Serotonin transporter binding sites and mRNA levels in depressed persons committing suicide

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2004 • 1,494 citations

Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behavior

1983 • 1,290 citations

Neurotransmitter Transporters: Recent Progress

1993 • 1,089 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

Cytoarchitecture of the Human Brain Stem.

1955 • 922 citations

Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter

1994 • 904 citations

The Human Hippocampus

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San Diego Suicide Study

1986 • 504 citations

Tritiated Imipramine Binding Sites Are Decreased in the Frontal Cortex of Suicides

1982 • 478 citations

Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization- receptor autoradiographic analysis

1990 • 466 citations

Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims

1995 • 461 citations

Zur Serotonin-Hypothese der Depression*

1990 • 397 citations

Cytoarchitecture of the Human Brain Stem

1983 • 302 citations

Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia and depression, and suicides

1984 • 301 citations

An Evaluation of the Family History Method for Ascertaining Psychiatric Disorders

1982 • 300 citations

Neurotransmitter and neuromodulatory mechanisms involved in alcohol abuse and alcoholism

1995 • 269 citations

Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine.

1987 • 264 citations

Decreased Imipramine Binding in the Brains of Patients with Depressive Illness

1983 • 253 citations

High‐affinity binding of [¹²⁵I]RTI‐55 to dopamine and serotonin transporters in rat brain

1992 • 211 citations

Regional brain expression of serotonin transporter mRNA and its regulation by reuptake inhibiting antidepressants

1993 • 210 citations

Human brain receptor alterations in suicide victims

1982 • 179 citations

High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims.

1994 • 172 citations

Serotonergic mechanisms in brains of suicide victims

1986 • 153 citations

Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self- administration

1994 • 146 citations

Cocaine use increases [3HWIN 35428 binding sites in human striatum

1993 • 129 citations

Autoradiographic Analysis of Tritiated Imipramine Binding in the Human Brain Post Mortem: Effects of Suicide

1989 • 114 citations

Is platelet imipramine binding reduced in depression? A meta-analysis

1994 • 102 citations

Brain 5-HT uptake sites, labelled with [3H]paroxetine, in antidepressant-free depressed suicides

1990 • 85 citations

Antidepressive drugs can change the affinity of [3H]imipramine and [3H]paroxetine binding to platelet and neuronal membranes

1985 • 84 citations

Allosteric Interaction Between the Site Labeled by [³H]Imipramine and the Serotonin Transporter in Human Platelets

1987 • 84 citations

Expression of Serotonin Transporter Messenger RNA in the Human Brain

1994 • 83 citations

McN-5652: a highly potent inhibitor of serotonin uptake.

1988 • 77 citations

Postmortem Neurochemical Studies in Depression

1986 • 72 citations

3H-imipramine binding in the frontal cortex of suicides

1989 • 70 citations

Platelets 3H 5-HT uptake in descendants from alcoholic patients: A potential risk factor for alcohol dependence?

1993 • 68 citations

Binding of the cocaine analog 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane to serotonin and dopamine transporters: different ionic requirements for substrate and 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane binding.

1993 • 66 citations

Serotonin transporter mRNA in rat brain is regulated by classical antidepressants

1994 • 64 citations

Methyl 3β‐(4‐[¹²⁵I]Iodophenyl)Tropane‐2β‐Carboxylate In Vitro Binding to Dopamine and Serotonin Transporters Under “Physiological” Conditions

1994 • 60 citations

[¹²⁵I]RTI‐55 Binding to Cocaine‐Sensitive Dopaminergic and Serotonergic Uptake Sites in the Human Brain

1993 • 58 citations

Autoradiographic characterization of [3H]imipramine and [3H]citalopram binding in rat and human brain: species differences and relationships to serotonin innervation patterns

1992 • 56 citations

Platelet serotonin uptake in men with family histories of alcoholism.

1991 • 55 citations

The Preparation of Biologically Active Messenger RNA from Human Postmortem Brain Tissue

1981 • 47 citations

Temperature Dependence of Drug Interaction with the Platelet 5‐Hydroxytryptamine Transporter: A Clue to the Imipramine Selectivity Paradox

1987 • 45 citations

Stability of messenger RNA in postmortem human brains and construction of human brain cDNA libraries

1990 • 43 citations

A common binding site for tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors at the substrate recognition site of the neuronal sodium-dependent 5-hydroxytryptamine transporter

1989 • 42 citations

Characterization and localization of [125I]RTI-121 binding sites in human striatum and medial temporal lobe.

1995 • 41 citations

Binding of the cocaine analog 2 beta-[3H] carboxymethoxy-3 beta-(4-fluorophenyl)tropane to the serotonin transporter.

1991 • 41 citations

Reversed hemispheric asymmetry of imipramine binding in suicide victims

1991 • 37 citations

The use ofin situ hybridization histochemistry for the study of neuropeptide gene expression in the human brain

1990 • 30 citations

Symmetrical hemispheric distribution of 3H-Paroxetine binding sites in postmortem human brain from controls and suicides

1990 • 28 citations

Drug inhibition indicates a single-site model of the 5-HT uptake site/antidepressant binding site in rat and human brain

1989 • 21 citations

Unaltered number of brain serotonin uptake sites in suicide victims

1992 • 18 citations

Thermodynamics of the interactions of tricyclic drugs with binding sites for [3H]imipramine in mouse cerebral cortex

1984 • 18 citations