Interaction of c-Jun Amino-terminal Kinase Interacting Protein-1 with p190 rhoGEF and Its Localization in Differentiated Neurons

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.

1993 • 1,459 citations

A Cytoplasmic Inhibitor of the JNK Signal Transduction Pathway

1997 • 678 citations

A Mammalian Scaffold Complex That Selectively Mediates MAP Kinase Activation

1998 • 653 citations

Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.

1994 • 617 citations

An Alternative to SH2 Domains for Binding Tyrosine-Phosphorylated Proteins

1994 • 501 citations

Regulation of Dendritic Growth and Remodeling by Rho, Rac, and Cdc42

1997 • 493 citations

The Phosphotyrosine Interaction Domains of X11 and FE65 Bind to Distinct Sites on the YENPTY Motif of Amyloid Precursor Protein

1996 • 480 citations

Role of Actin Polymerization and Adhesion to Extracellular Matrix in Rac- and Rho-induced Cytoskeletal Reorganization

1997 • 378 citations

Phosphotyrosine-Dependent Interaction of SHC and Insulin Receptor Substrate 1 with the NPEY Motif of the Insulin Receptor via a Novel Non-SH2 Domain

1995 • 368 citations

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

1995 • 361 citations

Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation

1998 • 341 citations

A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.

1994 • 334 citations

[34] Ras-Raf interaction: Two-hybrid analysis

1995 • 287 citations

Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.

1996 • 280 citations

Rho family GTPases: the cytoskeleton and beyond

1996 • 262 citations

Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action.

1993 • 210 citations

Myelin and Collapsin-1 Induce Motor Neuron Growth Cone Collapse through Different Pathways: Inhibition of Collapse by Opposing Mutants of Rac1

1999 • 184 citations

Dissociation of LPA-induced cytoskeletal contraction from stress fiber formation by differential localization of RhoA

1997 • 155 citations

Identification of a Novel, Putative Rho-specific GDP/GTP Exchange Factor and a RhoA-binding Protein: Control of Neuronal Morphology

1997 • 154 citations

The Dbl-related Protein, Lfc, Localizes to Microtubules and Mediates the Activation of Rac Signaling Pathways in Cells

1999 • 153 citations

IB1, a JIP-1-related Nuclear Protein Present in Insulin-secreting Cells

1998 • 141 citations

The Phosphotyrosine Interaction Domain of Shc Binds an LXNPXY Motif on the Epidermal Growth Factor Receptor

1995 • 137 citations

Expression of a Constitutively Active Phosphatidylinositol 3-Kinase Induces Process Formation in Rat PC12 Cells

1997 • 131 citations

Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway

1998 • 128 citations

GTPase-Deficient Gα₁₆ and Gα_q Induce PC12 Cell Differentiation and Persistent Activation of cJun NH₂-Terminal Kinases

1996 • 123 citations

The Mammalian Numb Phosphotyrosine-binding Domain

1998 • 118 citations

Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1

1998 • 113 citations

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.

1996 • 104 citations

Specific Activation of a c-Jun NH2-terminal Kinase Isoform and Induction of Neurite Outgrowth in PC-12 Cells by Staurosporine

1997 • 96 citations

Numb-Associated Kinase Interacts with the Phosphotyrosine Binding Domain of Numb and Antagonizes the Function of Numb In Vivo

1998 • 71 citations

Functional Analysis of the Numb Phosphotyrosine-binding Domain Using Site-directed Mutagenesis

1998 • 40 citations

Identification of Residues within the SHC Phosphotyrosine Binding/Phosphotyrosine Interaction Domain Crucial for Phosphopeptide Interaction

1996 • 36 citations

Genomic Organization, Fine-Mapping, and Expression of the HumanIslet-Brain 1 (IB1)/C-Jun-Amino-Terminal Kinase Interacting Protein-1 (JIP-1)Gene

1999 • 30 citations