Captopril
Data up to Jan 2025
Total Citations Per Year
Abstract
References (566)
Should We STOP Angiotensin Converting Enzyme Inhibitors/Angiotensin Receptor Blockers in Advanced Kidney Disease?
2016 • 11,500 citations
The Effects of Antihypertensive Therapy on the Quality of Life
1986 • 1,344 citations
Effect of Captopril on Progressive Ventricular Dilatation after Anterior Myocardial Infarction
1988 • 1,119 citations
ANGIOTENSIN-CONVERTING ENZYME AND THE COUGH REFLEX
1987 • 744 citations
Captopril-Induced Functional Renal Insufficiency in Patients with Bilateral Renal-Artery Stenoses or Renal-Artery Stenosis in a Solitary Kidney
1983 • 658 citations
Circulating and tissue angiotensin systems.
1987 • 616 citations
A placebo-controlled trial of captopril in refractory chronic congestive heart failure
1983 • 562 citations
Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure.
1986 • 555 citations
TREATMENT OF PATIENTS WITH SYMPTOMLESS LEFT VENTRICULAR DYSFUNCTION AFTER MYOCARDIAL INFARCTION
1988 • 491 citations
Increased plasma arginine vasopressin levels in patients with congestive heart failure
1983 • 481 citations
Circulating versus local renin-angiotensin system in cardiovascular homeostasis.
1988 • 474 citations
Perspectives on systolic hypertension. The Framingham study.
1980 • 467 citations
Effect of Captopril on Heavy Proteinuria in Azotemic Diabetics
1985 • 430 citations
DOUBLE-BLIND COMPARISON OF CAPTOPRIL ALONE AGAINST FRUSEMIDE PLUS AMILORIDE IN MILD HEART FAILURE
1987 • 429 citations
Captopril in heart failure. A double blind controlled trial.
1984 • 385 citations
The M‐Value, an Index of Blood‐sugar Control in Diabetics
1965 • 382 citations
Sustained Effectiveness of Converting-Enzyme Inhibition in Patients with Severe Congestive Heart Failure
1980 • 380 citations
Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure.
1986 • 372 citations
A SPECIFIC ORALLY ACTIVE INHIBITOR OF ANGIOTENSIN-CONVERTING ENZYME IN MAN
1977 • 332 citations
Captopril
1988 • 318 citations
Captopril
1980 • 315 citations
Effect of captopril on kidney function in insulin-dependent diabetic patients with nephropathy.
1986 • 313 citations
Comparison of Captopril and Enalapril in Patients with Severe Chronic Heart Failure
1986 • 293 citations
Enalapril in patients with chronic heart failure: a placebo-controlled, randomized, double-blind study.
1984 • 267 citations
Enalapril
1986 • 258 citations
Acute and long-term response to an oral converting-enzyme inhibitor, captopril, in congestive heart failure.
1980 • 258 citations
Antihypertensive therapy with MK 421: angiotensin II--renin relationships to evaluate efficacy of converting enzyme blockade.
1982 • 243 citations
Enalapril improves systemic and renal hemodynamics and allows regression of left ventricular mass in essential hypertension
1984 • 239 citations
Controlled trial of captopril in chronic heart failure: a rest and exercise hemodynamic study.
1983 • 234 citations
Converting enzyme inhibition with an orally active compound in hypertensive man.
1979 • 224 citations
Contribution of prostaglandins to the antihypertensive action of captopril in essential hypertension.
1981 • 219 citations
Captopril
1982 • 217 citations
Enalapril maleate and a lysine analogue (MK‐521): disposition in man.
1982 • 213 citations
Functional Renal Insufficiency During Long-Term Therapy with Captopril and Enalapril in Severe Chronic Heart Failure
1987 • 212 citations
Regression of left ventricular hypertrophy from systemic hypertension by enalapril
1984 • 211 citations
Cough associated with captopril and enalapril.
1987 • 209 citations
Effect of enalapril on ventricular arrhythmias in congestive heart failure
1985 • 192 citations
LONG-TERM EFFECTS OF CAPTOPRIL (SQ14 225) ON BLOOD-PRESSURE AND HORMONE LEVELS IN ESSENTIAL HYPERTENSION
1979 • 191 citations
ANTIHYPERTENSIVE EFFECT OF THE NEW ORAL ANGIOTENSIN CONVERTING ENZYME INHIBITOR "MK-421".
1981 • 189 citations
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS: PAST, PRESENT, AND BRIGHT FUTURE
1985 • 186 citations
Interruption of the renin-angiotensin system in hypertensive patients by captopril induces sustained reduction in aldosterone secretion, potassium retention and natruiresis.
1979 • 185 citations
Acute regional circulatory and renal hemodynamic effects of converting-enzyme inhibition in patients with congestive heart failure.
1981 • 179 citations
Defect in the sodium-modulated tissue responsiveness to angiotensin II in essential hypertension.
1983 • 178 citations
Disposition of captopril in normal subjects
1980 • 161 citations
Persistent Tissue Converting Enzyme Inhibition Following Chronic Treatment with Hoe498 and MK421 in Spontaneously Hypertensive Rats
1985 • 157 citations
Correction of abnormal renal blood flow response to angiotensin II by converting enzyme inhibition in essential hypertensives.
1985 • 154 citations
The Relationship of Blood Pressure to Diet and Lifestyle in Two Religious Populations
1983 • 153 citations
Is Tissue Converting Enzyme Inhibition a Determinant of the Antihypertensive Efficacy of Converting Enzyme Inhibitors? Studies with the Two Different Compounds, Hoe498 and MK421, in Spontaneously Hypertensive Rats
1984 • 151 citations
Angiotensin-converting enzyme inhibition and prostaglandins
1982 • 149 citations
Actions of angiotensin on adrenergic nerve endings.
1978 • 149 citations
Three new long-acting converting-enzyme inhibitors: Relationship between plasma converting-enzyme activity and response to angiotensin I
1981 • 146 citations
Captopril
1983 • 146 citations
Pharmacokinetics of Captopril in Healthy Subjects and in Patients with Cardiovascular Diseases
1988 • 146 citations
Splint renal function after captopril in unilateral renal artery stenosis.
1984 • 146 citations
Effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro and its ethyl ester (MK-421) on angiotensin converting enzyme in vitro and angiotensin I pressor responses in vivo.
1981 • 146 citations
Discrepancy between antihypertensive effect and angiotensin converting enzyme inhibition by captopril.
1980 • 145 citations
Factors related to first dose hypotensive effect of captopril: prediction and treatment.
1983 • 138 citations
The physiological disposition and metabolism of enalapril maleate in laboratory animals.
1982 • 134 citations
Interaction of angiotensin-converting enzyme inhibitors with the function of the sympathetic nervous system
1982 • 133 citations
Sexual symptoms in hypertensive patients. A clinical trial of antihypertensive medications.
1988 • 133 citations
Acute and long-term effects of enalapril on the cardiovascular response to exercise and exercise tolerance in patients with congestive heart failure
1985 • 133 citations
Renal Response to Captopril in Severe Heart Failure: Role of Furosemide in Natriuresis and Reversal of Hyponatremia
1984 • 132 citations
A cooperative multicenter study of captopril in congestive heart failure: Hemodynamic effects and long-term response
1985 • 131 citations
Changes in cerebral blood flow in patients with severe congestive cardiac failure before and after captopril treatment
1984 • 128 citations
Hemodynamic and clinical response to enalapril, a long-acting converting-enzyme inhibitor, in patients with congestive heart failure.
1984 • 126 citations
Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure. The Captopril-Digoxin Multicenter Research Group
1988 • 126 citations
Lisinopril
1988 • 124 citations
Effects of enalapril, a new angiotensin-converting enzyme inhibitor, in a controlled trial in heart failure
1985 • 122 citations
Effect of vasodilators on survival in chronic congestive heart failure
1985 • 120 citations
Calcium-channel blockade with nifedipine and angiotensin converting-enzyme inhibition with captopril in the therapy of patients with severe primary hypertension.
1984 • 120 citations
Antihypertensive activity of N-[(S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-Ala-L-Pro (MK-421), an orally active converting enzyme inhibitor.
1981 • 119 citations
Pharmacodynamics of converting enzyme inhibition: the cardiovascular, endocrine and autonomic effects of MK421 (enalapril) and MK521.
1982 • 119 citations
Relation between serum sodium concentration and the hemodynamic and clinical responses to converting enzyme inhibition with captopril in severe heart failure
1984 • 116 citations
Captopril kinetics
1982 • 116 citations
Increased cough reflex associated with angiotensin converting enzyme inhibitor cough.
1987 • 116 citations
The effect of captopril (SQ14,225) upon mother and fetus in the chronically cannulated ewe and in the pregnant rabbit.
1982 • 116 citations
Alterations in left ventricular function and coronary hemodynamics with captopril, hydralazine and prazosin in chronic ischemic heart failure: a comparative study.
1982 • 115 citations
Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects
2004 • 114 citations
Lack of relationship between the short-term hemodynamic effects of captopril and subsequent clinical responses.
1984 • 114 citations
Clinical importance of the renin-angiotensin system in chronic heart failure: double blind comparison of captopril and prazosin.
1985 • 114 citations
An overview of the clinical pharmacology of enalapril.
1984 • 113 citations
PLACEBO-CONTROLLED COMPARISON OF CAPTOPRIL, ATENOLOL, LABETALOL, AND PINDOLOL IN HYPERTENSION COMPLICATED BY INTERMITTENT CLAUDICATION
1987 • 113 citations
Systemic and regional hemodynamic effects of captopril and milrinone administered alone and concomitantly in patients with heart failure.
1985 • 112 citations
Therapeutic implications of hypertension-induced glomerular injury: Comparison of enalapril and a combination of hydralazine, reserpine, and hydrochlorothiazide in an experimental model
1985 • 111 citations
Enalapril maleate and a lysine analogue (MK‐521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system.
1982 • 109 citations
Effects of converting enzyme inhibitors: Ramipril and enalapril on peptide action and sympathetic neurotransmission in the isolated heart
1985 • 107 citations
Enalapril: A new angiotensin-converting enzyme inhibitor in chronic heart failure: Acute and chronic hemodynamic evaluations
1983 • 106 citations
Enalapril Worldwide Experience
1984 • 105 citations
Actions of angiotensin on adrenergic nerve endings.
1978 • 104 citations
Captopril: Pharmacology, Metabolism, and Disposition
1984 • 104 citations
Captopril in primary pulmonary hypertension.
1983 • 101 citations
Hemodynamic and volume changes associated with captopril.
1980 • 98 citations
Dependence of enhanced maximal exercise performance on increased peak skeletal muscle perfusion during long-term captopril therapy in heart failure
1987 • 98 citations
Comparison of captopril and hydrochlorothiazide alone and in combination in mild to moderate essential hypertension.
1982 • 96 citations
Effects of intradermal bradykinin after inhibition of angiotensin converting enzyme.
1987 • 93 citations
Racial differences in response to low-dose captopril are abolished by the addition of hydrochlorothiazide.
1982 • 93 citations
Sympathetic responsiveness and plasma norepinephrine during therapy of chronic congestive heart failure with captopril
1982 • 93 citations
The contributions of sympathetic tone and the renin-angiotensin system to severe chronic congestive heart failure: Response to specific inhibitors (prazosin and captopril)
1982 • 92 citations
Captopril in Human Blood and Breast Milk
1981 • 92 citations
Cardiovascular effects and regional blood flow distribution associated with angiotensin converting enzyme inhibition (captopril) in essential hypertension
1985 • 90 citations
Worsening of Anemia Induced by Long-Term Use of Captopril in Hemodialysis Patients
1984 • 89 citations
Pharmacokinetics of repeated single oral doses of enalapril maleate (mk‐421) in normal volunteers
1984 • 88 citations
Converting enzyme inhibitor therapy limits progressive glomerular injury in rats with renal insufficiency
1985 • 87 citations
Effects of enalapril, a new converting enzyme inhibitor, in hypertension
1982 • 83 citations
Increase in plasma aldosterone during prolonged captopril treatment
1982 • 83 citations
Captopril in the Treatment of the Elderly Hypertensive Patient
1985 • 83 citations
Enalapril Maleate (MK-421), a Potent, Nonsulfhydryl Angiotensin-Converting Enzyme Inhibitor: Absorption, Disposition, and Metabolism in Man
1983 • 82 citations
Effects of captopril on survival in patients with heart failure
1988 • 79 citations
Enalapril
1985 • 78 citations
Regulation of renal hemodynamics and glomerular filtration in patients with renovascular hypertension during converting enzyme inhibition with captopril
1984 • 78 citations
Responses to captopril and hydrochlorothiazide in black patients with hypertension
1982 • 78 citations
Systolic and diastolic blood pressures as predictors of coronary heart disease mortality in the Whitehall study.
1985 • 78 citations
Renal handling of captopril: Effect of probenecid
1982 • 77 citations
Efficacy and Safety of Captopril in the Treatment of Severe Childhood Hypertension: Report of the International Collaborative Study Group
1985 • 77 citations
Variable response to oral angiotensin‐converting‐enzyme blockade in hypertensive scleroderma patients
1982 • 75 citations
Structural changes of large arteries in sustained essential hypertension.
1984 • 74 citations
Clinical use of an orally acting converting enzyme inhibitor: captopril.
1980 • 74 citations
Antihypertensive Treatment Using Calcium Antagonists in Combination with Captopril Rather than Diuretics
1985 • 74 citations
Comparison of effects of enalapril plus hydrochlorothiazide versus standard triple therapy on renal function in renovascular hypertension
1985 • 73 citations
Acute hypotensive effect of captopril in man modified by prostaglandin synthesis inhibition.
1982 • 73 citations
Biological Properties of the Angiotensin-Converting Enzyme Inhibitor Cilazapril
1985 • 72 citations
Captopril in Hypertension
1985 • 72 citations
Determination of captopril in blood and urine by high-performance liquid chromatography.
1981 • 71 citations
Non-sulfhydryl-containing angiotensin-converting enzyme inhibitor (MK421): evidence for role of renin system in normotensive subjects.
1981 • 70 citations
Clinical Course of Patients with Scleroderma Renal Crisis Treated with Captopril
1981 • 69 citations
Peripheral large arteries and the response to antihypertensive treatment.
1983 • 68 citations
Enalapril in essential hypertension: a comparative study with propranolol. Enalapril in Hypertension Study Group (UK).
1984 • 68 citations
Long-term efficacy of captopril in renovascular and essential hypertension
1982 • 67 citations
Controlled trial of enalapril in congestive cardiac failure.
1985 • 67 citations
Hemodynamic and radionuclide effects of acute captopril therapy for heart failure: changes in left and right ventricular volumes and function at rest and during exercise.
1982 • 67 citations
Captopril-Associated Cholestatic Jaundice
1985 • 67 citations
Use of Captopril as Early Therapy for Renal Scleroderma: A Prospective Study
1985 • 66 citations
Evaluation of a long-acting converting enzyme inhibitor (Enalapril) for the treatment of chronic congestive heart failure
1983 • 65 citations
Enalapril (MK421) and its lysine analogue (MK521): a comparison of acute and chronic effects on blood pressure, renin‐angiotensin system and sodium excretion in normal man.
1984 • 65 citations
Comparison of oral MK 421 and propranolol in mild to moderate essential hypertension and their effects on arterial and venous vessels of the forearm
1984 • 65 citations
High-Performance Liquid Chromatographic Analysis of Captopril in Plasma
1981 • 65 citations
The effect of enalapril on baroreceptor mediated reflex function in normotensive subjects.
1985 • 64 citations
Effect of Captopril on Renal Vascular Tone in Patients with Essential Hypertension
1979 • 64 citations
Selective activation of the converting enzyme inhibitor MK 421 and comparison of its active diacid form with captopril in different tissues of the rat
1982 • 64 citations
Role of Angiotensin Converting Enzyme Inhibitors in Essential and Renal Hypertension
1984 • 64 citations
Effect of Food on the Bioavailability of Captopril in Healthy Subjects
1982 • 64 citations
Parallel adrenal and renal abnormalities in young patients with essential hypertension
1982 • 63 citations
Transient renal dysfunction during initial inhibition of converting enzyme in congestive heart failure.
1984 • 63 citations
Gas chromatography/selected ion monitoring mass spectrometric determination of captopril in human blood
1980 • 62 citations
Haemodynamic and hormonal effects of captopril in primary pulmonary hypertension.
1982 • 61 citations
Haemodynamic Responses to Specific Renin-Angiotensin Inhibitors in Hypertension and Congestive Heart Failure A Review
1984 • 61 citations
Fatal Pancytopenia Associated with the Use of Captopril
1981 • 60 citations
Disposition of enalapril in the perfused rat intestine-liver preparation: absorption, metabolism and first-pass effect.
1985 • 60 citations
Renal insufficiency with combinations of angiotensin converting enzyme inhibitors and diuretics.
1984 • 60 citations
Captopril in the Treatment of Scleroderma Renal Crisis
1984 • 59 citations
Captopril in essential hypertension; contrasting effects of adding hydrochlorothiazide or propranolol.
1982 • 59 citations
Effect of angiotensin-converting enzyme inhibitor therapy on proteinuria in children with renal disease
1988 • 59 citations
Long-term control of congestive heart failure with captopril
1982 • 59 citations
Influence of Food on the Bioavailability of Enalapril
1984 • 57 citations
Increased renal plasma flow in long-term enalapril treatment of hypertension
1983 • 57 citations
Effects of converting enzyme inhibition on split renal function in renovascular hypertension.
1986 • 57 citations
Treatment of hypertension with captopril: preservation of regional blood flow and reduced platelet aggregation.
1988 • 56 citations
Comparison of angiotensin converting enzyme inhibitors captopril and MK421-diacid in guinea pig atria
1982 • 56 citations
Captopril as treatment for patients with pulmonary hypertension. Problem of variability in assessing chronic drug treatment.
1982 • 55 citations
New evidence for brain angiotensin and for its role in hypertension.
1983 • 55 citations
Determination of captopril in human blood by high-performance liquid chromatography with electrochemical detection
1982 • 55 citations
Converting-enzyme inhibition and coronary blood flow.
1987 • 54 citations
New potent inhibitors of angiotensin converting enzyme
1984 • 54 citations
Blood concentration and urinary excretion of captopril (SQ 14,225) in patients with chronic renal failure.
1981 • 53 citations
In vitro biotransformations of [14C]captopril in the blood of rats, dogs and humans
1981 • 53 citations
Reflex-hemodynamic adjustments and baroreflex sensitivity during converting enzyme inhibition with MK-421 in normal humans.
1983 • 53 citations
Pharmacokinetics of Captopril and Its Effects on Blood Pressure During Acute and Chronic Administration and in Relation to Food Intake
1985 • 52 citations
Overall tolerance and safety of enalapril.
1984 • 52 citations
Haemodynamic, hormonal, and electrolyte effects of enalapril in heart failure.
1983 • 51 citations
Captopril: pharmacokinetics, antihypertensive and biological effects in hypertensive patients.
1984 • 51 citations
The effects of captopril on serum digoxin and urinary urea and digoxin clearances in patients with congestive heart failure
1986 • 51 citations
Effects of captopril in acute and chronic heart failure. Correlations with plasma levels of noradrenaline, renin, and aldosterone.
1983 • 51 citations
Clinical pharmacology of enalapril.
1984 • 51 citations
Haemodynamic and myocardial metabolic effects of captopril in chronic heart failure.
1982 • 50 citations
Post marketing surveillance of captopril (for hypertension): a preliminary report.
1987 • 49 citations
Time Course and Effect of Sodium Intake on Vascular and Hormonal Responses to Enalapril (MK 421) in Normal Subjects
1983 • 49 citations
Disposition of enalapril and its diacid metabolite, enalaprilat, in a perfused rat liver preparation. Presence of a diffusional barrier for enalaprilat into hepatocytes.
1984 • 49 citations
Long-term antihypertensive therapy with captopril.
1983 • 49 citations
Regional and systemic metabolic effects of angiotensin-converting enzyme inhibition during exercise in patients with severe heart failure.
1982 • 48 citations
Enalapril in the treatment of hypertension with renal artery stenosis.
1983 • 48 citations
Captopril: contrasting effects of adding hydrochlorothiazide, propranolol, or nifedipine.
1985 • 48 citations
Cardiac and haemodynamic effects of enalapril.
1983 • 48 citations
Elimination kinetics of captopril in patients with renal failure
1984 • 47 citations
Safety issues during antihypertensive treatment with angiotensin converting enzyme inhibitors
1988 • 47 citations
Renal hemodynamics in essential and renovascular hypertension
1984 • 47 citations
Long-term hemodynamic and clinical efficacy of captopril therapy in ambulatory management of severe chronic congestive heart failure
1982 • 47 citations
Comparison of antihypertensive and hormonal effects of captopril and propranolol at rest and during exercise
1982 • 47 citations
A controlled multiclinic study to compare the antihypertensive effects of MK-421, hydrochlorothiazide, and MK-421 combined with hydrochlorothiazide in patients with mild to moderate essential hypertension.
1984 • 47 citations
Cutaneous reactions to captopril
1984 • 46 citations
Synergistic effect of captopril with hydrochlorothiazide for the treatment of low-renin hypertensive black patients.
1983 • 46 citations
Clinical and hemodynamic experience with enalapril in congestive heart failure
1985 • 46 citations
Captopril and Nifedipine Interactions in the Treatment of Essential Hypertensives: A Crossover Study
1987 • 46 citations
Acute Haemodynamic and Hormonal Effects of Captopril are Diminished by Indomethacin
1982 • 46 citations
Response of the systemic and pulmonary circulation to converting-enzyme inhibition (captopril) at rest and during exercise in hypertensive patients.
1982 • 45 citations
Hemodynamic effects of captopril in pulmonary hypertension of collagen vascular disease
1982 • 45 citations
Attenuation of pressor responses to norepinephrine and pitressin and potentiation of pressor response to angiotensin II by captopril in human subjects.
1982 • 45 citations
Effect of captopril on the cerebral circulation in chronic heart failure
1986 • 45 citations
A Comparative Pilot Study of Enalapril, A New Converting Enzyme Inhibitor, and Hydrochlorothiazide in Essential Hypertension
1982 • 45 citations
Relationship between angiotensin I blockade and antihypertensive properties of single doses of MK-421 and captopril in spontaneous and renal hypertensive rats
1981 • 45 citations
Usefulness of plasma renin activity in predicting haemodynamic and clinical responses and survival during long term converting enzyme inhibition in severe chronic heart failure. Experience in 100 consecutive patients.
1985 • 44 citations
Pharmacokinetics and Pharmacodynamics of Enalapril in Patients with Congestive Heart Failure and Patients with Hypertension
1985 • 44 citations
Captopril and nifedipine in combination for moderate to severe essential hypertension.
1987 • 44 citations
A Double-Blind Comparison of Lisinopril with Captopril in Patients with Symptomatic Congestive Heart Failure
1987 • 43 citations
Long-term haemodynamic effects of enalapril (alone and in combination with hydrochlorothiazide) at rest and during exercise in essential hypertension.
1984 • 43 citations
Hormonal and Metabolic Effects of Angiotensin Converting Enzyme Inhibitors
1984 • 43 citations
Determination of captopril and its mixed disulphides in plasma and urine by high-performance liquid chromatography
1985 • 43 citations
Autonomic and baroreflex function after captopril in hypertension
1983 • 42 citations
A Comparison of Enalapril plus Hydrochlorothiazide with Standard Triple Therapy in Renovascular Hypertension
1986 • 42 citations
Effect of Dietary Sodium on Angiotensin-converting Enzyme (ACE) Inhibition and the Acute Hypotensive Effect of Enalapril (MK-421) in Essential Hypertension
1984 • 42 citations
Effects of Acute and Chronic Angiotensin-Converting Enzyme Inhibition on Large Arteries in Human Hypertension
1985 • 42 citations
Pharmacokinetic properties of captopril after acute and chronic administration to hypertensive subjects
1982 • 41 citations
Determinants of acute and long-term response to converting enzyme inhibitors in congestive heart failure
1982 • 41 citations
Comparison of the hormonal and renal effects of captopril in severe essential and renovascular hypertension
1982 • 41 citations
The effect of captopril on renal, coronary, and systemic hemodynamics in patients with severe congestive heart failure
1982 • 41 citations
Low‐Dose Captopril in Mild to Moderate Geriatric Hypertension
1986 • 40 citations
Comparative Studies: Enalapril Versus Hydrochlorothiazide as First-Step Therapy for the Treatment of Primary Hypertension
1984 • 40 citations
Angiotensin-converting enzyme labeled with [3H]captopril. Tissue localizations and changes in different models of hypertension in the rat.
1987 • 40 citations
Mechanism of deterioration in renal function in patients with renovascular hypertension treated with enalapril.
1984 • 39 citations
Enalapril in Treatment of Hypertension with Renal Artery Stenosis
1984 • 39 citations
Reversal of left ventricular hypertrophy with captopril: Heterogeneity of response among hypertensive patients
1983 • 39 citations
Hemodynamic effects of captopril in patients with severe chronic heart failure
1982 • 39 citations
Influence of Renal Function on the Hemodynamic and Clinical Responses to Long-Term Captopril Therapy in Severe Chronic Heart Failure
1986 • 38 citations
Comparative hemodynamic and clinical effects of long-term treatment with prazosin and captopril for severe chronic congestive heart failure secondary to coronary artery disease or idiopathic dilated cardiomyopathy
1986 • 38 citations
Combined gas chromatographicmass spectrometric procedure for the measurement of captopril and sulfur-conjugated metabolites of captopril in plasma and urine
1984 • 38 citations
Efficacy of captopril in low-renin congestive heart failure: Importance of sustained reactive hyperreninemia in distinguishing responders from nonresponders
1984 • 38 citations
Captopril Overdose Resulting in Hypotension
1988 • 37 citations
Hemodynamic and humoral interactions between captopril and nifedipine.
1983 • 37 citations
Determination of Captopril in Human Blood and Urine by GLC-Selected Ion Monitoring Mass Spectrometry after Oral Coadministration with Its Isotopomer
1982 • 37 citations
Relationship of antihypertensive effect of enalapril to serum MK-422 levels and angiotensin converting enzyme inhibition.
1983 • 37 citations
Redistribution of regional blood flow following angiotensin-converting enzyme inhibition
1984 • 37 citations
Central and peripheral indices of sympathetic activity after blood pressure lowering with enalapril (MK-421) or hydralazine in normotensive rats.
1984 • 37 citations
Captopril in Hypertension with Renal Artery Stenosis and in Intractable Hypertension; Acute and Chronic Changes in Circulating Concentrations of Renin, Angiotensins I and II and Aldosterone, and in Body Composition
1979 • 37 citations
Impairment of captopril bioavailability by concomitant food and antacid intake.
1984 • 37 citations
Antihypertensive and renal effects of captopril in relation to renin activity and bradykinin-induced vasodilation
1982 • 37 citations
Eye pain with nifedipine and disturbance of taste with captopril: a mutually controlled study showing a method of postmarketing surveillance
1988 • 37 citations
Acute and long-term effects of captopril on exercise cardiac performance and exercise capacity in congestive heart failure
1982 • 36 citations
A Comparison of Minoxidil and Hydralazine in Non-azotemic Hypertensives
1983 • 36 citations
Endocrine profile in the long-term phase of converting-enzyme inhibition
1980 • 35 citations
Duration of Action and Short-Term Hormonal Responses to Enalapril (MK 421) in Normal Subjects
1984 • 35 citations
Endocrine and Cardiovascular Influences of Converting Enzyme Inhibition with SQ 14225 in Hypertensive Patients in the Supine Position and during Head-Up Tilt before and after Sodium Depletion*
1980 • 35 citations
Antihypertensive Effect of Enalapril as First-Step Treatment of Mild and Moderate Uncomplicated Essential Hypertension
1984 • 34 citations
Hemodynamic effects of captopril in essential hypertension, renovascular hypertension and cardiac failure: Correlations with short- and long-term effects on plasma renin
1982 • 34 citations
Hypertensive crisis in systemic sclerosis: treatment with the new oral angiotensin converting enzyme inhibitor mk 421 (enalapril) in captopril‐intolerant patients
1984 • 34 citations
Cardiac Regression and Blood Pressure Control in the Dahl Rat Treated with either Enalapril Maleate??(MK 421, an Angiotensin Converting Enzyme Inhibitor) or Hydrochlorothiazide
1983 • 34 citations
Captopril: 4 years of post marketing surveillance of all patients in New Zealand.
1987 • 34 citations
Antihypertensive and metabolic effects of a new converting enzyme inhibitor, enalapril
1983 • 34 citations
Hemodynamic and endocrine changes associated with captopril in diuretic-resistant hypertensive patients
1982 • 34 citations
Long‐term experience with captopril in severe hypertension.
1982 • 34 citations
Angiotensin-converting enzyme inhibition, catecholamines and hemodynamics in essential hypertension
1982 • 34 citations
Effect of naloxone on the actions of captopril
1985 • 34 citations
"Scalded mouth" caused by angiotensin-converting-enzyme inhibitors.
1982 • 34 citations
Age and antihypertensive drugs (hydrochlorothiazide, bendroflumethiazide, nadolol and captopril)
1988 • 34 citations
Angiotensin converting enzyme inhibitors and quality of life: the European trial.
1985 • 34 citations
Hemodynamic responses to combined therapy with captopril and hydralazine in patients with severe heart failure
1983 • 33 citations
Comparative Antihypertensive Effects of Enalapril Maleate and Hydrochlorothiazide, Alone and in Combination
1983 • 33 citations
Psychotropic effects of enalapril maleate in normal volunteers
1985 • 33 citations
Hemodynamic and regional blood flow response to captopril in congestive heart failure
1984 • 33 citations
Regulation of angiotensin converting enzyme.
1983 • 33 citations
Role of sympathetic nervous system activity in the blood pressure response to long-term captopril therapy in severely hypertensive patients
1982 • 32 citations
Enalapril in Hypertension and Congestive Heart Failure
1985 • 32 citations
Comparative effects of captopril and isosorbide dinitrate on pulmonary arteriolar resistance and right ventricular function in patients with severe left ventricular failure: Results of a randomized crossover study
1985 • 32 citations
Effects of captopril on hepatic venous pressure and blood flow in patients with liver cirrhosis
1984 • 32 citations
Hemodynamic and antihypertensive effects of the new oral angiotensin-converting-enzyme inhibitor MK-421 (enalapril).
1984 • 32 citations
Zinc Deficiency during Captopril Treatment
1983 • 32 citations
Immunoreactive bradykinin and [des-Arg9]-bradykinin in low-renin essential hypertension--before and after treatment with enalapril (MK 421).
1983 • 31 citations
Acute Oral Captopril Inhibits Angiotensin Converting Enzyme Activity in Human Cerebrospinal Fluid
1987 • 31 citations
Converting-enzyme inhibition for severe chronic heart failure: views from a skeptic
1985 • 31 citations
Captopril kinetics in chronic congestive heart failure
1982 • 31 citations
2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2- azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498): antihypertensive action and persistent inhibition of tissue converting enzyme activity in spontaneously hypertensive rats.
1984 • 31 citations
Effects of captopril and enalapril on regional vascular resistance and reactivity in spontaneously hypertensive rats.
1983 • 31 citations
Action of Vasodilating Drugs on Small and Large Arteries of Hypertensive Patients
1983 • 30 citations
Antihypertensive Drug Therapy with Captopril in Children and Adolescents
1986 • 30 citations
Spectrofluorometric Determination of Captopril plus Captopril Disulfide Metabolites in Plasma
1984 • 30 citations
Low-Dose Captopril
1982 • 30 citations
Enalapril and Lisinopril in Renovascular Hypertension Antihypertensne and Hormonal Effects of Two New Angio-Tensin-Converting-Enzyme (ACE) Inhibitors
1984 • 29 citations
Quantitative Determination of Captopril in Blood and Captopril and Its Disulfide Metabolites in Plasma by Gas Chromatography
1984 • 29 citations
Simplified determination of captopril in plasma by high-performance liquid chromatography
1988 • 29 citations
Influence of chronic renal failure on captopril pharmacokinetics and clinical and biological effects in hypertensive patients.
1984 • 29 citations
Pharmacokinetics of Captopril in Elderly Healthy Male Volunteers
1986 • 29 citations
Haemodynamic and neurohumoral response to exercise in patients with congestive heart failure treated with captopril.
1985 • 29 citations
Resolution of Captopril‐Induced Rash After Substitution of Enalapril
1983 • 29 citations
Reduction of plasma and urinary vasopressin during treatment of severe hypertension by captopril
1981 • 29 citations
MK 421 and prevention of genetic hypertension development in young spontaneously hypertensive rats
1982 • 29 citations
Treating Hypertension in Non‐insulin‐Dependent Diabetes: A Comparison of Atenolol, Nifedipine, and Captopril Combined with Bendrofluazide
1987 • 29 citations
Induction of angiotensin-converting enzyme with the ACE inhibitory compound MK-421 in rat lung
1982 • 29 citations
Enalapril, a nonsulfhydryl angiotensin-converting enzyme inhibitor.
1985 • 28 citations
Acute and chronic effect of captropril in hypertensive patients.
1980 • 28 citations
Natriuretic Effect and Changes in Renal Haemodynamics Induced by Enalapril in Essential Hypertension
1985 • 28 citations
Enalapril (MK421) activation in man: importance of liver status.
1985 • 28 citations
Long‐term efficacy of angiotensin‐converting‐enzyme inhibition with captopril in mild‐to‐moderate essential hypertension.
1982 • 27 citations
Long-term antihypertensive, metabolic and cellular effects of enalapril.
1984 • 27 citations
Determination of Total Captopril in Human Plasma by Gas Chromatography-Mass Spectrometry with Selected-Ion Monitoring After Reduction of Disulfides
1984 • 27 citations
Captopril and MK-421: stability on storage, distribution to the central nervous system, and onset of activity.
1983 • 27 citations
Influence of captopril and enalapril on regional vascular alpha-adrenergic receptor reactivity in SHR.
1984 • 27 citations
Reactive Hyper-Reninaemia to Angiotensin Blockade Identifies Renovascular Hypertension
1979 • 27 citations
Effects of Captopril, Hydrochlorothiazide, and Their Combination on Timed Urinary Excretions of Water and Solutes
1985 • 27 citations
Vasodilatation with captopril and prazosin in chronic heart failure: double blind study at rest and on exercise.
1986 • 27 citations
The effect of captopril on blood pressure and glucose tolerance in hypertensive non-insulin dependent diabetics.
1986 • 27 citations
Captopril in hypertension
1982 • 26 citations
Plasma enalapril levels and hormonal effects after short‐ and long‐term administration in essential hypertension.
1984 • 26 citations
The angiotensin converting enzyme inhibitor enalapril and its effects on renal function.
1983 • 26 citations
Inhibition of angiotensin converting enzyme by 2-[N-[(S)-1-carboxy-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2-azabicyclo [3.3.0]octane-3-carboxylic acid (Hoe 498 diacid). Comparison with captopril and enalaprilat.
1984 • 26 citations
Na-K-ATPase in single nephron segments of hypertension-prone rats.
1983 • 26 citations
Pharmacology of Converting Enzyme Inhibitors: New Aspects
1983 • 26 citations
Indomethacin (IND) inhibits an enhanced renin release following the captopril, SQ 14225, administration
1980 • 26 citations
Treatment of neonatal hypertension with Captopril
1982 • 25 citations
Once-daily treatment of essential hypertension with captopril.
1986 • 25 citations
Effects of angiotensin I-converting enzyme inhibitor, SQ 14225, in nomal men.
1979 • 25 citations
Effect of converting enzyme inhibitors in hypertensive patients with non-insulin-dependent diabetes mellitus.
1986 • 25 citations
Enalapril in low-renin essential hypertension
1983 • 25 citations
The role of renal hemodynamics in the antihypertensive effect of captopril
1986 • 25 citations
Effect of Angiotensin Converting Enzyme Inhibitor (Captopril) on Cerebral Blood Flow in Hypertensive Patients without a History of Stroke
1987 • 25 citations
Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by enalapril (MK-421): A new angiotensin-converting enzyme inhibitor
1983 • 24 citations
A Single-Blind, Randomized, Cross-over Study of Angiotensin-Converting Enzyme Inhibitor and Triamterene and Hydrochlorothiazide in the Treatment of Mild to Moderate Hypertension in the Elderly
1987 • 24 citations
In vitro studies on the metabolic pathway of SQ 14225 (captopril) and mechanism of mixed disulfide formation.
1981 • 24 citations
Dilation of forearm blood vessels after angiotensin-converting-enzyme inhibition by captopril in hypertensive patients.
1984 • 24 citations
Quantitative differences in the hemodynamic effects of captopril and nitroprusside in severe chronic heart failure
1983 • 24 citations
Enalapril in Essential Hypertension
1985 • 24 citations
Contrasting hemodynamic responses in severe heart failure: Comparison of captopril and other vasodilator drugs
1982 • 24 citations
Angiotensin-Converting Enzyme Inhibitory Activity of SCH 31846, a New Non-Sulfhydryl Inhibitor
1983 • 24 citations
Self poisoning with enalapril.
1984 • 23 citations
Captopril and domiciliary oxygen in chronic airflow obstruction.
1985 • 23 citations
Effect of acute oral administration of captopril and MK-421 on vascular angiotensis converting enzyme activity in the spontaneously hypertensive rat
1983 • 23 citations
The Therapeutic use of a new Potassium-Sparing Diuretic, Amiloride, and a Converting Enzyme Inhibitor, Mk-421, in Preventing Hypokalemia Associated with Primary and Secondary Hyperaldosteronism
1983 • 23 citations
Long-term effects of captopril on renal function in hypertensive patients
1984 • 23 citations
Influence of Food on Acute and Chronic Effects of Captopril in Essential Hypertensive Patients
1985 • 23 citations
Double-blind comparison between propranolol and bendroflumethiazide in captopril-treated resistant hypertensive patients
1983 • 23 citations
Mechanism for Hypotensive Action of Angiotensin Converting Enzyme Inhibitors
1984 • 23 citations
Captopril in the treatment of hypertension in type I and type II diabetic patients.
1986 • 23 citations
Captopril (SQ 14225) clearance during hemodialysis treatment.
1981 • 23 citations
Acute effects of captopril on cardiopulmonary hemodynamics and renin-angiotensin-aldosterone and bradykinin profile in hypertension
1983 • 23 citations
The disposition and metabolism of captopril
1986 • 23 citations
Kinetic and metabolic aspects of enalapril action.
1984 • 22 citations
Enalapril and autonomic reflexes and exercise performance.
1983 • 22 citations
Regional circulatory response to converting‐enzyme inhibition in congestive heart failure.
1982 • 22 citations
A Radioimmunoassay for Total Captopril in Human Serum or Plasma Samples
1984 • 22 citations
A parallel study of enalapril and captopril and 1 year of experience with enalapril treatment in moderate-to-severe essential hypertension
1985 • 22 citations
Captopril and Hydrochlorothiazide in the Fixed Combination Multicenter Trial
1985 • 22 citations
Hemodynamic and renal function in essential hypertension during treatment with enalapril
1985 • 22 citations
Initial dose of enalapril in hypertension.
1985 • 22 citations
Captopril in essential hypertension.
1982 • 22 citations
Left Ventricular Mass and Function Before and After Antihypertensive Treatment
1983 • 22 citations
The pharmacokinetics of captopril and captopril disulfide conjugates in uraemic patients on maintenance dialysis: Comparison with patients with normal renal function
1987 • 22 citations
Zinc Metabolism during Captopril Treatment
1985 • 22 citations
Regression of Cardiac Hypertrophy after Antihypertensive Therapy with Nifedipine and Captopril
1987 • 22 citations
Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients
1983 • 21 citations
Captopril pharmacokinetics and the acute hemodynamic and hormonal response in patients with severe chronic congestive heart failure
1982 • 21 citations
Effects of captopril on arterial and venous pressure, renal function, and humoral factors in severe chronic congestive heart failure
1984 • 21 citations
Combined Captopril and Hydrochlorothiazide Therapy in Severe Hypertension: Long-term Haemodynamic Changes at Rest and During Exercise
1984 • 21 citations
Chronic Effects of Enalapril on Blood Pressure, Stroke, Plasma Renin, Urinary Electrolytes and PGE2 Excretion in Stroke-Prone Spontaneously Hypertensive Rats
1985 • 21 citations
Converting enzyme inhibition with captopril in patients with primary hyperaldosteronism
1982 • 21 citations
Comparative effect of captopril and nifedipine in normotensive patients with incipient diabetic nephropathy.
1988 • 21 citations
Effects of Converting Enzyme Inhibition on Blood Pressure, Plasma Renin Activity (PRA) and Plasma Aldosterone in Hypertensive Diabetics Compared to Patients With Essential Hypertension
1985 • 21 citations
Intravenous captopril treatment in patients with severe cardiac failure.
1986 • 21 citations
Determination of captopril and its disulphide in biological fluids
1982 • 20 citations
EFFECTS OF CAPTOPRIL ON ABNORMALITIES OF THE PERIPHERAL CIRCULATION AND RESPIRATORY FUNCTION IN PATIENTS WITH SEVERE HEART FAILURE
1984 • 20 citations
Enalapril (MK-421), A New Angiotensin-Converting Enzyme Inhibitor
1983 • 20 citations
Safety and efficacy of enalapril. Summing up the evidence.
1983 • 20 citations
Comparative study of once‐daily administration of captopril 50 mg, hydrochlorothiazide 25 mg and their combination in mild to moderate hypertension.
1987 • 20 citations
Captopril-Associated Transient Aplastic Anemia
1985 • 20 citations
Cerebral blood flow in hypertensive patients with cerebrovascular disease
1985 • 20 citations
Comparative double-blind study of ramipril and captopril in mild to moderate essential hypertension
1987 • 20 citations
Captopril for the Treatment of Patients with Hypertension and Peripheral Vascular Disease
1985 • 20 citations
A Long‐term Follow‐up of Patients with Essential Hypertension Treated with Captopril
1984 • 19 citations
Effects of converting enzyme inhibitor on hepatic blood flow in man
1984 • 19 citations
The Renin-Angiotensin System in the Control of Systemic Arterial Pressure
1985 • 19 citations
Tolerance and safety of enalapril.
1984 • 19 citations
Plasma free captopril concentrations during short and long term treatment with oral captopril for heart failure.
1985 • 19 citations
The clinical pharmacology of antihypertensive drugs.
1984 • 19 citations
Enalapril versus Triple-Drug Therapy in the Treatment of Renovascular Hypertension
1985 • 19 citations
The Role of Angiotensin II in the Development of Hypertension and in the Maintenance of Glomerular Filtration Rate During 48 Hours of Renal Artery Stenosis in Conscious Dogs
1983 • 19 citations
Converting enzyme inhibition and heart failure
1988 • 19 citations
Membranous Glomerulopathy in a Patient on Captopril
1980 • 19 citations
Effective dose range of enalapril in mild to moderate essential hypertension.
1985 • 19 citations
Correlation between angiotensin converting enzyme inhibition and the acute hypotensive response to MK 421 in essential hypertension.
1982 • 19 citations
Captopril attenuates pressor responses to norepinephrine and vasopressin through depletion of endogenous angiotensin II
1982 • 19 citations
Antihypertensive Activity of SCH 31846, a Non-Sulfhydryl Angiotensin-Converting Enzyme Inhibitor
1983 • 19 citations
Total serum angiotensin converting enzyme activity in rats and dogs after enalapril maleate (MK-421)
1982 • 19 citations
Vasodilator therapy of severe congestive heart failure: The special importance of angiotensin-converting enzyme inhibition with captopril
1982 • 19 citations
Blood pressure, plasma volume, and catecholamine levels during enalapril therapy in blacks with hypertension
1984 • 18 citations
Effects of Enalapril on Clinical Status, Biochemistry, Exercise Performance and Haemodynamics in Heart Failure
1985 • 18 citations
Long Term Therapy by Captopril in Children with Renal Hypertension
1986 • 18 citations
Differing Dosages of Captopril and Hydrochlorothiazide in the Treatment of Hypertension
1985 • 18 citations
Captopril and atenolol combined with hydrochlorothiazide in essential hypertension.
1982 • 18 citations
Attenuation of pressor responses to intracerebroventricular angiotensin I by angiotensin converting enzyme inhibitors and their effects on systemic blood pressure in conscious rats
1983 • 18 citations
Captopril
1983 • 18 citations
The brain angiotensin system: subcellular localization and interferences with converting enzyme inhibitors.
1983 • 18 citations
Effect of enalapril (MK-421), an orally active angiotensin I converting enzyme inhibitor, on blood pressure, active and inactive plasma renin, urinary prostaglandin E2, and kallikrein excretion in conscious rats
1984 • 18 citations
Influence of ACE inhibition on pulmonary haemodynamics and function in patients in whom beta-blockers are contraindicated.
1986 • 18 citations
Effects of repeated doses of enalapril on renal function in man.
1985 • 18 citations
Drug points: Gynaecomastia associated with captopril
1988 • 18 citations
Effect of enalapril at rest, during tilt, static and dynamic exercise in systemic hypertension
1985 • 18 citations
Long‐term experience of captopril in the treatment of primary (essential) hypertension.
1982 • 17 citations
Enalapril for severe congestive heart failure
1984 • 17 citations
Cardiac and hormonal effects of enalapril in hypertension
1983 • 17 citations
Fatal bone-marrow suppression associated with captopril.
1981 • 17 citations
Low-dose captopril titration in patients with moderate-to-severe hypertension treated with diuretics.
1983 • 17 citations
Efficacy of an Oral Angiotensin-Converting Enzyme Inhibitor (Captopril) in Severe Hypertension
1981 • 17 citations
The influence of captopril, the nitrates and propranolol on apparent liver blood flow.
1985 • 17 citations
The reversal of left ventricular hypertrophy with control of blood pressure in experimental hypertension
1984 • 17 citations
Captopril in the treatment of hypertension in type I and type II diabetic patients.
1985 • 17 citations
Acute and chronic hemodynamic effects of enalapril (MK-421) in congestive heart failure
1984 • 16 citations
Role of angiotensin-converting enzyme inhibitors in early antihypertensive treatment in non-insulin dependent diabetes mellitus.
1988 • 16 citations
Angiotensin II-Mediated Vasoconstriction in Chronic Congestive Heart Failure, and Response to Converting Enzyme Inhibition
1984 • 16 citations
Glucose Tolerance During Chronic Captopril Therapy in Patients with Essential Hypertension
1987 • 16 citations
Kinetics of inhibition of angiotensin converting enzyme by captopril and by enalapril diacid
1984 • 16 citations
Guillain-Barré neuropathy during treatment with captopril
1987 • 16 citations
The Effect of Captopril on Renal Hemodynamics in Hypertensive Patients
1984 • 15 citations
ATTENUATION OF THE ANTIHYPERTENSIVE EFFECT OF CAPTOPRIL BY THE OPIOID RECEPTOR ANTAGONIST NALOXONE
1983 • 15 citations
Double-blind comparison of captopril and enalapril in mild to moderate hypertension
1986 • 15 citations
Sustained Antihypertensive Effect of Captopril Combined with Diuretics and Beta‐adrenergic Blocking Drugs in Patients with Resistant Hypertension
1983 • 15 citations
Captopril-induced Agranulocytosis in Systemic Sclerosis
1981 • 15 citations
Ramipril and captopril in patients with heart failure: Effects on hemodynamics and vasoconstrictor systems
1987 • 15 citations
Effects of captopril on prostaglandin and natriuresis in patients with essential hypertension
1982 • 15 citations
Efficacy of captopril in hypertensive diabetic patients
1988 • 15 citations
Angiotensin converting enzyme inhibition
1985 • 15 citations
Once-Daily Administration of Captopril and Hypotensive Effect
1985 • 15 citations
A Comparative Study of Captopril and Enalapril in Patients With Severe Hypertension
1985 • 14 citations
Deterioration of renal function in hypertensive patients with scleroderma despite blood pressure normalization with captopril
1984 • 14 citations
Captopril treatment: inter‐dose variations in renin, angiotensins I and II, aldosterone and blood pressure.
1982 • 14 citations
Comparison of Antihypertensive Effects of Captopril and Propranolol in Essential Hypertension
1981 • 14 citations
Evidence for a vasodepressor effect of the angiotensin-converting enzyme inhibitor, MK421 (enalapril), independent of blockade of angiotensin II formation.
1984 • 13 citations
Comparison in normal volunteers of three converting enzyme inhibitors: RHC 3659, MK 421 and captopril
1982 • 13 citations
Effects of captopril and enalapril on sodium excretion and blood pressure in sodium-deficient dogs.
1984 • 13 citations
Long-term captopril therapy in congestive heart failure: Serial hemodynamic and echocardiographic changes
1982 • 13 citations
Analysis of well-being and 24-hour blood pressure recording in a comparative study between indapamide and captopril
1988 • 13 citations
Effects of captopril on renal function in hypertensive patients
1982 • 13 citations
Antihypertensive efficacy and tolerability of captopril in the elderly: comparison with hydrochlorothiazide and placebo in a multicentre, double-blind study.
1987 • 13 citations
Antihypertensive effects of CI-907 (indolapril): a novel nonsulfhydryl angiotensin converting enzyme inhibitor.
1984 • 13 citations
Captopril versus enalapril maleate: a comparison of antihypertensive and hormonal effects.
1985 • 13 citations
Radioimmunoassay of blood bradykinin: purification of blood extracts to prevent cross-reaction with endogenous kininogen
1983 • 12 citations
The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension
1983 • 12 citations
Reproduzierbarkeit einer Captopril-induzierten akuten Niereninsuffizienz durch Enalapril
1984 • 12 citations
Endogenous Prostaglandin E<sub>2</sub> Metabolite Levels, Renin-Angiotensin System and Catecholamines versus Acute Hemodynamic Response to Captopril in Chronic Congestive Heart Failure
1983 • 12 citations
Effect of captopril and hydrochlorothiazide on the response to pressor agents in hypertensives
1985 • 12 citations
Effects of Converting-Enzyme Inhibition on Cardiorenal Hemodynamics in Patients with Chronic Congestive Heart Failure
1985 • 12 citations
Captopril in the treatment of hypertension associated with claudication.
1986 • 12 citations
The effect of captopril on postural hemodynamics and autonomic responses in chronic heart failure
1982 • 12 citations
Identification and Determination of the S-Methyl Metabolite of Captopril in Human Plasma by Selected-Ion Monitoring Gas Chromatography-Mass Spectrometry
1984 • 12 citations
Central Effects of Converting Enzyme Inhibitors
1983 • 11 citations
Serum concentration and effects of a single dose of enalapril maleate in patients with essential hypertension.
1985 • 11 citations
Captopril Withdrawal after Chronic Therapy
1981 • 11 citations
Proteinuria and abnormalities of the renal glomerulus in patients with hypertension.
1982 • 11 citations
The use of captopril and captopril plus frusemide as antihypertensive agents in non-insulin dependent diabetes.
1987 • 11 citations
Differential Effects of Diuresis and Beta‐Adrenoreceptor Blockade During Angiotensin‐Converting Enzyme Inhibition in Patients with Severe Hypertension
1982 • 11 citations
Does captopril cause renal damage in hypertensive patients? Report from the Captopril Collaborative Study Group.
1982 • 11 citations
Acute and long‐term response to enalapril in congestive failure.
1984 • 11 citations
Long‐term Effects of Captopril and Atenolol in Essential Hypertension
1985 • 11 citations
Effects of Captopril, an Angiotensin-Converting Enzyme Inhibitor, in Normotensive Sodium-Replete Volunteers
1982 • 11 citations
Simultaneous determination of captopril and S-benzoyl captopril in human blood by capillary gas chromatography-mass selective detection
1985 • 11 citations
Enalapril in the treatment of hypertension associated with impaired renal function.
1985 • 11 citations
Captopril-induced oesophagitis
1988 • 10 citations
Enalapril versus captopril: a double-blind multicentre comparison in essential hypertension.
1988 • 10 citations
Renal failure due to enalapril and captopril in bilateral renal artery stenosis: greater awareness needed
1988 • 10 citations
Comparative Effects of Enalapril, Enalaprilic Acid and Captopril in Blocking Angiotensin I-Induced Pressor and Dipsogenic Responses in Spontaneously Hypertensive Rats
1984 • 10 citations
A COMPARISON OF THE ACTIVITY OF THE ANGIOTENSIN CONVERTING ENZYME INHIBITORS SQ 14 225, SA 446, AND MK 421
1983 • 10 citations
Long-Term Treatment with Captopril in Pediatric Patients with Severe Hypertension and Chronic Renal Failure
1986 • 9 citations
Malignant Hypertension in Brattleboro (Vasopressin-deficient) Rats
1983 • 9 citations
Low-dose captopril therapy in mild and moderate hypertension. Randomized comparison of twice daily vs three times daily doses.
1983 • 9 citations
Reversible severe thrombocytopaenia associated with captopril therapy.
1986 • 9 citations
POTENTIATION OF DEPRESSOR RESPONSES TO ARACHIDONIC ACID BY ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN THE RAT
1984 • 9 citations
The influence of food intake on pharmacodynamics and plasma concentration of captopril.
1985 • 9 citations
Persistent captopril-associated taste alteration.
1984 • 9 citations
Further Studies on the Hypernoradrenergic State of Treated Hypertensives: Effect of Captopril
1983 • 9 citations
Combined Nifedipine and Captopril Treatment in Moderately Severe Primary Hypertension
1986 • 9 citations
Beneficial effects of captopril in left ventricular failure in patients with myocardial infarction.
1982 • 9 citations
Hemodynamic and Humoral Responses to Enalapril and Nifedipine in the Rat
1984 • 9 citations
Effect of the angiotensin I converting enzyme inhibitor, MK-421, on experimentally induced drinking
1982 • 9 citations
Effects of captopril on pulmonary haemodynamics
1984 • 9 citations
Side Effects and Metabolic Effects of Converting Enzyme Inhibitors
1987 • 9 citations
Converting Enzyme Inhibition in Mild and Moderate Essential Hypertension. II
1986 • 8 citations
Treatment of Renal Hypertension in Children by Captopril
1986 • 8 citations
Effect of enalapril on renin, angiotensin converting enzyme activity, aldosterone and prostaglandins in patients with hypertension.
1985 • 8 citations
[Clinical and hemodynamic effects of nisoldipine and captopril in heart failure: a double-blind comparative study of long and short-term effects].
1987 • 8 citations
Clinical Effects of Low-Dose Captopril Plus a Thiazide Diuretic on Mild to Moderate Essential Hypertension
1985 • 8 citations
Renal Prostaglandin E in the Hypotensive Mechanism of MK-421 in Conscious Rats
1984 • 8 citations
Control of essential hypertension with captopril, an angiotensin converting enzyme inhibitor.
1981 • 8 citations
Reversible captopril-associated bone marrow aplasia.
1985 • 8 citations
Mechanism of Captopril-Induced Agranulocytosis
1981 • 8 citations
Acute antihypertensive synergism of angiotensin-converting enzyme inhibitors and diuretics.
1984 • 8 citations
Physiological effects of short-term treatment with enalapril in hypertensive patients.
1983 • 8 citations
Effect of captopril on plasma prostacyclin concentration in essential hypertensive patients
1985 • 8 citations
Acute effects of MK421, a new angiotensin coverting enzyme inhibitor, in man.
1983 • 8 citations
A STUDY OF THE USE OF CAPTOPRIL IN ELDERLY HYPERTENSIVE PATIENTS
1988 • 8 citations
Serum zinc is unaffected by effective captopril treatment of hypertension.
1987 • 8 citations
Comparison of the effects of captopril, diuretic and their combination in low- and normal-renin essential hypertension
1982 • 8 citations
Minoxidil and captopril in severe hypertension
1986 • 7 citations
Kalemia during combined therapy with an angiotensin converting enzyme inhibitor and a potassium-sparing diuretic.
1987 • 7 citations
Effects of a new angiotensin-converting enzyme inhibitor, MK 421, in normal men and patients.
1982 • 7 citations
Protracted effect of converting-enzyme inhibition on the rat's response to intraarterial bradykinin.
1983 • 7 citations
RELATION OF PLASMA RENIN ACTIVITY TO THE ANTIHYPERTENSIVE EFFECT OF MK 421 IN THE RAT
1982 • 7 citations
Additive Effects of Moderate Dietary Salt Reduction and Captopril in Hypertension
1988 • 7 citations
Sustained haemodynamic and clinical effects of captopril in long‐term treatment of severe chronic congestive heart failure.
1982 • 7 citations
Hemodynamic effects of captopril in chronic heart failure: Efficacy of low-dose treatment and comparison with prazosin
1982 • 7 citations
Role of Endogenous Angiotensin II and Prostaglandins in the Antihypertensive Mechanism of Angiotensin Converting Enzyme Inhibitor in Hypertension
1987 • 7 citations
Selectivity of Converting-Enzyme Inhibitors for Angiotensin I versus Bradykinin Hydrolysis Reactions
1990 • 6 citations
Effect of antihypertensive therapy on left ventricular function and myocardial perfusion at rest and during exercise.
1984 • 6 citations
Prazosin and Captopril in Chronic Heart Failure: Comparison of Acute Haemodynamic and Hormonal Effects
1982 • 6 citations
Effects of Captopril on Peripheral Hemodynamics in Severe Congestive Heart Failure
1987 • 6 citations
A discrepancy between the effects of a single oral dose of captopril on blood pressure, plasma renin activity, and serum angiotensin-converting enzyme levels.
1983 • 6 citations
Antihypertensive effect of MK-421 in rats. Role of the renal kallikrein-kinin system.
1984 • 6 citations
The efficacy and safety of enalapril in moderate to severe essential hypertension.
1984 • 6 citations
Hemolytic anemia: possible complication of captopril therapy.
1983 • 6 citations
Captopril in hypertension after renal transplantation.
1983 • 6 citations
Captopril for Refractory Hypertension in Patients with Impaired Renal Function
1985 • 6 citations
Captopril in hypertension after renal transplantation
1984 • 6 citations
Combined vasodilator therapy for chronic congestive heart failure
1983 • 5 citations
Captopril combined with minoxidil, beta-blocker and furosemide in the treatment of refractory hypertension
1983 • 5 citations
Renal Kallikrein-Kinin System and the Depressor Effect of Angiotensin Converting Enzyme Inhibitors MK 421, SA 446, And Captopril In Rats
1984 • 5 citations
Comparison of Nifedipine and captopril as Third‐Line Agents in Hypertensive Patients Uncontrolled With Beta‐Blocker and Diuretic Therapy
1987 • 5 citations
Captopril-associated granulocytopenia in hypertension after renal transplantation.
1984 • 5 citations
The effect of enalapril on serum prolactin.
1983 • 5 citations
Comparative Immediate Hemodynamic and Hormonal Effects of Amrinone and Captopril in Patients with Severe Chronic Heart Failure
1986 • 5 citations
A double-blind randomized evaluation of converting enzyme inhibition as the first-step treatment of mild to moderate hypertension.
1984 • 5 citations
Captopril and oxprenolol in a fixed combination with thiazide diuretics: comparison of their antihypertensive efficacy and metabolic effects.
1984 • 5 citations
Sustained haemodynamic effects of enalapril in left ventricular failure.
1983 • 5 citations
An appraisal of antihypertensive efficacy and adverse reactions with two drug regimens: enalapril maleate as part of triple therapy compared to conventional triple therapy in moderate to severe hypertension.
1984 • 5 citations
Comparative analysis of the hemodynamic actions of captopril and sodium nitroprusside in severe chronic congestive heart failure
1982 • 5 citations
Combined Treatment With Minoxidil and Captopril in Refractory Hypertension
1983 • 5 citations
Effects of Captopril on Cardiorenal Hemodynamics in Patients with Severe Chronic Congestive Heart Failure
1987 • 4 citations
Captopril and proteinuria in diabetes mellitus.
1987 • 4 citations
Successful management of severe congestive cardiac failure with enalapril
1983 • 4 citations
Effect of captopril at two different dosage regimens in hypertensive non-insulin dependent patients.
1988 • 4 citations
Time course of antihypertensive effect of low-dose captopril in mild to moderate hypertension
1984 • 4 citations
Factors predicting acute and long‐term response to captopril therapy in congestive heart failure.
1982 • 4 citations
Relationship between vasopressin and the renin-angiotensin-aldosterone system in essential hypertension: effect of converting enzyme inhibitor on plasma vasopressin.
1985 • 4 citations
Reversible Panmyelopathie nach Captopril-Medikation
2008 • 4 citations
Kalemia during combined therapy with an angiotensin converting enzyme inhibitor and a potassium-sparing diuretic.
1987 • 4 citations
CAPTOPRIL IN MILD AND SEVERE HYPERTENSION
1980 • 4 citations
Angiotensin converting enzyme inhibitor treatment of hypertension in infancy and childhood.
1984 • 4 citations
A comparison of inhibition of angiotensin I conversion by three converting enzyme inhibitors in rats.
1982 • 4 citations
Survival in patients with heart failure: focus on captopril.
1988 • 3 citations
Acute and Subacute Haemodynamic Effects of Enalapril
1984 • 3 citations
Long‐term captopril treatment in moderate to severe hypertension.
1982 • 3 citations
Haemodynamic effects of enalapril, a new converting enzyme inhibitor, in hypertensive patients
1985 • 3 citations
Leakage of angiotensin converting enzyme inhibitors from the cerebral ventricles into the peripheral circulation in conscious, spontaneously hypertensive rats.
1983 • 3 citations
Effect of captopril on renal haemodynamics and the renin-angiotensin-aldosterone and osmoregulatory systems in essential hypertension
1986 • 3 citations
Naloxone does not modify the antihypertensive effect of captopril in essential hypertensive patients.
1985 • 3 citations
Enalapril Treatment in a Patient With Impaired Renal Function and Intolerance to Captopril
1984 • 3 citations
Different effects of two angiotensin converting enzyme inhibitors in primary hypertension--a comparison of captopril and enalapril.
1986 • 3 citations
Comparison of captopril (SQ 14225) with hydrochlorothiazide in the treatment of essential hypertension.
1981 • 3 citations
Hemodynamic results of perorally administered converting enzyme inhibitors in congestive heart failure.
1984 • 3 citations
Efficacy of Low-Dose Captopril Given Twice Daily to Patients with Essential Hypertension Uncontrolled by a Beta Blocker plus Thiazide Diuretic
1984 • 3 citations
Acute effects of oral captopril on hemodynamics in patients with cor pulmonale.
1986 • 3 citations
Captopril in the treatment of mild essential hypertension.
1982 • 3 citations
[Usefulness of angiotensin converting enzyme inhibitors in the treatment of diabetic nephropathy].
1988 • 3 citations
Ergebnisse einer 5-Jahres-Studie mit Captopril bei Patienten mit schwerer therapieresistenter Hypertonie
1986 • 2 citations
A multicenter trial of low dose captopril administered twice daily in patients with essential hypertension unresponsive to beta blocker-diuretic treatment.
1987 • 2 citations
Life quality in patients under hypotensive treatment.
1987 • 2 citations
Captopril once daily in patients with essential hypertension and hyperuricaemia.
1985 • 2 citations
Use of angiotensin I to II converting enzyme inhibitor S.Q. 14225 (captopril), in moderate essential hypertension.
1983 • 2 citations
(1) The Interaction of Renin-Angiotensin-Aldosterone System and Renal Depressor System
1982 • 2 citations
Responses of the kallikrein-kinin system to angiotensin converting enzyme inhibitors in the rat.
1984 • 2 citations
Effects of captopril on blood pressure and renin-angiotensin-aldosterone system in hypertensive subjects after inhibition of renal vasodilative system.
1984 • 2 citations
Angiotensin-converting enzyme inhibition: a new medical therapy for hypertension?
1978 • 2 citations
Converting-enzyme inhibitor administration lowers urinary free 19-nor-deoxycorticosterone levels.
1985 • 2 citations
Captopril in hypertension after renal transplantation.
1984 • 2 citations
[Long-term treatment with captopril in arterial hypertension complicated by renal failure].
1982 • 1 citations
[Treatment of essential arterial hypertension in the elderly with low-dose captopril and hydrochlorothiazide. Long-term study].
1987 • 1 citations
[Agranulocytosis caused by captopril].
1987 • 1 citations
Acute and chronic effects of captopril therapy in patients with refractory heart failure.
1982 • 1 citations
Serum potassium concentrations after initiation of captopril therapy.
1986 • 1 citations
Relation Between Urinary Kallikrein Excretion and Blood Pressure Response to a Single Oral dose of Captopril
1987 • 1 citations
ACE inhibitors: enalapril and captopril compared.
1985 • 1 citations
[Therapy of severe chronic cardiac congestive insufficiency with captopril. Short and long-term clinical, hemodynamic and biological effects].
1982 • 1 citations
[Effect of the angiotensin I-converting enzyme inhibitor captopril in hypertensive diabetics without nephropathy].
1988 • 1 citations