Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

2003 • 1,925 citations

The neuropathology of schizophrenia

1999 • 1,664 citations

Neuregulin 1 and Susceptibility to Schizophrenia

2002 • 1,654 citations

Schizophrenia: a disconnection syndrome?

1995 • 1,310 citations

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

2001 • 1,194 citations

Schizophrenia as a Disorder of Neurodevelopment

2002 • 1,137 citations

GABAergic Interneurons Implications for Understanding Schizophrenia and Bipolar Disorder

2001 • 1,080 citations

Mice with Reduced NMDA Receptor Expression Display Behaviors Related to Schizophrenia

1999 • 1,063 citations

Oligodendrocyte dysfunction in schizophrenia and bipolar disorder

2003 • 911 citations

Molecular Characterization of Schizophrenia Viewed by Microarray Analysis of Gene Expression in Prefrontal Cortex

2000 • 884 citations

Catching Up on Schizophrenia

2000 • 815 citations

White Matter Changes in Schizophrenia

2003 • 794 citations

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

1993 • 744 citations

Decreased Glutamic Acid Decarboxylase67 Messenger RNA Expression in a Subset of Prefrontal Cortical γ-Aminobutyric Acid Neurons in Subjects With Schizophrenia

2000 • 690 citations

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

1995 • 676 citations

ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family

1993 • 612 citations

Association of Neuregulin 1 with Schizophrenia Confirmed in a Scottish Population

2003 • 557 citations

Neuregulin and ErbB receptor signaling pathways in the nervous system

2001 • 490 citations

Electron microscopy of oligodendroglia in severe mental illness

2001 • 482 citations

Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics

1996 • 440 citations

Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia

2003 • 418 citations

Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins

2003 • 415 citations

Maldistribution of Interstitial Neurons in Prefrontal White Matter of the Brains of Schizophrenic Patients

1996 • 391 citations

Neuregulin and erbB Receptors Play a Critical Role in Neuronal Migration

1997 • 381 citations

GGF/Neuregulin Is a Neuronal Signal That Promotes the Proliferation and Survival and Inhibits the Differentiation of Oligodendrocyte Progenitors

1996 • 374 citations

Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex

1997 • 366 citations

Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment

2003 • 335 citations

Genes, environment and schizophrenia

2001 • 305 citations

Decreased protein level of nicotinic receptor α7 subunit in the frontal cortex from schizophrenic brain

1999 • 280 citations

Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia

2003 • 275 citations

Neuregulin-β induces expression of an NMDA-receptor subunit

1997 • 261 citations

Regional Gray Matter, White Matter, and Cerebrospinal Fluid Distributions in Schizophrenic Patients, Their Siblings, and Controls

1998 • 252 citations

Neuronal Nicotinic Receptors in Dementia with Lewy Bodies and Schizophrenia

1999 • 252 citations

Association study of neuregulin 1 gene with schizophrenia

2003 • 241 citations

Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia

2003 • 239 citations

Differential expression of ARIA isoforms in the rat brain

1995 • 229 citations

GABA Transporter-1 mRNA in the Prefrontal Cortex in Schizophrenia: Decreased Expression in a Subset of Neurons

2001 • 222 citations

Neural Development of the Neuregulin Receptor ErbB4 in the Cerebral Cortex and the Hippocampus: Preferential Expression by Interneurons Tangentially Migrating from the Ganglionic Eminences

2003 • 211 citations

Recent advances in defining the neuropathology of schizophrenia

1996 • 206 citations

Molecular and cellular evidence for an oligodendrocyte abnormality in schizophrenia.

2002 • 192 citations

Schizophrenia Breakdown in the Well-regulated Lifelong Process of Brain Development and Maturation

2002 • 182 citations

Evidence that Axon-Derived Neuregulin Promotes Oligodendrocyte Survival in the Developing Rat Optic Nerve

2000 • 171 citations

Normal Female Sexual Development Requires Neuregulin–erbB Receptor Signaling in Hypothalamic Astrocytes

2003 • 170 citations

Failure of spinal cord oligodendrocyte development in mice lacking neuregulin

1999 • 165 citations

Neuregulin induces GABA(A) receptor subunit expression and neurite outgrowth in cerebellar granule cells.

1999 • 160 citations

Neuropsychiatric and genetic aspects of a new hereditary disease characterized by progressive dementia and lipomembranous polycystic osteodysplasia.

1972 • 157 citations

Investigating regional white matter in schizophrenia using diffusion tensor imaging

2002 • 154 citations

Neuregulins increase alpha7 nicotinic acetylcholine receptors and enhance excitatory synaptic transmission in GABAergic interneurons of the hippocampus.

2001 • 151 citations

The GABAergic system in schizophrenia

2002 • 144 citations

Altered ratios of alternatively spliced long and short γ2 subunit mRNAs of the γ-amino butyrate type A receptor in prefrontal cortex of schizophrenics

1998 • 138 citations

Neuregulin Induces GABA_AReceptor Subunit Expression and Neurite Outgrowth in Cerebellar Granule Cells

1999 • 130 citations

The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia

2002 • 128 citations

Neuregulin Signaling Regulates Neural Precursor Growth and the Generation of OligodendrocytesIn Vitro

2001 • 121 citations

Neuregulins Increase α7 Nicotinic Acetylcholine Receptors and Enhance Excitatory Synaptic Transmission in GABAergic Interneurons of the Hippocampus

2001 • 114 citations

Pubertal neurodevelopment and the emergence of psychotic symptoms

2002 • 114 citations

Dysregulated brain development in adult men with schizophrenia: a magnetic resonance imaging study

2003 • 114 citations

Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders.

2002 • 108 citations

Differential Expression of ErbB3 and ErbB4 Neuregulin Receptors in Dopamine Neurons and Forebrain Areas of the Adult Rat

1999 • 104 citations

A role for the acetylcholine receptor-inducing protein ARIA in oligodendrocyte development.

1994 • 99 citations

L<scp>INKAGE</scp>A<scp>NALYSIS IN</scp>P<scp>SYCHIATRIC</scp>D<scp>ISORDERS</scp>: The Emerging Picture

2002 • 89 citations

Neuregulin1 downregulates postsynaptic GABA_a receptors at the hippocampal inhibitory synapse

2004 • 84 citations

Selective Alterations in Ionotropic Glutamate Receptors in the Anterior Cingulate Cortex in Schizophrenia

2002 • 75 citations

Neuregulin and erbB receptor expression in normal and diseased human white matter

1999 • 73 citations

Distribution of Microtubule-Associated Protein MAP2-Immunoreactive Interstitial Neurons in the Parahippocampal White Matter in Subjects With Schizophrenia

2002 • 64 citations

erbB3 is dispensable for oligodendrocyte development in vitro and in vivo

2003 • 39 citations