The mitogenic effect of H₂O₂ for vascular smooth muscle cells is mediated by an increase of the affinity of basic fibroblast growth factor for its receptor

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

Vitamin E Consumption and the Risk of Coronary Heart Disease in Men

1993 • 2,363 citations

Vitamin E Consumption and the Risk of Coronary Disease in Women

1993 • 2,158 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

1987 • 885 citations

The mammalian ultraviolet response is triggered by activation of src tyrosine kinases

1992 • 874 citations

Replication of smooth muscle cells in vascular disease.

1986 • 770 citations

Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression.

1992 • 653 citations

Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase

1992 • 647 citations

Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.

1990 • 635 citations

Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury.

1989 • 580 citations

Role of basic fibroblast growth factor in vascular lesion formation.

1991 • 521 citations

Cell and tissue responses to oxidative damage.

1993 • 492 citations

PDGF ligand and receptor gene expression during repair of arterial injury.

1990 • 431 citations

Differential Activation of Mitogen-Activated Protein Kinases by H ₂ O ₂ and O ₂ ⁻ in Vascular Smooth Muscle Cells

1995 • 416 citations

Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain.

1989 • 409 citations

The antioxidant butylated hydroxytoluene protects against atherosclerosis.

1991 • 362 citations

Transcriptional activation of early‐response genes by hydrogen peroxide in a mouse osteoblastic cell line

1991 • 298 citations

Generation of Hydroxyl Radical by Enzymes, Chemicals, and Human Phagocytes In Vitro

1979 • 280 citations

The antioxidant hypothesis of cardiovascular disease: epidemiology and mechanisms

1990 • 276 citations

Redox regulation of a protein tyrosine kinase in the endoplasmic reticulum

1991 • 242 citations

Iron release and membrane damage in erythrocytes exposed to oxidizing agents, phenylhydrazine, divicine and isouramil

1992 • 174 citations

Probucol decreases neointimal formation in a swine model of coronary artery balloon injury. A possible role for antioxidants in restenosis.

1993 • 151 citations

Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C

1993 • 137 citations

Activation of hepatocyte protein kinase C by redox-cycling quinones

1989 • 136 citations

Probucol inhibits neointimal thickening and macrophage accumulation after balloon injury in the cholesterol-fed rabbit.

1992 • 130 citations

Modulation of Activator Protein‐1 (AP‐1) Transcription Factor and Protein Kinase C by Hydrogen Peroxide and <scp>d</scp>‐α‐Tocopherol in Vascular Smooth Muscle Cells

1994 • 116 citations

The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor.

1993 • 111 citations

Superoxide as a signal for increase in intracellular pH

1988 • 87 citations

Free radicals and metal ions in health and disease

1987 • 86 citations

Hydrogen peroxide-and fetal bovine serum-induced DNA synthesis in vascular smooth muscle cells: positive and negative regulation by protein kinase C isoforms

1995 • 81 citations

Hypoxia Stimulates Human Endothelial Cells to Release Smooth Muscle Cell Mitogens: Role of Prostaglandins and bFGF

1994 • 79 citations

Oxidation-induced persistent activation of protein kinase C in hippocampal homogenates

1992 • 76 citations

Tissue-type plasminogen activator is a potent mitogen for human aortic smooth muscle cells.

1994 • 71 citations

Disulfide Bonds are Neither Required, Present, Nor Compatible with Full Activity of Human Recombinant Acidic Fibroblast Growth Factor

1990 • 66 citations

Biological equivalence of natural bovine and recombinant human alpha-endothelial cell growth factors.

1987 • 63 citations

Vitamin E: More than an antioxidant

1993 • 53 citations

The induction of ornithine decarboxylase by phorbol 12-myristate 13-acetate or by serum is inhibited by antioxidants

1983 • 49 citations

Effect of Active Oxygen Species on Intimal Proliferation in Rat Aorta after Arterial Injury

1996 • 43 citations

Oxidized LDL and antioxidants

1993 • 42 citations

The Predominant Form of Fibroblast Growth Factor Receptor Expressed by Proliferating Human Arterial Smooth Muscle Cells in Culture Is Type I

1994 • 35 citations

Role of hydroxyl radical in the stimulation of arachidonic acid release caused by H2O2 in pulmonary smooth muscle cells: Protective effect of anion channel blocker

1995 • 7 citations