Localization of the apoptosis-inducing activity of lupus anticoagulant in an annexin V-binding antibody subset.

The 1982 revised criteria for the classification of systemic lupus erythematosus

1982 • 14,553 citations

Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins

1994 • 1,113 citations

Apoptotic Vascular Endothelial Cells Become Procoagulant

1997 • 612 citations

Lupus Anticoagulant IgG's (LA) Are Not Directed to Phospholipids only, but to a Complex of Lipid-Bound Human Prothrombin

1991 • 583 citations

Obstetric Complications Associated with the Lupus Anticoagulant

1985 • 568 citations

Thrombosis, Recurrent Fetal Loss, and Thrombocytopenia

1986 • 554 citations

The Annexins and Exocytosis

1992 • 549 citations

Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.

1994 • 535 citations

Pregnancy Loss in the Antiphospholipid-Antibody Syndrome — A Possible Thrombogenic Mechanism

1997 • 525 citations

Immunology and Clinical Importance of Antiphospholipid Antibodies

1991 • 490 citations

Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus.

1996 • 485 citations

Anti-phospholipid Antibodies

1985 • 454 citations

Activation of cultured vascular endothelial cells by antiphospholipid antibodies.

1995 • 425 citations

Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other "antiphospholipid" autoantibodies [see comments]

1994 • 364 citations

"Anticardiolipin" autoantibodies recognize beta 2-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding.

1995 • 337 citations

Phospholipid binding properties of human placental anticoagulant protein-I, a member of the lipocortin family

1989 • 312 citations

Immunology of the antiphospholipid antibody syndrome

1996 • 311 citations

“Lupus” Anticoagulant and Thrombosis – Possible Role of Inhibition of Prostacyclin Formation

1982 • 300 citations

The Frequency of Lupus Anticoagulant in Systemic Lupus Erythematosus

1987 • 240 citations

β2-glycoprotein-I (apolipoprotein H) interactions with phospholipid vesicles

1984 • 234 citations

Annexin V, the regulator of phosphatidylserine-catalyzed inflammation and coagulation during apoptosis

1997 • 234 citations

Human placental anticoagulant protein: isolation and characterization

1987 • 228 citations

Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies

1990 • 216 citations

The Complexity of the Phospholipid Binding Protein Annexin V

1995 • 215 citations

Calcium-activated endonexin II forms calcium channels across acidic phospholipid bilayer membranes.

1990 • 213 citations

Binding and Phagocytosis of Apoptotic Vascular Smooth Muscle Cells Is Mediated in Part by Exposure of Phosphatidylserine

1995 • 208 citations

Antibodies to β2-glycoprotein I and clinical manifestations in patients with systemic lupus erythematosus

1996 • 202 citations

Antiphospholipid antibody syndrome: Immunologic and clinical aspects

1990 • 199 citations

Effect of Lupus Anticoagulant on Antithrombogenic Properties of Endothelial Cells - Inhibition of Thrombomodulin-Dependent Protein C Activation

1988 • 194 citations

Isolation and partial purification of a novel anticoagulant from arteries of human umbilical cord

1985 • 187 citations

Induction of endothelial cell tissue factor activity by sera from patients with antiphospholipid syndrome: A possible mechanism of thrombosis

1993 • 148 citations

Inhibition of protein kinase C by annexin V

1992 • 148 citations

Prekallikrein Inhibition Associated with the Lupus Anticoagulant: A Mechanism of Thrombosis

1982 • 146 citations

Structure and Expression of cDNA for an Inhibitor of Blood Coagulation Isolated from Human Placenta: A New Lipocortin-Like Protein

1987 • 146 citations

Antiphospholipid Antibodies Enhance Thrombin-Induced Platelet Activation and Thromboxane Formation

1993 • 140 citations

On the role of phosphatidylethanolamine in the inhibition of activated protein C activity by antiphospholipid antibodies.

1995 • 132 citations

Antiphospholipid-protein antibodies: Laboratory detection and clinical relevance

1995 • 131 citations

An IgM Lupus Anticoagulant that Neutralizes the Enhancing Effect of Phospholipid on Purified Endothelial Thrombomodulin Activity-A Mechanism for Thrombosis

1986 • 130 citations

Inhibition of Cytosolic Phospholipase A2 by Annexin V in Differentiated Permeabilized HL-60 Cells

1997 • 106 citations

Similarity in calcium channel activity of annexin V and matrix vesicles in planar lipid bilayers

1996 • 96 citations

ANTIPHOSPHOLIPID ANTIBODIES

1990 • 92 citations

Comparison of an enzyme‐linked immunosorbent assay for antibodies to β₂‐glycoprotein I and a conventional anticardiolipin immunoassay

1996 • 90 citations

Reactivity to beta 2 glycoprotein I clearly differentiates anticardiolipin antibodies from antiphospholipid syndrome and syphilis.

1996 • 85 citations

Thrombosis, recurrent fetal loss, and thrombocytopenia. Predictive value of the anticardiolipin antibody test

1986 • 84 citations

Inhibition of Arterial Thrombosis by Recombinant Annexin V in a Rabbit Carotid Artery Injury Model

1997 • 84 citations

Sedimentation equilibrium analysis of five lipocortin-related phospholipase A2 inhibitors from human placenta. Evidence against a mechanistically relevant association between enzyme and inhibitor.

1988 • 82 citations

Lupus anticoagulant induces a selective defect in thrombin‐mediated endothelial prostacyclin release and platelet aggregation

1989 • 75 citations

Impaired Fibrinolysis as an Essential Contribution to Thrombosis in Patients with Lupus Anticoagulant

1989 • 73 citations

Lupus Anticoagulant Autoantibody Induces Apoptosis in Umbilical Vein Endothelial Cells: Involvement of Annexin V

1994 • 72 citations

Antiendothelial Cell Antibodies in Patients with the Antiphospholipid Syndrome

1991 • 71 citations

Binding of recombinant annexin V to endothelial cells: effect of annexin V binding on endothelial-cell-mediated thrombin formation

1994 • 63 citations

Antiphospholipid Antibodies: Proposed Mechanisms of Action

1992 • 56 citations

Impairment of the protein C anticoagulant pathway in a patient with systemic lupus erythematosus, anticardiolipin antibodies and thrombosis

1990 • 55 citations

Antiphospholipid antibodies and thrombotic predisposition: underlying pathogenetic mechanisms [editorial; comment]

1994 • 54 citations

Studies on phospholipid antibodies, APC-resistance and associated mutation in the coagulation factor V gene

1995 • 50 citations

Non β₂-Glycoprotein I Cofactors for Antiphospholipid Antibodies

1996 • 45 citations

Differences in the Interactions of Lupus Anticoagulant IgG with Human Prothrombin and Bovine Prothrombin

1995 • 44 citations

Antibody to annexin V has anti‐phospholipid and lupus anticoagulant properties

1995 • 44 citations

Annexin V inhibits the procoagulant activity of matrices of TNF-stimulated endothelium under blood flow conditions.

1994 • 42 citations

Lupus anticoagulant--antiphospholipid antibodies and thrombophilia. Relation to protein C--protein S--thrombomodulin.

1990 • 41 citations

Inhibitory Effect of Annexin V on Protein Kinase C Activity in Mesangial Cell Lysates

1995 • 32 citations

Presence and Comparison of Ca2+Transport Activity of Annexins I, II, V, and VI in Large Unilamellar Vesicles

1997 • 31 citations

Annexin V perturbs or stabilises phospholipid membranes in a calcium‐dependent manner

1995 • 27 citations

Fas antigen and bcl-2 expression on lymphocytes cultured with cytomegalovirus and varicella—zoster virus antigen

1995 • 26 citations

Obstetric complications associated with the lupus anticoagulant

1986 • 22 citations

Decreased fibrinolytic capacity and increased von Willebrand factor levels as indicators of endothelial cell dysfunction in patients with lupus anticoagulant

1989 • 18 citations

The lupus anticoagulant and eicosanoids

1993 • 16 citations

Absence of cell-surface annexin V is accompanied by defective collagen matrix binding in the swarm rat chondrosarcoma

1997 • 15 citations

Partial coverage of phospholipid model membranes with annexin V may completely inhibit their degradation by phospholipase A₂

1997 • 14 citations

Studies on the interaction of placental anticoagulant protein I, β2glycoprotein 1, and antiphospholipid antibodies in the prothrombinase reaction and in the solid phase anticardiolipin assays

1996 • 13 citations

Heterogeneity and Diversity of IgM and IgG Lupus Anticoagulants in an Individual with Systemic Lupus Erythematosus

1994 • 11 citations

Inhibitors of platelet aggregation and blood coagulation isolated from the human placenta

1984 • 10 citations