Inhibitory Effect of Annexin V on Protein Kinase C Activity in Mesangial Cell Lysates

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Protein kinase C isoenzymes: divergence in signal transduction?

1993 • 1,237 citations

[1] Assays of protein kinase

1983 • 832 citations

Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

1990 • 654 citations

Inhibition of phospholipase A2 by "lipocortins" and calpactins. An effect of binding to substrate phospholipids.

1987 • 534 citations

PKCu is a novel, atypical member of the protein kinase C family.

1994 • 519 citations

Identification of intracellular receptor proteins for activated protein kinase C.

1991 • 505 citations

14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins

1992 • 483 citations

Protein kinase C, calcium and phospholipid degradation

1992 • 400 citations

Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells.

1993 • 352 citations

Characterization of lipocortin I and an immunologically unrelated 33-kDa protein as epidermal growth factor receptor/kinase substrates and phospholipase A2 inhibitors.

1987 • 265 citations

Novel anti-inflammatory peptides from the region of highest similarity between uteroglobin and lipocortin I

1988 • 244 citations

Sequential activation and lethal hit measured by [Ca2+]i in individual cytolytic T cells and targets.

1987 • 231 citations

Human placental anticoagulant protein: isolation and characterization

1987 • 228 citations

Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide

1989 • 220 citations

Protein kinase C inhibitor proteins

1990 • 213 citations

Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzyme

1991 • 212 citations

Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.

1989 • 204 citations

The protein-tyrosine kinase substrate p36 is also a substrate for protein kinase C in vitro and in vivo.

1986 • 204 citations

Characterization of specific binding sites for [3H]-staurosporine on various protein kinases

1990 • 164 citations

Inhibition of protein kinase C by annexin V

1992 • 148 citations

Sub-domain structure of lipid-bound annexin-V resolved by electron image analysis

1991 • 141 citations

Primary structure of human placental anticoagulant protein

1987 • 132 citations

Lipocortin inhibition of extracellular and intracellular phospholipases A₂ is substrate concentration dependent

1987 • 115 citations

Cloning and expression of cDNA for human vascular anticoagulant, a Ca²⁺‐dependent phospholipid‐binding protein

1988 • 99 citations

Cloning and expression of cDNA for human endonexin II, a Ca2+ and phospholipid binding protein.

1988 • 98 citations

Annexin V forms calcium‐dependent trimeric units on phospholipid vesicles

1992 • 95 citations

Annexin‐I inhibits phospholipase A₂ by specific interaction, not by substrate depletion

1994 • 90 citations

Possible regulatory functions of protein kinase C-α and -ε isoenzymes in rat renal mesangial cells. Stimulation of prostaglandin synthesis and feedback inhibition of angiotensin II-stimulated phosphoinositide hydrolysis

1991 • 87 citations

In vitro protein kinase C phosphorylation sites of placental lipocortin

1988 • 83 citations

Sedimentation equilibrium analysis of five lipocortin-related phospholipase A2 inhibitors from human placenta. Evidence against a mechanistically relevant association between enzyme and inhibitor.

1988 • 82 citations

A purified lipocortin shares the anti‐inflammatory effect of glucocorticosteroids in vivo in mice

1989 • 78 citations

Phosphorylation of lipocortins invitro by protein kinase C

1986 • 75 citations

Immunocharacterization of δ‐ and ζ‐isoenzymes of protein kinase C in rat renal mesangial cells

1992 • 67 citations

Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies.

1986 • 64 citations

Annexin 5 as a potential regulator of annexin 1 phosphorylation by protein kinase C. In vitro inhibition compared with quantitative data on annexin distribution in human endothelial cells

1993 • 53 citations

DNA measurement by mithramycin fluorescence in chromatin solubilized by heparin

1980 • 49 citations

Further characterization of four lipocortins from human peripheral blood mononuclear cells

1989 • 35 citations

Protein kinase C-dependent phosphorylation of annexins I and II in mesangial cells

1993 • 31 citations

Calphobindins (Placental Annexins) Inhibit Protein Kinase C

1992 • 26 citations

Identification of four lipocortin proteins and phosphorylation of lipocortin I by protein kinase C in cytosols of porcine thyroid cell cultures

1989 • 23 citations

Immunological identification of protein kinase C-α and protein kinase C-δ in cultured rat mesangial cells: Diffferential sensitivity of the two isoforms towards the protein kinase inhibitor H7

1992 • 13 citations

Effect of UV light on small nuclear RNA synthesis: increased inhibition during postirradiation cell incubation.

1986 • 12 citations

Heterogeneity of protein kinase C in cultured rat mesangial cells

1992 • 5 citations