Normal clonal expansion but impaired Fasmediated cell death and anergy induction in interleukin‐2‐deficient mice

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

1988 • 1,086 citations

lnterleukin-2 programs mouse αβ T lymphocytes for apoptosis

1991 • 1,027 citations

Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain

1995 • 1,024 citations

Fas and Fas ligand: lpr and gld mutations

1995 • 906 citations

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

1991 • 892 citations

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

1995 • 868 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

1995 • 616 citations

Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. Functional and morphological studies.

1987 • 592 citations

Immune Responses in Interleukin-2-Deficient Mice

1993 • 476 citations

Activation interferes with the APO-1 pathway in mature human T cells

1993 • 466 citations

Dead cell discrimination with 7‐amino‐actinomcin D in combination with dual color immunofluorescence in single laser flow cytometry

1992 • 443 citations

Helper T‐Cell Subsets: Phenotype, Function and the Role of Lymphokines in Regulating their Development

1991 • 423 citations

In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B.

1990 • 370 citations

CTLA4 mediates antigen-specific apoptosis of human T cells.

1995 • 331 citations

Selective anergy of V beta 8+,CD4+ T cells in Staphylococcus enterotoxin B-primed mice.

1990 • 312 citations

The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo

1994 • 291 citations

Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing Vβ8 TCR: a role of the Qa-1 molecule

1995 • 175 citations

Development and proliferation of lymphocytes in mice deficient for both interleukins‐2 and ‐4

1994 • 146 citations

Recovery from autoimmunity of MRL/lpr mice after infection with an interleukin-2/vaccinia recombinant virus

1990 • 140 citations

Expression and function of mouse Fas antigen on immature and mature T cells.

1995 • 133 citations

Molecular Genetics of Murine Lupus Models

1989 • 129 citations

Fatal interactions: fas-induced apoptosis of mature T cells

1994 • 118 citations

Memory T cells are anergic to the superantigen staphylococcal enterotoxin B.

1992 • 92 citations

Peripheral T‐Cell Reactivity to Bacterial Superantigens in vivo: The Response/Anergy Paradox

1993 • 71 citations

Expansion and clonal deletion of peripheral T cells induced by bacterial superantigen is independent of the interleukin‐2 pathway

1992 • 70 citations

Antigen-reactive cloned helper T cells. II. Exposure of murine cloned helper T cells to IL 2-containing supernatant induces unresponsiveness to antigenic restimulation and inhibits lymphokine production after antigenic stimulation.

1984 • 51 citations

New advances on cytokines

1993 • 25 citations

Induction of unresponsiveness to the superantigen staphylococcal enterotoxin B: cyclosporin A resistant split unresponsiveness unfolds in vivo without preceding clonal expansion

1993 • 23 citations

Overexpression and knockout of cytokines in transgenic mice.

1994 • 20 citations

Insights into autoimmunity: from classical models to current perspectives.

1990 • 16 citations

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