A novel tumour model system for the study of long-term protective immunity and immune T cell memory

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

Effector and memory T-cell differentiation: implications for vaccine development

2002 • 1,757 citations

The Central Role of CD4+ T Cells in the Antitumor Immune Response

1998 • 1,332 citations

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

2001 • 1,277 citations

Response of naïve and memory CD8+ T cells to antigen stimulation in vivo

2000 • 542 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow

2001 • 269 citations

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.

1996 • 259 citations

Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection

1999 • 206 citations

CD8+ Memory T Cells (CD44high, Ly-6C+) Are More Sensitive than Naive Cells (CD44low, Ly-6C−) to TCR/CD8 Signaling in Response to Antigen

1998 • 177 citations

Cutting Edge: CD4+ T Cell Control of CD8+ T Cell Reactivity to a Model Tumor Antigen

2000 • 168 citations

Tumor metastases and cell‐mediated immunity in a model system in DBA/2 mice. I. Tumor invasiveness in vitro and metastasis formation in vivo

1979 • 159 citations

Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I MHC-restricted CTL epitopes.

1993 • 154 citations

CD4+ T Cells in Adoptive Immunotherapy and the Indirect Mechanism of Tumor Rejection

2000 • 119 citations

Alkali hydrolysis of recombinant proteins allows for the rapid identification of class I MHC-restricted CTL epitopes.

1993 • 118 citations

Tumor metastases and cell‐mediated immunity in a model system in DBA/2 mice.: Iv. Antigenic differences between a metastasizing variant and the parental tumor line revealed by cytotoxic T lymphocytes

1979 • 115 citations

Irradiation induced expression of CD31, ICAM-1 and VCAM-1 in human microvascular endothelial cells.

2000 • 95 citations

Scattered micrometastases visualized at the single‐cell level: Detection and re‐isolation of lacZ‐labeled metastasized lymphoma cells

1994 • 68 citations

Premature TCRαβ Expression and Signaling in Early Thymocytes Impair Thymocyte Expansion and Partially Block Their Development

2001 • 62 citations

Irradiation enhances the support of haemopoietic cell transmigration, proliferation and differentiation by endothelial cells

2001 • 61 citations

Expression and Functional Significance of Adhesion Molecules on Cultured Endothelial Cells in Response to Ionizing Radiation

2001 • 60 citations

Tumor metastases and cell‐mediated immunity in a model system in DBA/2 mice. VI. Similar specificity patterns of protective anti‐tumor immunity in vivo and of cytolytic T cells in vitro

1979 • 58 citations

CD4⁺ helper T cells are required for resistance to a highly metastatic murine tumor

1987 • 53 citations

Sialoadhesin-Positive Host Macrophages Play an Essential Role in Graft-Versus-Leukemia Reactivity in Mice

1999 • 51 citations

A Low Affinity TCR Ligand Restores Positive Selection of CD8+ T Cells In Vivo

2001 • 42 citations

Pattern and load of spontaneous liver metastasis dependent on host immune status studied with a lacZ transduced lymphoma

1994 • 37 citations

Tumour‐Specific CTL response requiring interactions of four different cell types and recognition of MHC class I and class II restricted tumour antigens

1993 • 31 citations

Recruitment and activation of tumor-specific immune T cells in situ. CD8+ cells predominate the secondary response in sponge matrices and exert both delayed-type hypersensitivity-like and cytotoxic T lymphocyte activity.

1989 • 28 citations

Ionizing radiation alters hepatic cholesterol metabolism and plasma lipoproteins in Syrian hamster

1999 • 27 citations

Suicide induced by cytolytic activity controls the differentiation of memory CD8+ T lymphocytes

2001 • 27 citations

In situ activation of syngeneic tumour-specific cytotoxic T lymphocytes: Intra-pinna immunization followed by restimulation in the peritoneal cavity

1991 • 19 citations

Superiority of the ear pinna over a subcutaneous tumour inoculation site for induction of a Th1-type cytokine response

1998 • 13 citations

GAMMA-IRRADIATION SUPPRESSES T-CELL MEDIATED PROTECTIVE IMMUNITY AGAINST A METASTATIC TUMOR IN THE AFFERENT PHASE OF THE IMMUNE-RESPONSE BUT ENHANCES IT IN THE EFFERENT PHASE WHEN GIVEN BEFORE IMMUNE CELL TRANSFER

1994 • 11 citations

ADOPTIVE TRANSFER OF PROTECTIVE IMMUNITY AGAINST A HIGH METASTATIC TUMOR-CELL VARIANT BY SMALL NUMBERS OF TUMOR-SPECIFIC IN-SITU ACTIVATED PERITONEAL EFFECTOR T-CELLS

1994 • 3 citations

AUGMENTATION OF PROTECTIVE IMMUNOTHERAPY AGAINST METASTATIC ESB LYMPHOMA-CELLS BY COMBINING IMMUNE CELL TRANSFER WITH HOST IRRADIATION, ANTIGEN RESTIMULATION AND/OR ANTI-TNF-ALPHA ANTIBODY TREATMENT

1995 • 2 citations

Getting TCR transgenics to work on time

2001 • 2 citations