The H2O2 Stimulon in Saccharomyces cerevisiae

Free radicals in biology and medicine

1991 • 17,840 citations

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Free Radicals in Biology and Medicine

1990 • 4,962 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

Free Radicals and Antioxidants: A Personal View

2009 • 1,095 citations

The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).

1996 • 1,050 citations

Characterization of the Yeast Transcriptome

1997 • 941 citations

Thioredoxin-dependent peroxide reductase from yeast.

1994 • 940 citations

Heat shock proteins: molecular chaperones of protein biogenesis

1993 • 598 citations

GENEALOGY OF PRINCIPAL STRAINS OF THE YEAST GENETIC STOCK CENTER

1986 • 587 citations

Trehalose in yeast, stress protectant rather than reserve carbohydrate

1990 • 537 citations

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4.

1996 • 475 citations

YAP1 dependent activation of TRX2 is essential for the response of Saccharomyces cerevisiae to oxidative stress by hydroperoxides.

1994 • 472 citations

Proteasomes: destruction as a programme

1996 • 373 citations

Degradation of Oxidized Proteins in K562 Human Hematopoietic Cells by Proteasome

1996 • 333 citations

Stress-induced transcriptional activation

1995 • 325 citations

The role of trehalose synthesis for the acquisition of thermotolerance in yeast

1994 • 320 citations

Bacterial defenses against oxidative stress

1990 • 316 citations

Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: genetic evidence for a stress-induced recycling of glycogen and trehalose

1997 • 306 citations

The molecular defences against reactive oxygen species in yeast

1996 • 268 citations

A yeast mutant lacking mitochondrial manganese-superoxide dismutase is hypersensitive to oxygen.

1986 • 262 citations

Redox redux: The control of oxidative stress responses

1991 • 242 citations

Importance of catalase in the adaptive response to hydrogen peroxide: analysis of acatalasaemic Saccharomyces cerevisiae

1996 • 239 citations

Saccharomyces cerevisiae has distinct adaptive responses to both hydrogen peroxide and menadione

1992 • 234 citations

Activity of Ubiquitin-dependent Pathway in Response to Oxidative Stress

1997 • 233 citations

Yeast glutathione reductase is required for protection against oxidative stress and is a target gene for yAP‐1 transcriptional regulation

1996 • 227 citations

The UV response involving the ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals

1994 • 225 citations

The Yeast Copper/Zinc Superoxide Dismutase and the Pentose Phosphate Pathway Play Overlapping Roles in Oxidative Stress Protection

1996 • 217 citations

Stress response of yeast

1993 • 211 citations

Mutants that show increased sensitivity to hydrogen peroxide reveal an important role for the pentose phosphate pathway in protection of yeast against oxidative stress

1996 • 209 citations

Inducibility of the response of yeast cells to peroxide stress

1992 • 207 citations

Functional Specificity Among Hsp70 Molecular Chaperones

1997 • 206 citations

Null mutants of Saccharomyces cerevisiae Cu,Zn superoxide dismutase: characterization and spontaneous mutation rates

1991 • 204 citations

A glutathione reductase mutant of yeast accumulates high levels of oxidized glutathione and requires thioredoxin for growth.

1996 • 188 citations

Metabolic and Regulatory Changes Associated with Growth of Saccharomyces cerevisiae in 1.4 M NaCl

1997 • 186 citations

Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase

1990 • 179 citations

Molecular Genetics of Superoxide Dismutases in Yeasts and Related Fungi

1992 • 172 citations

Oxidative stress induced heat shock factor phosphorylation and HSF-dependent activation of yeast metallothionein gene transcription.

1996 • 159 citations

Arabidopsis thaliana NADPH Oxidoreductase Homologs Confer Tolerance of Yeasts toward the Thiol-oxidizing Drug Diamide

1995 • 159 citations

Lipid Peroxidation Product, 4-Hydroxynonenal and Its Conjugate with GSH Are Excellent Substrates of Bovine Lens Aldose Reductase

1995 • 157 citations

The response regulator-like protein Pos9/Skn7 ofSaccharomyces cerevisiae is involved in oxidative stress resistance

1996 • 151 citations

Saccharomyces Cerevisiae has an Inducible Response to Menadione which differs from that to Hydrogen Peroxide

1993 • 151 citations

Aldose reductase induction: a novel response to oxidative stress of smooth muscle cells

1997 • 144 citations

Analysis of Saccharomyces cerevisiae proteins induced by peroxide and superoxide stress

1994 • 134 citations

Yap1p, a yeast transcriptional activator that mediates multidrug resistance, regulates the metabolic stress response.

1994 • 132 citations

Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.

1991 • 132 citations

Ribosomal Acidic Phosphoproteins P1 and P2 Are Not Required for Cell Viability but Regulate the Pattern of Protein Expression in Saccharomyces cerevisiae

1995 • 122 citations

Mutants of Saccharomyces cerevisiae sensitive to oxidative and osmotic stress

1995 • 106 citations

Two‐dimensional gel protein database of Saccharomyces cerevisiae

1996 • 100 citations

Neutral trehalase Nth1p of Saccharomyces cerevisiae encoded by the NTH1 gene is a multiple stress responsive protein

1997 • 83 citations

A novel essential fission yeast gene Pad1+ positively regulates Pap1+-dependent transcription and is implicated in the maintenance of chromosome structure

1995 • 75 citations

A thiol-specific antioxidant and sequence homology to various proteins of unknown function.

1994 • 75 citations

Rapid Identification of Yeast Proteins on Two-dimensional Gels

1996 • 75 citations

Two Genes Encode the Major Membrane-associated Protein Of Methanol-induced Peroxisomes from Candida boidinii

1989 • 60 citations

Pentose-phosphate pathway in Saccharomyces cerevisiae: analysis of deletion mutants for transketolase, transaldolase, and glucose 6-phosphate dehydrogenase

1993 • 41 citations

Trehalose metabolism in Saccharomyces cerevisiae during heat-shock

1994 • 36 citations

High control coefficient of transketolase in the nonoxidative pentose phosphate pathway of human erythrocytes: NMR, antibody, and computer simulation studies

1992 • 34 citations

The Ubiquitin-mediated Proteolytic System: Involvement of Molecular Chaperones, Degradation of Oncoproteins, and Activation of Transcriptional Regulators

1995 • 30 citations

Cloning and sequencing of a gene encoding yeast thioltransferase

1992 • 25 citations

Yeast thiol‐dependent protector protein expression enhances the resistance of Escherichia coli to hydrogen peroxide

1996 • 7 citations