Enalapril

A new class of angiotensin-converting enzyme inhibitors

1980 • 704 citations

Sustained Effectiveness of Converting-Enzyme Inhibition in Patients with Severe Congestive Heart Failure

1980 • 380 citations

Immediate and sustained hemodynamic and clinical improvement in chronic heart failure by an oral angiotensin-converting enzyme inhibitor.

1980 • 291 citations

Antihypertensive therapy with MK 421: angiotensin II--renin relationships to evaluate efficacy of converting enzyme blockade.

1982 • 243 citations

Reversal of left ventricular hypertrophy in hypertensive patients treated with methyldopa

1982 • 235 citations

Enalapril maleate and a lysine analogue (MK‐521): disposition in man.

1982 • 213 citations

The Relationship of Blood Pressure to Diet and Lifestyle in Two Religious Populations

1983 • 153 citations

Three new long-acting converting-enzyme inhibitors: Relationship between plasma converting-enzyme activity and response to angiotensin I

1981 • 146 citations

The physiological disposition and metabolism of enalapril maleate in laboratory animals.

1982 • 134 citations

Pharmacodynamics of converting enzyme inhibition: the cardiovascular, endocrine and autonomic effects of MK421 (enalapril) and MK521.

1982 • 119 citations

Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects

2004 • 114 citations

An overview of the clinical pharmacology of enalapril.

1984 • 113 citations

Review of the Overall Experience of Captopril in Hypertension

1984 • 110 citations

Enalapril maleate and a lysine analogue (MK‐521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system.

1982 • 109 citations

LOW-DOSE CAPTOPRIL IN CHRONIC HEART FAILURE: ACUTE HAEMODYNAMIC EFFECTS AND LONG-TERM TREATMENT

1980 • 104 citations

Pharmacokinetics of repeated single oral doses of enalapril maleate (mk‐421) in normal volunteers

1984 • 88 citations

Effects of enalapril, a new converting enzyme inhibitor, in hypertension

1982 • 83 citations

Non-sulfhydryl-containing angiotensin-converting enzyme inhibitor (MK421): evidence for role of renin system in normotensive subjects.

1981 • 70 citations

Enalapril in essential hypertension: a comparative study with propranolol. Enalapril in Hypertension Study Group (UK).

1984 • 68 citations

Enalapril (MK421) and its lysine analogue (MK521): a comparison of acute and chronic effects on blood pressure, renin‐angiotensin system and sodium excretion in normal man.

1984 • 65 citations

Comparison of oral MK 421 and propranolol in mild to moderate essential hypertension and their effects on arterial and venous vessels of the forearm

1984 • 65 citations

Role of Angiotensin Converting Enzyme Inhibitors in Essential and Renal Hypertension

1984 • 64 citations

Increased renal plasma flow in long-term enalapril treatment of hypertension

1983 • 57 citations

Cardioprotective Effects of Enalapril in Acute Myocardial Ischemia

1984 • 52 citations

Overall tolerance and safety of enalapril.

1984 • 52 citations

Haemodynamic, hormonal, and electrolyte effects of enalapril in heart failure.

1983 • 51 citations

Time Course and Effect of Sodium Intake on Vascular and Hormonal Responses to Enalapril (MK 421) in Normal Subjects

1983 • 49 citations

Cardiac and haemodynamic effects of enalapril.

1983 • 48 citations

Long-term haemodynamic effects of enalapril (alone and in combination with hydrochlorothiazide) at rest and during exercise in essential hypertension.

1984 • 43 citations

Effect of Dietary Sodium on Angiotensin-converting Enzyme (ACE) Inhibition and the Acute Hypotensive Effect of Enalapril (MK-421) in Essential Hypertension

1984 • 42 citations

Converting-enzyme inhibitor enalapril (MK421) in treatment of hypertension with renal artery stenosis.

1982 • 39 citations

Efficacy of captopril in low-renin congestive heart failure: Importance of sustained reactive hyperreninemia in distinguishing responders from nonresponders

1984 • 38 citations

Enalapril (MK421) in the treatment of hypertension with renal artery stenosis.

1983 • 37 citations

A Comparison of Minoxidil and Hydralazine in Non-azotemic Hypertensives

1983 • 36 citations

"Scalded mouth" caused by angiotensin-converting-enzyme inhibitors.

1982 • 34 citations

Hemodynamic and antihypertensive effects of the new oral angiotensin-converting-enzyme inhibitor MK-421 (enalapril).

1984 • 32 citations

Enalapril and Lisinopril in Renovascular Hypertension Antihypertensne and Hormonal Effects of Two New Angio-Tensin-Converting-Enzyme (ACE) Inhibitors

1984 • 29 citations

Resolution of Captopril‐Induced Rash After Substitution of Enalapril

1983 • 29 citations

The Therapeutic use of a new Potassium-Sparing Diuretic, Amiloride, and a Converting Enzyme Inhibitor, Mk-421, in Preventing Hypokalemia Associated with Primary and Secondary Hyperaldosteronism

1983 • 23 citations

Mechanism for Hypotensive Action of Angiotensin Converting Enzyme Inhibitors

1984 • 23 citations

Kinetic and metabolic aspects of enalapril action.

1984 • 22 citations

Effective dose range of enalapril in mild to moderate essential hypertension.

1985 • 19 citations

A new method for the determination of d- and l-propranolol in human serum

1982 • 19 citations

A Simplified Radioimmunoassay for Physiologically Active Angiotensin Peptides [(1-8) Octa- and (2-8) Heptapeptides]

1984 • 17 citations

Contrasting renal haemodynamic responses to the angiotensin converting enzyme inhibitor enalapril and the beta-adrenergic antagonist metoprolol in essential hypertension.

1984 • 15 citations

Systemic and renal effects of enalapril and its effects on cardiac mass.

1984 • 14 citations

Acute haemodynamic, hormonal and electrolyte effects and short-term clinical response to enalapril in heart failure.

1983 • 12 citations

Effect of indoramin, labetalol and alinidine on sympathetic function in normal man.

1984 • 10 citations

Coronary Vascular Actions of the Converting Enzyme Inhibitor, Enalapril

1984 • 7 citations

Effect of antihypertensive therapy on left ventricular function and myocardial perfusion at rest and during exercise.

1984 • 6 citations

The effect of enalapril on serum prolactin.

1983 • 5 citations

Dopaminergic Control of Aldosterone Secretion in Hypertensive Patients Chronically Treated with an Angiotensin Converting Enzyme Inhibitor

1986 • 5 citations

Erythrocyte co transport in white and black hypertensive subjects

1982 • 1 citations