A gene required for class II-restricted antigen presentation maps to the major histocompatibility complex.

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Report of the committee on the genetic constitution of the X chromosome (Part 1 of 3)

1990 • 597 citations

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids

1985 • 580 citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1990 • 468 citations

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

1988 • 447 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

The Minimal Number of Class II MHC-Antigen Complexes Needed for T Cell Activation

1990 • 410 citations

Presentation of viral antigen controlled by a gene in the major histocompatibility complex

1990 • 381 citations

Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

1981 • 374 citations

Complete sequence of an HLA-dR beta chain deduced from a cDNA clone and identification of multiple non-allelic DR beta chain genes.

1983 • 271 citations

Recognition of HLA-B27 and related antigen by a monoclonal antibody

1982 • 240 citations

Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2

1978 • 239 citations

Defective processing and presentation of exogenous antigens in mutants with normal HLA class II genes

1990 • 236 citations

The binary logic of antigen processing and presentation to T cells

1990 • 235 citations

ETHYL METHANESULFONATE-INDUCED REVERSION OF BACTERIOPHAGE T4rII MUTANTS

1963 • 202 citations

Mutations that impair a posttranscriptional step in expression of HLA-A and -B antigens.

1985 • 183 citations

Autologous Peptides Constitutively Occupy the Antigen Binding Site on Ia

1988 • 157 citations

Production of β₂‐Microglobulin by Normal and Malignant Human Cell Lines and Peripheral Lymphocytes

1974 • 120 citations

Genetic mapping of a human class II antigen beta-chain cDNA clone to the SB region of the HLA complex.

1983 • 110 citations

Stable variants affecting B cell alloantigens in human lymphoid cells

1978 • 109 citations

HLA-DQ molecules form alpha-beta heterodimers of mixed allotype.

1988 • 94 citations

The LMP antigens: A stable MHC-controlled multisubunit protein complex

1986 • 93 citations

Molecular organization of the HLA-SB region of the human major histocompatibility complex and evidence for two SB beta-chain genes.

1984 • 91 citations

Direct demonstration of an HLA-DR allotypic determinant on the low molecular weight (beta) subunit using a mouse monoclonal antibody specific for DR3

1982 • 83 citations

H–2-linked low-molecular weight polypeptide antigens assemble into an unusual macromolecular complex

1984 • 80 citations

Polymorphism and complexity of the human DC and murine I-A alpha chain genes.

1983 • 68 citations

Gene dosage and gene expression in the HLA region: Evidence from deletion variants

1982 • 66 citations

Isolation of a cDNA clone for the human HLA-DR antigen alpha chain by using a synthetic oligonucleotide as a hybridization probe.

1982 • 63 citations

Processing of tetanus toxin by human antigen-presenting cells. Evidence for donor and epitope-specific processing pathways.

1989 • 62 citations

HLA class II regulation and structure. Analysis with HLA-DR3 and HLA-DP point mutants.

1985 • 60 citations

Report of the committee on the genetic constitution of chromosome 6

1982 • 57 citations

Isolation and Characterization of Human B Cell Alloantigens

1976 • 52 citations

Importance of HLA-DQ and -DP restriction elements in T-cell responses to soluble antigens: Mutational analysis

1987 • 39 citations

Deletion mapping of HLA and chromosome 6p genes.

1985 • 35 citations

Structural relationship of the SB β-chain gene to HLA-D-region genes and murine I-region genes

1984 • 29 citations