Redox regulation of a protein tyrosine kinase in the endoplasmic reticulum

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cleavage of structural proteins during the assemble of the head of bacterio-phage T4

1970 • 5,738 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Deglycosylation of asparagine-linked glycans by peptide:N-glycosidase F

1985 • 1,126 citations

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1986 • 1,100 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

Protein Oligomerization in the Endoplasmic Reticulum

1989 • 993 citations

Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1989 • 978 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

1990 • 960 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Purification and Properties of an Endo-β-N-acetylglucosaminidase from Streptomyces griseus

1974 • 870 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

ROLE OF REVERSIBLE OXIDATION-REDUCTION OF ENZYME THIOLS-DISULFIDES IN METABOLIC REGULATION

1985 • 840 citations

The Chronic Myelogenous Leukemia-Specific P210 Protein Is the Product of the bcr / abl Hybrid Gene

1986 • 820 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

High efficiency polyoma DNA transfection of chloroquine treated cells

1983 • 711 citations

endo-beta-N-acetylglucosaminidase F: endoglycosidase from Flavobacterium meningosepticum that cleaves both high-mannose and complex glycoproteins.

1982 • 689 citations

After Insulin Binds

1987 • 687 citations

Protein degradation in the endoplasmic reticulum

1990 • 659 citations

Association between the PDGF receptor and members of the src family of tyrosine kinases

1990 • 650 citations

Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

1990 • 650 citations

Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor

1989 • 531 citations

Peptides and Protein Phosphorylation

2018 • 525 citations

Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum

1989 • 499 citations

Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteins

1988 • 488 citations

Protein disulfide isomerase: Multiple roles in the modification of nascent secretory proteins

1989 • 466 citations

Efficient infection of monkey cells with DNA of simian virus 40.

1981 • 419 citations

Antibodies to the Golgi complex and the rough endoplasmic reticulum.

1982 • 418 citations

Molecular components of the B-cell antigen receptor complex of the IgM class

1990 • 401 citations

Oxidation-Reduction and the Molecular Mechanism of a Regulatory RNA-Protein Interaction

1989 • 387 citations

Identification of multiple novel polypeptide substrates of the v-src, v-yes, v-fps, v-ros, and v-erb-B oncogenic tyrosine protein kinases utilizing antisera against phosphotyrosine.

1988 • 351 citations

The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum

1990 • 310 citations

Evidence that the endogenous heat-stable glucocorticoid receptor-activating factor is thioredoxin.

1983 • 309 citations

Native disulphide bond formation in protein biosynthesis: evidence for the role of protein disulphide isomerase

1984 • 293 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Role of glutathione in the radiation response of mammalian cells invitro and in vivo

1990 • 258 citations

Identification by anti-idiotype antibodies of an intracellular membrane protein that recognizes a mammalian endoplasmic reticulum retention signal

1990 • 248 citations

Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: some applications to radiation and drug resistance in vitro and in vivo.

1986 • 248 citations

Friend spleen focus-forming virus glycoprotein gp55 interacts with the erythropoietin receptor in the endoplasmic reticulum and affects receptor metabolism.

1990 • 244 citations

The cytoskeleton of digitonin-treated rat hepatocytes.

1980 • 238 citations

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain.

1986 • 226 citations

Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores.

1990 • 226 citations

Biosynthesis and glycosylation of the insulin receptor. Evidence for a single polypeptide precursor of the two major subunits.

1983 • 216 citations

Proof that the endogenous, heat-stable glucocorticoid receptor-activating factor is thioredoxin.

1985 • 158 citations

Preparation of Antiserum to Rat Cytochrome P-450 Cholesterol Side Chain Cleavage, and Its Use for Ultrastructural Localization of the Immunoreactive Enzyme by Protein A-Gold Technique*

1986 • 145 citations

Specific phosphorylation of proteins in pore complex-laminae from the sponge Geodia cydonium by the homologous aggregation factor and phorbol ester. Role of protein kinase C in the phosphorylation of DNA topoisomerase II.

1987 • 140 citations

3-Hydroxy-3-methylglutaryl-CoA reductase: a transmembrane glycoprotein of the endoplasmic reticulum with N-linked "high-mannose" oligosaccharides.

1983 • 136 citations

Regulation of membrane IgM expression in secretory B cells: translational and post-translational events.

1987 • 125 citations

Insulin and insulin-like growth factor-I stimulate a common endogenous phosphoprotein substrate (pp185) in intact neuroblastoma cells.

1987 • 120 citations

In vivo cross-linking of protein disulfide isomerase to immunoglobulins

1987 • 113 citations

Deletions into an NH2-terminal hydrophobic domain result in secretion of rotavirus VP7, a resident endoplasmic reticulum membrane glycoprotein.

1985 • 106 citations

Post-translational changes in tertiary and quaternary structure of the insulin proreceptor. Correlation with acquisition of function.

1988 • 105 citations

The cysteine-rich domains of the insulin and insulin-like growth factor I receptors are primary determinants of hormone binding specificity. Evidence from receptor chimeras.

1990 • 104 citations

Formation of disulfides with diamide

1987 • 100 citations

H2O2 potentiates phosphorylation of novel putative substrates for the insulin receptor kinase in intact Fao cells

1989 • 89 citations

The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator.

1990 • 88 citations

Inhibition of protein synthesis initiation by oxidized glutathione: Activation of a protein kinase that phosphorylates the α subunit of eukaryotic initiation factor 2

1978 • 87 citations

Use of gene fusions and protein-protein interaction in the isolation of a biologically active regulatory protein: the replication initiator protein of plasmid R6K.

1983 • 84 citations

Leukocytes express a novel gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain

1988 • 83 citations

Epidermal growth factor stimulates tyrosine phosphorylation of specific proteins in permeabilized human fibroblasts.

1985 • 76 citations

Identification and chromosomal mapping of new human tyrosine kinase genes.

1990 • 75 citations

Post-translational acquisition of insulin binding activity by the insulin proreceptor. Correlation to recognition by autoimmune antibody.

1987 • 73 citations

Neutrophil-derived, oxygen free radical-mediated cardiovascular dysfunction*

1984 • 72 citations

Dna fragmentation and cell death mediated by t cell antigen receptor/cd3 complex on a leukemia t cell line^*

1989 • 70 citations

Oxidation-reduction sensitive interaction of a cellular 50-kDa protein with an RNA hairpin in the 5' noncoding region of the poliovirus genome.

1990 • 60 citations

Thiol/disulfide exchange in the thioredoxin-catalyzed reductive activation of spinach chloroplast fructose-1,6-bisphosphatase. Kinetics and thermodynamics.

1987 • 57 citations

A plasmid vector for cloning and expression of gene segments: expression of an HTLV-I envelope gene segment

1986 • 42 citations

Expression of surface and secreted IgG22a by a murine B-lymphoma before and after hybridization to myeloma cells

1981 • 33 citations

Human ltk: gene structure and preferential expression in human leukemic cells.

1990 • 30 citations

Oncogenes and growth control

1987 • 19 citations

Synthesis and application of DNA and RNA

1988 • 18 citations

Structural Relationships Between Growth Factor Precursors and Cell Surface Receptors

1986 • 8 citations