Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain.

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

1977 • 865 citations

Lipid Peroxides in Biology and Medicine

1982 • 640 citations

A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca ²⁺ -Dependent Protein Kinase

1984 • 618 citations

Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent?

1988 • 408 citations

Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate.

1985 • 387 citations

Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis.

1981 • 347 citations

Competitive inhibition by diacylglycerol of specific phorbol ester binding.

1984 • 306 citations

Evidence for the Involvement of Sulfhydryl Oxidation in the Regulation of Fat Cell Hexose Transport by Insulin

1974 • 209 citations

Protein kinases 1988: a current perspective

1988 • 201 citations

Role of insulin receptor phosphorylation in the insulinomimetic effects of hydrogen peroxide.

1987 • 156 citations

Differential distribution of protein kinase C isozymes in the various regions of brain.

1987 • 150 citations

Activation of soluble guanylate cyclase from rat lung by incubation or by hydrogen peroxide.

1976 • 147 citations

Diminution of mouse epidermal superoxide dismutase and catalase activities by tumor promoters

1981 • 144 citations

Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. Differences between Ca2+-induced and phorbol ester-stabilized membrane bindings of protein kinase C.

1986 • 144 citations

Differential expression of multiple protein kinase C subspecies in rat central nervous tissue

1987 • 135 citations

Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide

1981 • 135 citations

Stimulation of human polymorphonuclear leukocyte superoxide anion radical production by tumor promoters

1981 • 131 citations

Hydrogen peroxide stimulates tyrosine phosphorylation of the insulin receptor and its tyrosine kinase activity in intact cells

1988 • 120 citations

Modulation of Ca2+-activated, phospholipid-dependent protein kinase in platelets treated with a tumor-promoting phorbol ester

1984 • 109 citations

Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.

1988 • 107 citations

Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase

1985 • 70 citations

Susceptibility of protein kinase C to oxidative inactivation: Loss of both phosphotransferase activity and phorbol diester binding

1987 • 63 citations

Stimulation of tyrosine-specific protein phosphorylation in the rat liver plasma membrane by oxygen radicals

1986 • 57 citations

The effects of chemical modification of calmodulin on Ca2+-induced exposure of a hydrophobic region. Separation of active and inactive forms of calmodulin

1985 • 31 citations

Rapid purification of calcium‐activated protease by calcium‐dependent hydrophobic‐interaction chromatography

1985 • 24 citations