The lupus anticoagulant and eicosanoids

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

1990 • 1,618 citations

ANTICARDIOLIPIN ANTIBODIES: DETECTION BY RADIOIMMUNOASSAY AND ASSOCIATION WITH THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS

1983 • 1,413 citations

Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor

1990 • 1,294 citations

Platelet Activation in Unstable Coronary Disease

1986 • 1,161 citations

Antiphospholipid Antibodies: Anticardiolipin and the Lupus Anticoagulant in Systemic Lupus Erythematosus (SLE) and in Non-SLE Disorders

1990 • 1,093 citations

Anticardiolipin syndrome

2011 • 852 citations

Antibody to Cardiolipin as a Predictor of Fetal Distress or Death in Pregnant Patients with Systemic Lupus Erythematosus

1985 • 594 citations

Lupus Anticoagulant IgG's (LA) Are Not Directed to Phospholipids only, but to a Complex of Lipid-Bound Human Prothrombin

1991 • 583 citations

ARTERIAL THROMBOSIS, INTRAUTERINE DEATH AND "LUPUS" ANTICOAGULANT: DETECTION OF IMMUNOGLOBULIN INTERFERING WITH PROSTACYCLIN FORMATION

1981 • 558 citations

Measurement of anti-cardiolipin antibodies by an enzyme-linked immunosorbent assay (ELISA): standardization and quantitation of results.

1985 • 554 citations

Acquired inhibitors of blood coagulation.

1972 • 531 citations

THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS DESPITE CIRCULATING ANTICOAGULANTS.

1963 • 524 citations

Thrombosis in Patients with the Lupus Anticoagulant

1980 • 511 citations

Increased Prostacyclin Biosynthesis in Patients with Severe Atherosclerosis and Platelet Activation

1984 • 510 citations

A hemorrhagic disorder caused by circulating anticoagulant in patients with disseminated lupus erythematosus

1952 • 499 citations

A clinical study of the lupus anticoagulant

1976 • 478 citations

UNSTABLE METABOLITES OF ARACHIDONIC ACID AND THEIR ROLE IN HAEMOSTASIS AND THROMBOSIS

1978 • 447 citations

The Anticardiolipin Syndrome

1987 • 433 citations

The Second International Anti-Cardiolipin Standardization Workshop/The Kingston Anti-Phospholipid Antibody Study (KAPS) Group

1990 • 420 citations

Decidual vasculopathy and extensive placental infarction in a patient with repeated thromboembolic accidents, recurrent fetal loss, and a lupus anticoagulant

1982 • 414 citations

Monoclonal immunoglobulin M lambda coagulation inhibitor with phospholipid specificity. Mechanism of a lupus anticoagulant.

1980 • 367 citations

SI CHAOS

1976 • 363 citations

Thrombosis and haemostasis

1988 • 327 citations

Thromboembolism in Patients With the 'Lupus'-Type Circulating Anticoagulant

1984 • 312 citations

“Lupus” Anticoagulant and Thrombosis – Possible Role of Inhibition of Prostacyclin Formation

1982 • 300 citations

11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation.

1986 • 281 citations

Prednisone does not prevent recurrent fetal death in women with antiphospholipid antibody

1989 • 267 citations

The Relationship Between Lupus Anticoagulants and Antibodies to Phospholipid

1988 • 254 citations

Presence of complement-fixing anti-endothelial cell antibodies in systemic lupus erythematosus.

1984 • 253 citations

Guidelines for testing and revised criteria for lupus anticoagulants. SSC Subcommittee for the Standardization of Lupus Anticoagulants.

1991 • 249 citations

Immune mediated mechanism for thrombosis: antiphospholipid antibody binding to platelet membranes.

1988 • 226 citations

Lupus Anticoagulants and Thrombosis

1985 • 197 citations

Effect of Lupus Anticoagulant on Antithrombogenic Properties of Endothelial Cells - Inhibition of Thrombomodulin-Dependent Protein C Activation

1988 • 194 citations

Immunological specificity and mechanism of action of IgG lupus anticoagulants

1987 • 193 citations

Guidelines for Testing and Revised Criteria for Lupus Anticoagulants

1991 • 192 citations

Anticoagulant Activity of β2-Glycoprotein I Is Potentiated by a Distinct Subgroup of Anticardiolipin Antibodies

1992 • 183 citations

Lupus anticoagulant activity is frequently dependent on the presence of beta 2-glycoprotein I.

1992 • 175 citations

Anticardiolipin antibodies associated with HTLV‐III infection

1987 • 169 citations

Anticardiolipin antibodies and lupus anticoagulants comprise separate antibody subgroups with different phospholipid binding characteristics

1989 • 159 citations

The lupus anticoagulant

1976 • 145 citations

Lupus Anticoagulant Activity Is Frequently Dependent on the Presence of β2-Glycoprotein I

1992 • 142 citations

“LUPUS” ANTICOAGULANT AND INHIBITION OF PROSTACYCLIN FORMATION IN PATIENTS WITH REPEATED ABORTION, INTRAUTERINE GROWTH RETARDATION AND INTRAUTERINE DEATH

1981 • 140 citations

Imbalance of thromboxane/prostacyclin biosynthesis in patients with lupus anticoagulant

1991 • 127 citations

Distinguishing Plasma Lupus Anticoagulants from Anti-Factor Antibodies Using Hexagonal (II) Phase Phospholipids

1989 • 111 citations

Phospholipid-Binding Antibodies

2020 • 109 citations

Lupus anticoagulants: misnomer, paradox, riddle, epiphenomenon.

1988 • 101 citations

Biosynthesis of thromboxane in patients with systemic sclerosis and Raynaud's phenomenon.

1986 • 89 citations

Separation of anticardiolipin antibodies from lupus anticoagulant on a phospholipid-coated polystyrene column

1988 • 83 citations

Thrombosis Associated with Antiphospholipid Antibodies Cannot Be Explained by Effects on Endothelial and Platelet Prostanoid Synthesis

1988 • 82 citations

Evaluation of lupus anticoagulants: Antiphospholipid antibodies, endothelium associated immunoglobulin, endothelial prostacyclin secretion, and antigenic protein S levels

1988 • 75 citations

Lupus anticoagulant induces a selective defect in thrombin‐mediated endothelial prostacyclin release and platelet aggregation

1989 • 75 citations

Lupus anticoagulant inhibition of in Vitro prostacyclin release is associated with a thrombosis-prone subset of patients

1991 • 69 citations

Immunologic Disease and Fetal Death

1987 • 66 citations

Thromboembolism in patients with the 'lupus'-type circulating anticoagulant

1984 • 58 citations

Thromboxane A2 analogue (U-46619) stimulates vascular PGI2 synthesis

1985 • 52 citations

The relationship between lupus anticoagulants and antibodies to phospholipid

1988 • 48 citations

Increased thromboxane formation in patients with antiphospholipid syndrome

1990 • 41 citations

Some antiphospholipid antibodies inhibit phospholipase A2 activity.

1992 • 40 citations

Clinical Significance of Various ELISA Assays for Detecting Antiphospholipid Antibodies

1990 • 26 citations

Evaluation of the clinical and laboratory associations of antiphosphatidylethanolamine antibodies

1990 • 24 citations

The lupus anticoagulant stimulates the release of prostacyclin from human endothelial cells

1988 • 23 citations

Separation of Lupus Anticoagulant from Anticardiolipin Antibodies by Ion-Exchange and Gel Filtration Chromatography

1991 • 20 citations

Comparison of Various Screening and Confirmatory Tests for the Detection of the Lupus Anticoagulant

1990 • 18 citations

Polyfunctional properties of hybridoma lupus anticoagulant antibodies.

1987 • 12 citations

PRESENCE OF THE LUPUS ANTICOAGULANT IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS DOES NOT CAUSE INHIBITION OF PROSTACYCLIN PRODUCTION

1987 • 9 citations

Selective inhibition of platelet-derived thromboxane A2 in patients with lupus anticoagulant using low doses aspirin as assessed by enzyme immunoassay.

1991 • 5 citations