of the heart and arch arteries in the chick

1987 • 176 citations

Connexin 43 Expression Reflects Neural Crest Patterns during Cardiovascular Development

1999 • 172 citations

Neural crest cells in outflow tract septation of the embryonic chicken heart: Differentiation and apoptosis

1998 • 170 citations

Cardiac Morphogenesis—Recent Research Advances

1987 • 164 citations

Early- and late-migrating cranial neural crest cell populations have equivalent developmental potential in vivo

1997 • 156 citations

Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch

1997 • 151 citations

Production of plasminogen activator by migrating cephalic neural crest cells.

1985 • 149 citations

Cardiac neural crest is essential for the persistence rather than the formation of an arch artery

1996 • 148 citations

A role for fibronectin in the migration of avian precardiac cells

1988 • 128 citations

Developmental Mechanisms of Heart Disease

1996 • 126 citations

An anticatalytic monoclonal antibody to avian plasminogen activator: Its effect on behavior of RSV-transformed chick fibroblasts

1986 • 114 citations

Endothelial cell origin and migration in embryonic heart and cranial blood vessel development

1991 • 101 citations

Platelet‐derived growth factor receptor alpha subunit deleted Patch mouse exhibits severe cardiovascular dysmorphogenesis

1995 • 98 citations

A role for fibronectin in the migration of avian precardiac cells

1988 • 93 citations

Temporospatial study of the migration and distribution of cardiac neural crest in quail‐chick chimeras

1991 • 89 citations

Early formation of the vascular system in quail embryos

1993 • 83 citations

Diminished Matrix Metalloproteinase 2 (MMP-2) in Ectomesenchyme-Derived Tissues of the Patch Mutant Mouse: Regulation of MMP-2 by PDGF and Effects on Mesenchymal Cell Migration

1999 • 79 citations

Expression of Matrix Metalloprotease-2-Cleaved Laminin-5 in Breast Remodeling Stimulated by Sex Steroids

1999 • 77 citations

Basal lamina is not a barrier to neural crest cell emigration: documentation by TEM and by immunofluorescent and immunogold labelling

1987 • 73 citations

Distribution of the neural crest cells in the heart of birds: a three dimensional analysis

1989 • 70 citations

Morphogenesis of the truncus arteriosus of the chick embryo heart: The formation and migration of mesenchymal tissue

1979 • 66 citations

Spatial and temporal expression of the 72-kDa type IV collagenase (MMP-2) correlates with development and differentiation of valves in the embryonic avian heart

1997 • 65 citations

Plasminogen activator activity is associated with neural crest cell motility in tissue culture

1989 • 59 citations

Cranial Neural Crest Cells Synthesize and Secrete a Latent Form of Transforming Growth Factor β That Can Be Activated by Neural Crest Cell Proteolysis

1993 • 58 citations

The Isolation, Characterization, and Molecular Cloning of a 75-kDa Gelatinase B-like Enzyme, a Member of the Matrix Metalloproteinase (MMP) Family

2000 • 55 citations

Formation of the primitive myo- and endocardial tubes in the chicken embryo

1989 • 52 citations

Inhibition of urokinase synthesis and cell surface binding alters the motile behavior of embryonic endocardial-derived mesenchymal cells in vitro

1993 • 48 citations

The distribution and spatial organization of the extracellular matrix encountered by mesencephalic neural crest cells

1985 • 47 citations

Urokinase activity in the developing avian heart: A spatial and temporal analysis

1992 • 42 citations

Cloning of a 72 kDa matrix metalloproteinase (gelatinase) from chicken embryo fibroblasts using gene family PCR: expression of the gelatinase increases upon malignant transformation

1994 • 42 citations

Intracellular localization of types i and ii collagen mrna and endoplasmic reticulum in embryonic corneal epithelia

1991 • 26 citations

Urokinase-type plasminogen activator regulates cranial neural crest cell migration in vitro

1996 • 21 citations