The functions of animal microRNAs

MicroRNAs

2004 • 33,206 citations

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Prediction of Mammalian MicroRNA Targets

2003 • 5,070 citations

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

2000 • 4,834 citations

Identification of Novel Genes Coding for Small Expressed RNAs

2001 • 4,834 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1993 • 4,021 citations

MicroRNAs Modulate Hematopoietic Lineage Differentiation

2003 • 3,241 citations

Identification of Tissue-Specific MicroRNAs from Mouse

2002 • 3,236 citations

MicroRNA targets in Drosophila

2003 • 3,228 citations

An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans

2001 • 3,225 citations

An Extensive Class of Small RNAs in Caenorhabditis elegans

2001 • 2,806 citations

Prediction of Plant MicroRNA Targets

2002 • 2,239 citations

A microRNA in a Multiple-Turnover RNAi Enzyme Complex

2002 • 2,052 citations

bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila

2003 • 2,012 citations

A uniform system for microRNA annotation

2003 • 1,841 citations

MicroRNA-Directed Cleavage of HOXB8 mRNA

2004 • 1,680 citations

Specificity of microRNA target selection in translational repression

2004 • 1,631 citations

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs

2004 • 1,406 citations

siRNAs can function as miRNAs

2003 • 1,252 citations

The microRNAs ofCaenorhabditis elegans

2003 • 1,232 citations

Vertebrate MicroRNA Genes

2003 • 1,190 citations

The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation

1999 • 1,174 citations

Embryonic Stem Cell-Specific MicroRNAs

2003 • 1,126 citations

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

2003 • 1,003 citations

A biochemical framework for RNA silencing in plants

2003 • 985 citations

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

2003 • 915 citations

New microRNAs from mouse and human

2003 • 881 citations

The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA

1997 • 844 citations

Both Natural and Designed Micro RNAs Can Inhibit the Expression of Cognate mRNAs When Expressed in Human Cells

2002 • 824 citations

Identification of Drosophila MicroRNA Targets

2003 • 792 citations

A combined computational-experimental approach predicts human microRNA targets

2004 • 776 citations

The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor

2000 • 761 citations

A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

2003 • 756 citations

Computational identification of DrosophilamicroRNA genes

2003 • 724 citations

MicroRNAs and Other Tiny Endogenous RNAs in C. elegans

2003 • 702 citations

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

2004 • 623 citations

Sequence-Specific Inhibition of Small RNA Function

2004 • 577 citations

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR

2004 • 441 citations

Two Genetic Circuits Repress the Caenorhabditis elegans Heterochronic Gene lin-28 after Translation Initiation

2002 • 397 citations

The Caenorhabditis elegans hunchback-like Gene lin-57/hbl-1 Controls Developmental Time and Is Regulated by MicroRNAs

2003 • 370 citations

The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target

2003 • 354 citations

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode

2004 • 345 citations

Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene

2003 • 335 citations

Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites

2003 • 325 citations

Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and Broad-Complex gene activity

2003 • 316 citations

Computational identification of microRNA targets

2004 • 308 citations

Computational and Experimental Identification of C. elegans microRNAs

2003 • 288 citations

The bantam Gene Regulates Drosophila Growth

2002 • 186 citations

A transcriptional regulatory cascade that controls left/right asymmetry in chemosensory neurons ofC. elegans

2003 • 180 citations

The Timing oflin-4RNA Accumulation Controls the Timing of Postembryonic Developmental Events inCaenorhabditis elegans

1999 • 148 citations

Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis

2003 • 126 citations