Neuregulin-1 proteins in rat brain and transfected cells are localized to lipid rafts

Functional rafts in cell membranes

1997 • 9,471 citations

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

1984 • 3,959 citations

FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES

1998 • 2,942 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 2,905 citations

Aggresomes: A Cellular Response to Misfolded Proteins

1998 • 2,116 citations

Multiple essential functions of neuregulin in development

1995 • 1,236 citations

Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

1993 • 961 citations

Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons

1988 • 739 citations

Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

1996 • 526 citations

The postsynaptic density at glutamatergic synapses

1997 • 474 citations

Neuregulins and Their Receptors: A Versatile Signaling Module in Organogenesis and Oncogenesis

1997 • 471 citations

A detergent-insoluble membrance compartment contains Aβ in vivo

1998 • 394 citations

Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors

1997 • 394 citations

Isoform-specific expression and function of neuregulin

1997 • 384 citations

Regulation of Neuregulin Signaling by PSD-95 Interacting with ErbB4 at CNS Synapses

2000 • 376 citations

EphrinB Ligands Recruit GRIP Family PDZ Adaptor Proteins into Raft Membrane Microdomains

1999 • 345 citations

Expression of Neuregulins and their Putative Receptors, ErbB2 and ErbB3, Is Induced during Wallerian Degeneration

1997 • 329 citations

Cysteine-Rich Domain Isoforms of the Neuregulin-1 Gene Are Required for Maintenance of Peripheral Synapses

2000 • 309 citations

GFRα-Mediated Localization of RET to Lipid Rafts Is Required for Effective Downstream Signaling, Differentiation, and Neuronal Survival

2000 • 307 citations

ARIA: A Neuromuscular Junction Neuregulin

1997 • 279 citations

The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses

2000 • 261 citations

Neuregulin-β induces expression of an NMDA-receptor subunit

1997 • 261 citations

Tyrosine Kinase Receptors Concentrated in Caveolae-like Domains from Neuronal Plasma Membrane

1997 • 248 citations

Raft association of SNAP receptors acting in apical trafficking in Madin–Darby canine kidney cells

1999 • 242 citations

Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.

1996 • 228 citations

Structural and Functional Aspects of the Multiplicity of Neu Differentiation Factors

1994 • 220 citations

Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.

1994 • 180 citations

Role of neuregulins in glial cell development

2000 • 175 citations

Caveolae, Plasma Membrane Microdomains for α-Secretase-mediated Processing of the Amyloid Precursor Protein

1998 • 157 citations

The Presence of Amyloid β-Protein in the Detergent-Insoluble Membrane Compartment of Human Neuroblastoma Cells

1998 • 150 citations

The F3 Neuronal Glycosylphosphatidylinositol‐Linked Molecule Is Localized to Glycolipid‐Enriched Membrane Subdomains and Interacts with L1 and Fyn Kinase in Cerebellum

1995 • 145 citations

A Cysteine-Rich Isoform of Neuregulin Controls the Level of Expression of Neuronal Nicotinic Receptor Channels during Synaptogenesis

1998 • 143 citations

The N-terminal Region of Neuregulin Isoforms Determines the Accumulation of Cell Surface and Released Neuregulin Ectodomain

2001 • 123 citations

Effects of GGF/neuregulins on neuronal survival and neurite outgrowth correlate with erbB2/neu expression in developing rat retina

1996 • 119 citations

Nerve Terminal Withdrawal from Rat Neuromuscular Junctions Induced by Neuregulin and Schwann Cells

1997 • 111 citations

Glycolipid‐Enriched Caveolae and Caveolae‐Like Domains in the Nervous System

1999 • 110 citations

Glial Growth Factor Rescues Schwann Cells of Mechanoreceptors from Denervation-Induced Apoptosis

1997 • 100 citations

Neurotrophic Factors Increase Neuregulin Expression in Embryonic Ventral Spinal Cord Neurons

1997 • 92 citations

Transmembrane Neuregulins Interact with LIM Kinase 1, a Cytoplasmic Protein Kinase Implicated in Development of Visuospatial Cognition

1998 • 92 citations

Domain-specific gene disruption reveals critical regulation of neuregulin signaling by its cytoplasmic tail

1998 • 92 citations

ARIA is concentrated in nerve terminals at neuromuscular junctions and at other synapses

1995 • 92 citations

Biosynthetic Processing of neu Differentiation Factor

1995 • 89 citations

Phospholipase D1 Is Phosphorylated and Activated by Protein Kinase C in Caveolin-enriched Microdomains within the Plasma Membrane

2000 • 83 citations

Neuregulin Signaling in the Heart

1999 • 73 citations

Characterization of Detergent‐Insoluble Complexes Containing the Familial Alzheimer’s Disease‐Associated Presenilins

1999 • 69 citations

Neuregulin Expression in PNS Neurons: Isoforms and Regulation by Target Interactions

1997 • 68 citations

The Neuregulin Precursor proARIA Is Processed to ARIA after Expression on the Cell Surface by a Protein Kinase C-Enhanced Mechanism

1998 • 67 citations

The N-terminal PDZ-containing region of postsynaptic density-95 mediates association with caveolar-like lipid domains

1998 • 53 citations

Roles of neuregulin in synaptogenesis between mossy fibers and cerebellar granule cells

2000 • 48 citations

Post-translational Processing of Membrane-associated neu Differentiation Factor Proisoforms Expressed in Mammalian Cells

1995 • 43 citations

The Release of Acetylcholine Receptor Inducing Activity (ARIA) from Its Transmembrane Precursor in Transfected Fibroblasts

1999 • 25 citations

Preparation of Synaptosomal Plasma Membranes by Subcellular Fractionation

2003 • 6 citations