Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis

MicroRNAs

2004 • 33,206 citations

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

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The functions of animal microRNAs

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R: A Language for Data Analysis and Graphics

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DAVID: Database for Annotation, Visualization, and Integrated Discovery

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

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MicroRNA signatures in human cancers

2006 • 7,358 citations

Oncomirs — microRNAs with a role in cancer

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MicroRNAs: small RNAs with a big role in gene regulation

2004 • 6,733 citations

Surfing the p53 network

2000 • 6,487 citations

The nuclear RNase III Drosha initiates microRNA processing

2003 • 4,966 citations

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

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R: A Language for Data Analysis and Graphics

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MicroRNA genes are transcribed by RNA polymerase II

2004 • 4,200 citations

Silencing of microRNAs in vivo with ‘antagomirs’

2005 • 3,846 citations

The Versatile Role of microRNA-30a in Human Cancer

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Non-coding RNAs and cancer: microRNAs and beyond

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Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

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MicroRNA biogenesis: coordinated cropping and dicing

2005 • 2,443 citations

c-Myc-regulated microRNAs modulate E2F1 expression

2005 • 2,371 citations

Identification of Mammalian microRNA Host Genes and Transcription Units

2004 • 1,966 citations

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

2004 • 1,827 citations

Control of apoptosis by p53

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A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors

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p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

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A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

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Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

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Processing of intronic microRNAs

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MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells

2007 • 800 citations

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

2005 • 790 citations

On Differential Variability of Expression Ratios: Improving Statistical Inference about Gene Expression Changes from Microarray Data

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A custom microarray platform for analysis of microRNA gene expression

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Myogenic factors that regulate expression of muscle-specific microRNAs

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A Hexanucleotide Element Directs MicroRNA Nuclear Import

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The Analysis of Gene Expression Data: Methods and Software

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The inhibitors of apoptosis: there is more to life than Bcl2

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MicroRNAs as oncogenes

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On parametric empirical Bayes methods for comparing multiple groups using replicated gene expression profiles

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An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

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CHD5 Is a Tumor Suppressor at Human 1p36

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The p53 tumor suppressor participates in multiple cell cycle checkpoints

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Immortal Human Pancreatic Duct Epithelial Cell Lines with Near Normal Genotype and Phenotype

2000 • 314 citations

Tumor-suppressor p53: implications for tumor development and prognosis.

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The Bcl-2-regulated apoptotic pathway

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Differentially Regulated Micro-RNAs and Actively Translated Messenger RNA Transcripts by Tumor Suppressor p53 in Colon Cancer

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Death and decoy receptors and p53-mediated apoptosis

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Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors

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Immortalization with telomerase of the Nestin-positive cells of the human pancreas

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Consistent association of 1p loss of heterozygosity with pheochromocytomas from patients with multiple endocrine neoplasia type 2 syndromes.

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Two distinct regions involved in 1p deletion in human primary breast cancer.

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Identifying Allelic Loss and Homozygous Deletions in Pancreatic Cancer without Matched Normals Using High-Density Single-Nucleotide Polymorphism Arrays

2006 • 87 citations

Chromosome Band 1p36 Contains a Putative Tumor Suppressor Gene Important in the Evolution of Chronic Myelocytic Leukemia

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Parametric Empirical Bayes Methods for Microarrays

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Microsatellite analysis at 1p36.3 in malignant melanoma of the skin

2003 • 37 citations

Deleted Work

1955 • 0 citations