The invariant chain inhibits presentation of endogenous antigens by a human fibroblast cell line

Two populations of Ia-like molecules on a human B cell line.

1980 • 1,112 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

1990 • 565 citations

Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.

1986 • 513 citations

Immunology: The ins and outs of antigen processing and presentations

1986 • 498 citations

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

1990 • 486 citations

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1991 • 394 citations

Pathogenesis of Burkitt lymphoma: Expression of an activated c-myc oncogene causes the tumorigenic conversion of EBV-infected human B lymphoblasts

1987 • 302 citations

Class II MHC molecules can use the endogenous pathway of antigen presentation

1990 • 271 citations

MHC class II—Restricted presentation of intracellular antigen

1991 • 260 citations

Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization.

1993 • 221 citations

HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells

1989 • 201 citations

Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells

1992 • 201 citations

Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes.

1992 • 189 citations

Human T cell response to the surface antigen of hepatitis B virus (HBsAg). Endosomal and nonendosomal processing pathways are accessible to both endogenous and exogenous antigen.

1988 • 180 citations

Expression of H-2Dd and H-2Ld mouse major histocompatibility antigen genes in L cells after DNA-mediated gene transfer.

1983 • 144 citations

Human major histocompatibility complex class II invariant chain is expressed on the cell surface.

1990 • 138 citations

Two forms of the la antigen-associated invariant chain result from alternative initiations at two in-phase AUGs

1986 • 124 citations

A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3).

1984 • 119 citations

Diversity of Endogenous Epitopes Bound to MHC Class II Molecules Limited by Invariant Chain

1994 • 116 citations

Cytotoxic T cell recognition of an endogenous class I HLA peptide presented by a class II HLA molecule.

1990 • 109 citations

A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex.

1991 • 106 citations

Class II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme.

1991 • 89 citations

Human T cells cannot act as autonomous antigen-presenting cells, but induce tolerance in antigen-specific and alloreactive responder cells.

1992 • 74 citations

Analysis of HLA-DR glycoproteins by DNA-mediated gene transfer. Definition of DR2 beta gene products and antigen presentation to T cell clones from leprosy patients.

1988 • 66 citations

Structure and biosynthesis of the signal‐sequence receptor

1990 • 66 citations

Major histocompatibility complex class II-restricted presentation of an internally synthesized antigen displays cell-type variability and segregates from the exogenous class II and endogenous class I presentation pathways.

1993 • 65 citations

Exogenous peptides compete for the presentation of endogenous antigens to major histocompatibility complex class II-restricted T cells.

1991 • 60 citations

Biological and biochemical characterization of an SV40-transformed xeroderma pigmentosum cell line

1984 • 49 citations

Structural and functional studies of HLA-DR restricted antigen recognition by human helper T lymphocyte clones by using transfected murine cell lines.

1988 • 39 citations

Human T cell recognition of influenza A nucleoprotein. Specificity and genetic restriction of immunodominant T helper cell epitopes.

1991 • 35 citations

Fine mapping of HLA class II monoclonal antibody specificities using transfected L cells

1990 • 26 citations

Generation and characterization of an HLA-DR?-specific monoclonal antibody using L-cell transfectants expressing human and mouse class II major histocompatibility dimers

1991 • 7 citations