Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders.

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

2002 • 12,185 citations

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

2001 • 4,058 citations

Serial Analysis of Gene Expression

1995 • 3,659 citations

What are the functional consequences of neurocognitive deficits in schizophrenia?

1996 • 3,505 citations

Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

2000 • 3,126 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

Exploring the new world of the genome with DNA microarrays

1999 • 2,454 citations

Effect of COMT Val ^108/158 Met genotype on frontal lobe function and risk for schizophrenia

2001 • 2,408 citations

Antipsychotic-Induced Weight Gain: A Comprehensive Research Synthesis

1999 • 2,382 citations

High density synthetic oligonucleotide arrays

1999 • 2,256 citations

Use of a cDNA microarray to analyse gene expression patterns in human cancer

1996 • 2,002 citations

Expression profiling using cDNA microarrays

1999 • 1,689 citations

Parallel human genome analysis: microarray-based expression monitoring of 1000 genes.

1996 • 1,629 citations

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays

2000 • 1,356 citations

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

2001 • 1,194 citations

Genome-wide expression monitoring in Saccharomyces cerevisiae

1997 • 990 citations

Molecular Characterization of Schizophrenia Viewed by Microarray Analysis of Gene Expression in Prefrontal Cortex

2000 • 884 citations

Catching Up on Schizophrenia

2000 • 815 citations

Molecular interactions on microarrays

1999 • 788 citations

Discovery and analysis of inflammatory disease-related genes using cDNA microarrays

1997 • 740 citations

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

1996 • 729 citations

Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array

1999 • 725 citations

Gene expression profiles of laser-captured adjacent neuronal subtypes

1999 • 708 citations

The Effects of Risperidone on the Five Dimensions of Schizophrenia Derived by Factor Analysis

1997 • 705 citations

Making and reading microarrays

1999 • 681 citations

Assessment of the sensitivity and specificity of oligonucleotide (50mer) microarrays

2000 • 626 citations

The Regulator of G Protein Signaling Family

2000 • 586 citations

Drugs and the treatment of psychiatric disorders

1996 • 581 citations

Extensive polymorphisms observed in HIV–1 clade B protease gene using high–density oligonucleotide arrays

1996 • 545 citations

Location of a Major Susceptibility Locus for Familial Schizophrenia on Chromosome 1q21-q22

2000 • 528 citations

Schizophrenia

1994 • 489 citations

Postmortem brain abnormalities of the glutamate neurotransmitter system in autism

2001 • 489 citations

Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia

2001 • 448 citations

Epidemiology of schizophrenia: the global burden of disease and disability

2000 • 447 citations

Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain

1997 • 437 citations

Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

2002 • 428 citations

Novel antipsychotics and new onset diabetes

1998 • 416 citations

Clozapine, Olanzapine, Risperidone, and Haloperidol in the Treatment of Patients With Chronic Schizophrenia and Schizoaffective Disorder

2002 • 410 citations

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

2001 • 393 citations

Association and linkage analyses of RGS4 polymorphisms in schizophrenia

2002 • 374 citations

The GTPase-activating Protein RGS4 Stabilizes the Transition State for Nucleotide Hydrolysis

1996 • 354 citations

Sequencing of megabase plus DNA by hybridization: Theory of the method

1989 • 352 citations

The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: selective mRNA vulnerability and comparison with their encoded proteins

1995 • 349 citations

Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons

2000 • 310 citations

Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin.

1987 • 300 citations

Alterations in Chandelier Neuron Axon Terminals in the Prefrontal Cortex of Schizophrenic Subjects

1999 • 293 citations

Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx

2000 • 271 citations

Pre‐and Postmortem Influences on Brain RNA

1993 • 269 citations

Dopaminergic cell death induced by MPP⁺, oxidant and specific neurotoxicants shares the common molecular mechanism

2001 • 251 citations

Gene expression analysis in N‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R‐apomorphine

2001 • 250 citations

Application of cDNA microarrays to examine gene expression differences in schizophrenia

2001 • 250 citations

Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays

1999 • 245 citations

A Genetic Analysis of Neural Progenitor Differentiation

2001 • 241 citations

Gene Expression Profile for Schizophrenia

2002 • 239 citations

Olanzapine Increases Weight and Serum Triglyceride Levels

1999 • 231 citations

Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing.

1986 • 219 citations

Domains of psychopathology: an approach to the reduction of heterogeneity in schizophrenia.

1994 • 216 citations

Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene

1992 • 212 citations

Factors influencing relapse in the long-term course of schizophrenia

1997 • 210 citations

RGS proteins: more than just GAPs for heterotrimeric G proteins

1999 • 200 citations

Sensitivity Issues in DNA Array-Based Expression Measurements and Performance of Nylon Microarrays for Small Samples

1999 • 194 citations

Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein

2003 • 183 citations

Gene expression analysis in schizophrenia: Reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22

2002 • 182 citations

Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse.

1987 • 174 citations

The clinical implications of weight gain in schizophrenia.

2001 • 164 citations

Microarray analysis of gene expression in multiple sclerosis and EAE identifies 5-lipoxygenase as a component of inflammatory lesions

2001 • 151 citations

Gene expression profiling in the post-mortem human brain — no cause for dismay

2001 • 146 citations

Divergence of RGS proteins: evidence for the existence of six mammalian RGS subfamilies

1999 • 137 citations

AN ELECTRON MICROSCOPIC STUDY OF THE TYPES AND PROPORTIONS OF NEURONS IN THE CORTEX OF THE MOTOR AND VISUAL AREAS OF THE CAT AND RAT

1980 • 134 citations

TOGA: An automated parsing technology for analyzing expression of nearly all genes

2000 • 133 citations

Weight Gain

1999 • 126 citations

Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques

1999 • 123 citations

High-density cDNA filter analysis: a novel approach for large-scale, quantitative analysis of gene expression

1995 • 123 citations

Weight gain induced by clozapine

1995 • 117 citations

Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia

2001 • 113 citations

Up-Regulation of Calcineurin Aβ mRNA in the Alzheimer's Disease Brain: Assessment by cDNA Microarray

2001 • 110 citations

Altered expression of a-type but not b-type synapsin isoform in the brain of patients at high risk for Alzheimer's disease assessed by DNA microarray technique

2001 • 104 citations

A combined analysis of double‐blind studies with risperidone vs. placebo and other antipsychotic agents: factors associated with extrapyramidal symptoms

1999 • 98 citations

Pharmacotherapy of mental illness - a historical analysis

2001 • 96 citations

The Effects of Olanzapine on the 5 Dimensions of Schizophrenia Derived by Factor Analysis

2001 • 95 citations

Microarray Applications in Neuroscience

2001 • 93 citations

Klinefelter's syndrome as a model of anomalous cerebral laterality: Testing gene dosage in the X chromosome pseudoautosomal region using a DNA microarray

1998 • 91 citations

A comparison of microarray databases

2001 • 85 citations

Microarrays in brain research: the good, the bad and the ugly

2001 • 75 citations

Effects of risperidone on affective symptoms in patients with schizophrenia

2000 • 70 citations

cDNA microarray to study gene expression of dopaminergic neurodegeneration and neuroprotection in MPTP and 6-hydroxydopamine models: implications for idiopathic Parkinson’s disease

2000 • 69 citations

Selective Increases in Phosphoinositide Signaling Activity and G Protein Levels in Postmortem Brain from Subjects with Schizophrenia or Alcohol Dependence

1998 • 65 citations

Sharing gene expression data: an array of options

2001 • 58 citations

Drug Treatment of Schizophrenia in the 1990s

1997 • 58 citations

CYP2D6 Genotyping with Oligonucleotide Microarrays and Nortriptyline Concentrations in Geriatric Depression

2001 • 57 citations

Management strategies for the treatment of schizophrenia.

1999 • 52 citations

Ziprasidone, a New Atypical Antipsychotic Drug

2001 • 51 citations

Combining frequency and positional information to predict transcription factor binding sites

2001 • 50 citations

The “chip” as a specific genetic tool

2000 • 49 citations

Lithium-related genetics of bipolar disorder

2001 • 46 citations

Opposite changes in phosphoinositide-specific phospholipase C immunoreactivity in the left prefrontal and superior temporal cortex of patients with chronic schizophrenia

1999 • 44 citations

Effect of neuroleptic treatment on depressive symptoms in acute schizophrenic episodes

1997 • 42 citations

DNA microarrays in neuropsychopharmacology

2001 • 40 citations

Increase in [3H]cAMP binding sites and decrease in Giα and Goα immunoreactivities in left temporal cortices from patients with schizophrenia

1993 • 40 citations

Genes and subtypes of schizophrenia

2001 • 38 citations

Changes in protein kinase C and adenylate cyclase in the temporal lobe from subjects with schizophrenia

1997 • 38 citations

Long‐term treatment of mood disorders in schizophrenia

1995 • 37 citations

The sharing of cDNA microarray data

2001 • 37 citations

A Method for Analysis of Gene Expression Patterns

1994 • 37 citations

A relational schema for both array-based and SAGE gene expression experiments

2001 • 36 citations

Induction of cysteine string protein after chronic antidepressant treatment in rat frontal cortex

2001 • 35 citations

Efficacy and Safety of Risperidone in the Treatment of Schizoaffective Disorder

2001 • 34 citations

Microarrays: lost in a storm of data?

2001 • 32 citations

Cognitive Functioning in Schizophrenia

1996 • 31 citations

Assembly and use of a broadly applicable neural cDNA microarray.

2001 • 30 citations

Depressive symptoms in acute schizophrenic inpatients

1997 • 30 citations

Convergent functional genomics: application to bipolar disorder

2001 • 28 citations

Global „Burden of Disease”-Study for Psychiatric Disorders - Rationale and Application to the Cost-Effectiveness of Mental Health Care Interventions -

2001 • 21 citations

Radioactive 33-P probes in hybridization to glass cDNA microarrays using neural tissues

2001 • 20 citations

Treatment of the symptoms of schizophrenia: a combined analysis of double-blind studies comparing risperidone with haloperidol and other antipsychotic agents

2001 • 17 citations

Chips for Brains

2002 • 11 citations

DNA Arrays and Gene Expression Analysis in the Brain

2001 • 11 citations

Cell-mediated Side Effects of Psychopharmacological Treatment

2011 • 10 citations

DNA Microarrays and Human Brain Disorders

2001 • 7 citations

Microarrays in Brain Research: Data Quality and Limitations

2002 • 5 citations

Light-directed, programmable microarray synthesis

1999 • 2 citations