The T cell as a bridge between innate and adaptive immune systems: Implications for the kidney

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Chemokines

2000 • 3,773 citations

Cellular and Molecular Immunology

1994 • 3,469 citations

Cellular and Molecular Immunology

1992 • 2,768 citations

Phylogenetic Perspectives in Innate Immunity

1999 • 2,478 citations

Innate Immunity

2000 • 1,715 citations

NK CELL RECEPTORS

1998 • 1,666 citations

T-Cell Function and Migration — Two Sides of the Same Coin

2000 • 1,437 citations

Acute Renal Failure

1996 • 1,377 citations

Sequence and specificity of two antibacterial proteins involved in insect immunity

1981 • 1,358 citations

High Survival Rates of Kidney Transplants from Spousal and Living Unrelated Donors

1995 • 1,216 citations

Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis

1990 • 989 citations

Natural and synthetic non-peptide antigens recognized by human γδ T cells

1995 • 974 citations

A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway

1996 • 822 citations

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1998 • 785 citations

An innate sense of danger

1998 • 752 citations

Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury.

1996 • 723 citations

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

1995 • 672 citations

MIF regulates innate immune responses through modulation of Toll-like receptor 4

2001 • 573 citations

A NEW ANALYSIS OF ALLOGENEIC INTERACTIONS

1975 • 551 citations

CDR3 length in antigen-specific immune receptors.

1994 • 503 citations

Antibody to intercellular adhesion molecule 1 protects the kidney against ischemic injury.

1994 • 495 citations

Involvement of Toll-Like Receptor 4 in Innate Immunity to Respiratory Syncytial Virus

2001 • 492 citations

Activation of Dual T Cell Signaling Pathways by the Chemokine RANTES

1995 • 463 citations

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1994 • 462 citations

Impaired IL-18 processing protects caspase-1–deficient mice from ischemic acute renal failure

2001 • 460 citations

The Morphology of “Acute Tubular Necrosis” in Man

1979 • 452 citations

Immunologic ‘ignorance’ of vascularized organ transplants in the absence of secondary lymphoid tissue

2000 • 446 citations

Predominant role for C5b-9 in renal ischemia/reperfusion injury

2000 • 443 citations

Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure

2001 • 419 citations

The nature of major histocompatibility complex recognition by γδ T cells

1994 • 407 citations

Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure

2001 • 381 citations

Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury

2000 • 368 citations

CD4(+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver.

1997 • 365 citations

Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice

2000 • 344 citations

Chronic renal allograft rejection: Immunologic and nonimmunologic risk factors

1996 • 325 citations

The biology of Stat4 and Stat6

2000 • 310 citations

VDJ recombination

1992 • 307 citations

Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway

1999 • 305 citations

The collectins in innate immunity

1996 • 302 citations

Leukocytes, cell adhesion molecules and ischemic acute renal failure

1997 • 281 citations

Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats.

1997 • 280 citations

ISCHEMIC ACUTE TUBULAR NECROSIS INDUCES AN EXTENSIVE LOCAL CYTOKINE RESPONSE

1995 • 271 citations

The serum mannose-binding protein and the macrophage mannose receptor are pattern recognition molecules that link innate and adaptive immunity

1998 • 246 citations

Endotoxin, Toll-like receptor 4, and the afferent limb of innate immunity

2000 • 238 citations

The role of the B7 costimulatory pathway in experimental cold ischemia/reperfusion injury.

1997 • 228 citations

Postischemic renal injury is mediated by neutrophils and leukotrienes

1989 • 211 citations

Mycophenolate mofetil prevents the progressive renal failure induced by 5/6 renal ablation in rats

1999 • 203 citations

Acute T-Cell Activation Is Detectable in Unstable Angina

1997 • 190 citations

Role of immunocompetent cells in nonimmune renal diseases

2001 • 187 citations

Mycophenolate mofetil attenuates renal injury in the rat remnant kidney

1998 • 181 citations

S-Allyl Cysteine Inhibits Activation of Nuclear Factor Kappa B in Human T Cells

1997 • 170 citations

Antisense oligonucleotides for ICAM-1 attenuate reperfusion injury and renal failure in the rat

1996 • 155 citations

Role of CD11a and CD11b in ischemic acute renal failure in rats

1994 • 150 citations

PROMINENT AND SUSTAINED UP-REGULATION OF GP130-SIGNALING CYTOKINES AND OF THE CHEMOKINE MIP-2 IN MURINE RENAL ISCHEMIA-REPERFUSION INJURY1

2000 • 150 citations

Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans

1997 • 147 citations

An evaluation of the neutrophil as a mediator of in vivo renal ischemic-reperfusion injury.

1989 • 145 citations

Antibodies to ICAM-1 Protect Kidneys in Severe Ischemic Reperfusion Injury

1995 • 145 citations

An innate view of γδ T cells

1997 • 142 citations

Involvement of Lipopolysaccharide Binding Protein, CD14, and Toll-Like Receptors in the Initiation of Innate Immune Responses byTreponemaGlycolipids

2000 • 141 citations

Hypothesis: Is renal allograft rejection initiated by the response to injury sustained during the transplant process?

1999 • 141 citations

A RANDOMIZED MULTICENTER TRIAL COMPARING LEUKOCYTE FUNCTION-ASSOCIATED ANTIGEN-1 MONOCLONAL ANTIBODY WITH RABBIT ANTITHYMOCYTE GLOBULIN AS INDUCTION TREATMENT IN FIRST KIDNEY TRANSPLANTATIONS

1996 • 141 citations

Combining an Antiproteinuric Approach with Mycophenolate Mofetil Fully Suppresses Progressive Nephropathy of Experimental Animals

1999 • 140 citations

Anti-B7-1 blocks mononuclear cell adherence in vasa recta after ischemia

2001 • 137 citations

Cytotoxic T Lymphocytes Are Activated Following Myocardial Infarction and Can Recognize and Kill Healthy Myocytes In Vitro

2000 • 134 citations

Mild renal ischemia activates primed neutrophils to cause acute renal failure

1992 • 122 citations

Expression of cytokine-like genes JE and KC is increased during renal ischemia

1991 • 120 citations

Control of natural killer cell-mediated innate resistance against the intracellular pathogen Listeria monocytogenes by gamma/delta T lymphocytes

1996 • 111 citations

Cold liver ischemia-reperfusion injury critically depends on liver T cells and is improved by donor pretreatment with interleukin 10 in mice

2000 • 109 citations

CD28-B7 blockade in organ dysfunction secondary to cold ischemia/reperfusion injury: Rapid Communication

1997 • 106 citations

The role of the leukocyte adhesion molecules VLA-4, LFA-1, and Mac-1 in allergic airway responses in the rat.

1994 • 104 citations

Small molecule selectin ligand inhibition improves outcome in ischemic acute renal failure

2001 • 103 citations

Effect of neutrophil depletion on ischemic renal injury in the rat.

1989 • 102 citations

Enhanced protection from renal ischemia: Reperfusion injury with A2A-adenosine receptor activation and PDE 4 inhibition

2001 • 101 citations

FK506 prevents stroke-induced generation of ceramide and apoptosis signaling

1999 • 98 citations

THE EFFECT OF MYCOPHENOLATE MOFETIL AND POLYPHENOLIC BIOFLAVONOIDS ON RENAL ISCHEMIA REPERFUSION INJURY AND REPAIR

2000 • 86 citations

Transplant surgery injury recruits recipient MHC class II-positive leukocytes into the kidney

1999 • 82 citations

THE PROTECTIVE EFFECT OF FK506 PRETREATMENT AGAINST RENAL ISCHEMIA/REPERFUSION INJURY IN RATS1

1992 • 77 citations

Complement activation in heart diseases

2000 • 73 citations

Effect of in vitro generation of oxygen free radicals on T cell function in young and old rats

1998 • 65 citations

Therapeutic Regulation of the Complement System in Acute Injury States

1994 • 64 citations

α-Melanocyte-stimulating hormone inhibits renal injury in the absence of neutrophils

1998 • 54 citations

T‐Lymphocytes Contribute to Hepatic Leukostasis and Hypoxic Stress Induced by Gut Ischemia‐Reperfusion

1999 • 52 citations

Lymphocytes mediate TNF-alpha-induced endothelial cell adhesion molecule expression: studies on SCID and RAG-1 mutant mice.

1997 • 48 citations

Early cellular events in the lung allograft

1992 • 46 citations

Cytokine and Adhesion Molecule Expression in SCID Mice Reconstituted with CD4+ T Cells

2000 • 44 citations

Beneficial Effects of Cyclosporine and Rapamycin in Small Bowel Ischemic Injury

1996 • 43 citations

DONOR TREATMENT WITH MYCOPHENOLATE MOFETIL

2000 • 42 citations

Delayed graft function: immediate and late impact

1997 • 26 citations

Postanoxic T Lymphocyte–Endothelial Cell Interactions Induce Tumor Necrosis Factor-α Production and Neutrophil Adhesion

2000 • 22 citations

Effect of Pretreatment with FTY720 and Cyclosporin on Ischaemia-Reperfusion Injury of the Liver in Rats

1999 • 22 citations

ANTITHROMBIN III TREATMENT IMPROVES PARAMETERS OF ACUTE INFLAMMATION IN A HIGHLY HISTOINCOMPATIBLE MODEL OF RAT LUNG ALLOGRAFT REJECTION

1999 • 20 citations

Heparin attenuated neutrophil infiltration but did not affect renal injury induced by ischemia reperfusion

1997 • 16 citations

FK506 reduces oxidative hepatic injury following cold ischemic preservation and transplantation.

1996 • 16 citations

Interleukin-1 treatment increases neutrophils but not antioxidant enzyme activity or resistance to ischemia-reperfusion injury in rat kidneys

1994 • 14 citations

IMMUNE FUNCTION

2000 • 13 citations

The Role of Inflammatory Mediators in the Mechanism of the Host Immune Response Induced by Ischemia-Reperfusion Injury

2000 • 9 citations

The Role of Inflammatory Mediators in the Mechanism of the Host Immune Response Induced by Ischemia-Reperfusion Injury

2000 • 7 citations