Neuregulins with an Ig-like domain are essential for mouse myocardial and neuronal development.

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

Multiple essential functions of neuregulin in development

1995 • 1,236 citations

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

1995 • 1,130 citations

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.

1994 • 979 citations

Identification of Heregulin, a Specific Activator of p185 ^erbB2

1992 • 963 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

Genetic analysis of RXRα developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis

1994 • 684 citations

Contributions of placodal and neural crest cells to avian cranial peripheral ganglia

1983 • 684 citations

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

1994 • 632 citations

ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family

1993 • 612 citations

A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling

1994 • 601 citations

Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

1992 • 579 citations

Glial growth factor restricts mammalian neural crest stem cells to a glial fate

1994 • 496 citations

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

1993 • 469 citations

Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat schwann cell precursors

1995 • 449 citations

Heregulin induces tyrosine phosphorylation of HER4/p180erbB4

1993 • 445 citations

The erbB3 gene product is a receptor for heregulin.

1994 • 361 citations

Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice.

1994 • 325 citations

Neuregulins are concentrated at nerve-muscle synapses and activate ACh–receptor gene expression

1995 • 276 citations

Differential expression of ARIA isoforms in the rat brain

1995 • 229 citations

Structural and Functional Aspects of the Multiplicity of Neu Differentiation Factors

1994 • 220 citations

A far-downstream hepatocyte-specific control region directs expression of the linked human apolipoprotein E and C-I genes in transgenic mice.

1993 • 216 citations

Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development.

1995 • 186 citations

Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development.

1994 • 180 citations

Sensory and Motor Neuron-derived Factor. A NOVEL HEREGULIN VARIANT HIGHLY EXPRESSED IN SENSORY AND MOTOR NEURONS

1995 • 170 citations

ARIA can be released from extracellular matrix through cleavage of a heparin-binding domain.

1995 • 128 citations

The endocardial endothelium

1992 • 126 citations

Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea.

1987 • 107 citations

ARIA is concentrated in nerve terminals at neuromuscular junctions and at other synapses

1995 • 92 citations

The number of Na+ channels in cultured chick muscle is increased by ARIA, an acetylcholine receptor-inducing activity

1993 • 85 citations

Neu Differentiation Factors: A Family of Alternatively Spliced Neuronal and Mesenchymal Factors

1994 • 63 citations