Replication-Competent, Oncolytic Newcastle Disease Virus for Cancer Therapy

Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus

1976 • 651 citations

Rescue of Newcastle Disease Virus from Cloned cDNA: Evidence that Cleavability of the Fusion Protein Is a Major Determinant for Virulence

1999 • 481 citations

Complete nucleotide sequence of Newcastle disease virus: evidence for the existence of a new genus within the subfamily Paramyxovirinae.

1999 • 329 citations

Newcastle Disease in Free-Living and Pet Birds

1988 • 300 citations

Newcastle disease virus selectively kills human tumor cells

1992 • 235 citations

Newcastle disease virus as an antineoplastic agent

1965 • 214 citations

Activation of precursors to both glycoproteins of Newcastle disease virus by proteolytic cleavage

1977 • 207 citations

Recovery of Infectious SV5 from Cloned DNA and Expression of a Foreign Gene

1997 • 195 citations

Newcastle disease virus evolution

1989 • 176 citations

A phase II study on the postsurgical management of stage II malignant melanoma with a Newcastle disease virus oncolysate

1983 • 171 citations

Circulating Interferon in Mice after Intravenous Injection of Virus

1963 • 164 citations

Newcastle disease virus evolution

1989 • 162 citations

Nucleotide sequences of the trailer, nucleocapsid protein gene and intergenic regions of Newcastle disease virus strain Beaudette C and completion of the entire genome sequence.

1998 • 155 citations

Complete regression of human fibrosarcoma xenografts after local Newcastle disease virus therapy.

1994 • 150 citations

Identification of vaccine strains of Newcastle disease virus.

1955 • 144 citations

Newcastle Disease Virus as an Antineoplastic Agent: Induction of Tumor Necrosis Factor- and Augmentation of Its Cytotoxicity2

1988 • 143 citations

Paramyxovirus replication and pathogenesis. Reverse genetics transforms understanding

1999 • 141 citations

A hitherto unrecorded disease of fowls due to a filter-passing virus.

1927 • 134 citations

Newcastle disease virus-infected intact autologous tumor cell vaccine for adjuvant active specific immunotherapy of resected colorectal carcinoma.

1996 • 130 citations

Complete Regression of Human Neuroblastoma Xenografts in Athymic Mice After Local Newcastle Disease Virus Therapy

1994 • 122 citations

Observations on the Repeated Administration of Viruses to a Patient with Acute Leukemia

1964 • 113 citations

A ten-year follow-up on stage II Malignant Melanoma patients treated postsurgically with newcastle disease virus oncolysate

1992 • 113 citations

Attenuated veterinary virus vaccine for the treatment of cancer.

1993 • 111 citations

A 15-Year Follow-up of AJCC Stage III Malignant Melanoma Patients Treated Postsurgically with Newcastle Disease Virus (NDV) Oncolysate and Determination of Alterations in the CD8 T Cell Repertoire

1998 • 109 citations

Active specific immunotherapy with Newcastle-diseasevirus-modified autologous tumor cells following resection of liver metastases in colorectal cancer

1992 • 107 citations

Immunization with virus-modified tumor cells.

1998 • 102 citations

Recovery of infectious respiratory syncytial virus expressing an additional, foreign gene

1996 • 91 citations

Beneficial treatment of patients with advanced cancer using a Newcastle disease virus vaccine (MTH-68/H).

1999 • 88 citations

Newcastle Disease Virus

1965 • 85 citations

Accommodation of foreign genes into the Sendai virus genome: sizes of inserted genes and viral replication

1999 • 82 citations

Characterization and expression of a murine gene homologous to human EPA/TIMP: a virus-induced gene in the mouse.

1987 • 79 citations

Nucleotide sequence of the 5′-terminus of Newcastle disease virus and assembly of the complete genomic sequence: agreement with the “rule of six”

1998 • 76 citations

An Outbreak of Conjunctivitis Due to Newcastle Disease Virus (NDV) Occurring in Poultry Workers

1952 • 75 citations

Reverse genetics of negative-strand RNA viruses: Closing the circle

1999 • 74 citations

The Matrix Protein of Newcastle Disease Virus Localizes to the Nucleus via a Bipartite Nuclear Localization Signal

1993 • 73 citations

The carboxyterminus of the hemagglutinin-neuraminidase of Newcastle disease virus is exposed at the surface of the viral envelope

1984 • 72 citations

Exogenous Interferon and Inducers of Interferon in the Treatment of Balb/c Mice inoculated with RC19 Tumour Cells

1969 • 69 citations

VIRUSES IN THE TREATMENT OF CANCER

1971 • 65 citations

Viral hemagglutinin augments peptide‐specific cytotoxic T cell responses

1993 • 62 citations

Induction of Cytokines and Cytotoxicity against Tumor Cells by Newcastle Disease Virus

1994 • 58 citations

Scientific Interest in Newcastle Disease Virus Is Reviving

1999 • 58 citations

Neurochemical and neuroendocrine responses to Newcastle disease virus administration in mice

1994 • 58 citations

Control by Vaccination

1988 • 52 citations

Induction of NO synthesis in macrophages by Newcastle disease virus is associated with activation of nuclear factor-κB

1996 • 52 citations

Genetics and Paragenetic Phenomena of Paramyxoviruses

1977 • 39 citations

Biological and Molecular Characterization of Newcastle Disease Virus Isolates from Surveillance of Live Bird Markets in the Northeastern United States

1997 • 39 citations

Introduction of adhesive and costimulatory immune functions into tumor cells by infection with Newcastle Disease Virus.

1998 • 39 citations

Regulatory Mechanisms of Murantes and CRG-2 Chemokine Gene Induction in Central Nervous System Glial Cells by Virus

1995 • 37 citations

Early Induction of Proinflammatory Cytokine and Type I Interferon mRNAs Following Newcastle Disease Virus, Poly [rI:rC], or Low-Dose LPS Challenge of the Mouse

1997 • 36 citations

Virus potentiation of tumor vaccine T-cell stimulatory capacity requires cell surface binding but not infection.

1997 • 34 citations

Apoptosis as a cause of death in chicken embryos inoculated with Newcastle disease virus

1995 • 31 citations

Analysis of the Interferons Induced in MiceIn Vivoand in MacrophagesIn Vitroby Newcastle Disease Virus and by Polyinosinic-Polycytidylic Acid

1986 • 30 citations

The Genetics of Paramyxoviruses

1991 • 27 citations

Newcastle Disease Virus-induced Plasma Membrane Damage

1974 • 26 citations

Tumor immunity after viral oncolysis

1966 • 25 citations

Newcastle Disease Virus Replication

1988 • 24 citations

Characterization of Newcastle disease virus vaccines by biological properties and sequence analysis of the hemagglutinin-neuraminidase protein gene

1996 • 24 citations

CLINICAL STUDIES EMPLOYING INTERFERON INDUCERS IN MAN AND ANIMALS *

1970 • 23 citations

Apoptosis in chicken embryo fibroblasts caused by Newcastle disease virus

1995 • 20 citations

Correlation of proteolytic cleavage of F protein precursors in paramyxoviruses with expression of the fur, PACE4 and PC6 genes in mammalian cells

1994 • 20 citations

Reactions of Human Sera to Avian Adenoviruses and Newcastle Disease Virus

1971 • 18 citations

Newcastle disease virus antibodies in human sera.

1981 • 17 citations

Role of Interferon in the Anti-Melanoma Effects of Poly (I).Poly (C) and Newcastle Disease Virus

1973 • 16 citations

Quality Control of Vaccines

1988 • 15 citations

Retinoic acid enhances killing of neuroblastoma cells by Newcastle disease virus

1993 • 15 citations

Laboratory Experiments with Living Newcastle Disease Vaccine

1949 • 10 citations

Newcastle Disease Virus: Virus Particle and RNA Synthesis in Different Host Cells and at Different Temperatures

1974 • 8 citations