T-cell priming in bone marrow: the potential for long-lasting protective anti-tumor immunity

Immunobiology of Dendritic Cells

2000 • 6,653 citations

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

2001 • 5,893 citations

The Danger Model: A Renewed Sense of Self

2002 • 4,107 citations

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

1999 • 3,340 citations

Decoding the Patterns of Self and Nonself by the Innate Immune System

2002 • 2,096 citations

Effector and memory T-cell differentiation: implications for vaccine development

2002 • 1,757 citations

In Vivo Depletion of CD11c+ Dendritic Cells Abrogates Priming of CD8+ T Cells by Exogenous Cell-Associated Antigens

2002 • 1,734 citations

Cross-Presentation, Dendritic Cells, Tolerance and Immunity

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Maturation, Activation, and Protection of Dendritic Cells Induced by Double-stranded RNA

1999 • 727 citations

Dynamic Imaging of T Cell-Dendritic Cell Interactions in Lymph Nodes

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DEVELOPMENT AND MATURATION OF SECONDARY LYMPHOID TISSUES

1999 • 636 citations

A Role for CD40 Expression on CD8 ⁺ T Cells in the Generation of CD8 ⁺ T Cell Memory

2002 • 629 citations

Differing Activities of Homeostatic Chemokines CCL19, CCL21, and CXCL12 in Lymphocyte and Dendritic Cell Recruitment and Lymphoid Neogenesis

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Rescue of Newcastle Disease Virus from Cloned cDNA: Evidence that Cleavability of the Fusion Protein Is a Major Determinant for Virulence

1999 • 481 citations

The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics

2001 • 390 citations

Bone marrow as a priming site for T-cell responses to blood-borne antigen

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Measuring the diaspora for virus-specific CD8⁺T cells

2001 • 288 citations

Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways

2002 • 272 citations

Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow

2001 • 269 citations

Cell-Associated Ovalbumin Is Cross-Presented Much More Efficiently than Soluble Ovalbumin In Vivo

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Enrichment of memory T cells and other profound immunological changes in the bone marrow from untreated breast cancer patients

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Human tumor cell modification by virus infection: an efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle disease virus

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Newcastle disease virus-infected intact autologous tumor cell vaccine for adjuvant active specific immunotherapy of resected colorectal carcinoma.

1996 • 130 citations

Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide

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Human tumor cell infection by Newcastle Disease Virus leads to upregulation of HLA and cell adhesion molecules and to induction of interferons, chemokines and finally apoptosis

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TNF-Related Apoptosis-Inducing Ligand Mediates Tumoricidal Activity of Human Monocytes Stimulated by Newcastle Disease Virus

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Persistence of dormant tumor cells in the bone marrow of tumor cell-vaccinated mice correlates with long-term immunological protection.

1994 • 106 citations

Tumor-cell number and viability as quality and efficacy parameters of autologous virus-modified cancer vaccines in patients with breast or ovarian cancer.

1997 • 103 citations

EblacZ tumor dormancy in bone marrow and lymph nodes: active control of proliferating tumor cells by CD8+ immune T cells.

1998 • 102 citations

Molecular Cross-talk between the TRAIL and Interferon Signaling Pathways

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Immunization with virus-modified tumor cells.

1998 • 102 citations

Renal cell carcinoma treated by vaccines for active specific immunotherapy: Correlation of survival with skin testing by autologous tumor cells

1990 • 98 citations

Modification of tumor cells by a low dose of Newcastle disease virus

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Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination

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Dendritic cells pulsed with viral oncolysates potently stimulate autologous T cells from cancer patients

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An Atlas of the Blood and Bone Marrow

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T-cell immunity in the induction and maintenance of a tumour dormant state

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Dynamic Changes During the Immune Response in T Cell–Antigen-presenting Cell Clusters Isolated from Lymph Nodes

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Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development

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Newcastle disease virus infection induces B7-1/B7-2-independent T-cell costimulatory activity in human melanoma cells

2000 • 65 citations

Viral hemagglutinin augments peptide‐specific cytotoxic T cell responses

1993 • 62 citations

Scientific Interest in Newcastle Disease Virus Is Reviving

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Noncoding RNA danger motifs bridge innate and adaptive immunity and are potent adjuvants for vaccination

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Sialoadhesin-Positive Host Macrophages Play an Essential Role in Graft-Versus-Leukemia Reactivity in Mice

1999 • 51 citations

Efficient engraftment of human primary breast cancer transplants in nonconditioned NOD/Scid mice

2003 • 50 citations

Generation of dendritic cells from human bone marrow mononuclear cells: Advantages for clinical application in comparison to peripheral blood monocyte derived cells

2002 • 48 citations

Two ways to induce innate immune responses in human PBMCs: Paracrine stimulation of IFN-α responses by viral protein or dsRNA

2003 • 46 citations

PACT, a Double-Stranded RNA Binding Protein Acts as a Positive Regulator for Type I Interferon Gene Induced by Newcastle Disease Virus

2001 • 45 citations

Intra-pinna anti-tumor vaccination with self-replicating infectious RNA or with DNA encoding a model tumor antigen and a cytokine

2000 • 44 citations

Cognate interactions between memory T cells and tumor antigen‐presenting dendritic cells from bone marrow of breast cancer patients: Bidirectional cell stimulation, survival and antitumor activity in vivo

2002 • 43 citations

TUMOR RESPONSE AND 4 YEAR SURVIVAL-DATA OF PATIENTS WITH ADVANCED RENAL-CELL CARCINOMA TREATED WITH AUTOLOGOUS TUMOR VACCINE AND SUBCUTANEOUS R-IL-2 AND IFN-ALPHA(2B)

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EFFECTIVE IMMUNE REJECTION OF ADVANCED METASTASIZED CANCER

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An exact comparison between the efficiency of two‐ and three‐cell‐type clusters in mediating helper activity

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T cell memory, anergy and immunotherapy in breast cancer.

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Replication-Competent, Oncolytic Newcastle Disease Virus for Cancer Therapy

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Conditioning of the secondary cytotoxic T-lymphocyte response to YC8 tumor

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Graft-versus-leukemia reactivity involves cluster formation between superantigen-reactive donor T lymphocytes and host macrophages.

1998 • 22 citations

Production and Selection of b Lymphocytes in Bone Marrow: Lymphostromal Interactions and Apoptosis in Normal, Mutant and Transgenic Mice

1994 • 20 citations

Functional and in situ evidence for nitric oxide production driven by CD40-CD40L interactions in graft-versus-leukemia reactivity.

2000 • 17 citations

Therapy of human tumors in NOD/SCID mice with patient derived re-activated memory T cells from bone marrow

2001 • 15 citations

Breaking tolerance to a tumor-associated viral superantigen as a basis for graft-versus-leukemia reactivity

2000 • 13 citations

A novel tumour model system for the study of long-term protective immunity and immune T cell memory

2003 • 12 citations

Improvements of Survival in Nine Phase II Clinical Studies with Different Types of Cancer Upon Anti- Tumor Vaccination with an Autologous Tumor Cell Vaccine Modified by Virus Infection to Introduce Danger Signals

2003 • 4 citations