Synergistic effect betweenIL-10 andbcl-2 genotypes in determining susceptibility to systemic lupus erythematosus

The 1982 revised criteria for the classification of systemic lupus erythematosus

1982 • 14,553 citations

The Fas Death Factor

1995 • 4,070 citations

Interleukin-10

1993 • 1,820 citations

AN INVESTIGATION OF POLYMORPHISM IN THE INTERLEUKIN‐10 GENE PROMOTER

1997 • 1,730 citations

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

1995 • 1,549 citations

Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease.

1991 • 876 citations

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

1996 • 794 citations

Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice.

1994 • 543 citations

Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus.

1995 • 542 citations

CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population.

1995 • 426 citations

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

1997 • 408 citations

Mapping of the human IL10 gene and further characterization of the 5' flanking sequence

1997 • 389 citations

Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein.

1994 • 344 citations

CTLA4 mediates antigen-specific apoptosis of human T cells.

1995 • 331 citations

Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus.

1997 • 279 citations

The role of IL-10 in human B cell activation, proliferation, and differentiation.

1995 • 241 citations

Autoimmune disease. a problem of defective apoptosis

1994 • 224 citations

Tetranucleotide repeat polymorphism at the human c-fes/fps proto-oncogene (FES)

1991 • 219 citations

Bcl-2: a repressor of lymphocyte death

1992 • 217 citations

Association between polymorphisms at the human IL‐10 locus and systemic lupus erythematosus

1997 • 176 citations

IL-10 inhibits apoptotic cell death in human T cells starved of IL-2

1993 • 123 citations

High levels of bcl‐2 protein in circulating t lymphocytes, but not b lymphocytes, of patients with systemic lupus erythematosus

1994 • 103 citations

Interleukin-10 inhibits apoptotic cell death in infectious mononucleosis T cells.

1994 • 76 citations

Genetics of autoimmune disease

1995 • 55 citations

The bc1-2 Proto-Oncogene is Overexpressed in Systemic Lupus Erythematosus

1994 • 45 citations

Bcl-2 and Fas, Molecules Which Influence Apoptosis. A Possible Role in Systemic Lupus Erythematosus?

1994 • 37 citations

Susceptibility loci for lupus: a guiding light from murine models?

1997 • 22 citations