Postmortem Neurochemical Studies in Depression

The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects

1968 • 4,041 citations

5-HIAA in the Cerebrospinal Fluid

1976 • 1,430 citations

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol.

1979 • 1,321 citations

A Hundred Cases of Suicide: Clinical Aspects

1974 • 1,289 citations

The Biochemistry of Affective Disorders

1967 • 1,183 citations

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

1982 • 1,049 citations

Biogenic Amines and Emotion

1967 • 878 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain

1984 • 701 citations

Receptor Sensitivity and the Mechanism of Action of Antidepressant Treatment

1981 • 645 citations

Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease.

1985 • 570 citations

INCREASED SEROTONIN-2 BINDING SITES IN FRONTAL CORTEX OF SUICIDE VICTIMS

1983 • 527 citations

Tritiated Imipramine Binding Sites Are Decreased in the Frontal Cortex of Suicides

1982 • 478 citations

5-Hydroxytryptamine in the Hind-Brain of Depressive Suicides

1967 • 424 citations

DEPRESSION BY RESERPINE OF THE NORADRENALINE CONCENTRATION IN THE HYPOTHALAMUS OF THE CAT

1956 • 424 citations

Mental Depression in Hypertensive Patients Treated for Long Periods with Large Doses of Reserpine

1954 • 306 citations

NORADRENALINE, 5-HYDROXYTRYPTAMINE, AND 5-HYDROXYINDOLEACETIC ACID IN HINDBRAINS OF SUICIDAL PATIENTS

1968 • 304 citations

Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia and depression, and suicides

1984 • 301 citations

Effect of Reserpine on the Storage of Catechol Amines in Brain and Other Tissues

1961 • 300 citations

CSF monoamine metabolites in melancholia

1984 • 286 citations

5-HYDROXYTRYPTAMINE, NORADRENALINE, AND DOPAMINE IN BRAINSTEM, HYPOTHALAMUS, AND CAUDATE NUCLEUS OF CONTROLS AND OF PATIENTS COMMITTING SUICIDE BY COAL-GAS POISONING

1969 • 259 citations

Decreased Imipramine Binding in the Brains of Patients with Depressive Illness

1983 • 253 citations

Serotonin as a mediator of reserpine action in brain.

1956 • 230 citations

Neuroendocrine tests of monoamine function in man: a review of basic theory and its application to the study of depressive illness

1980 • 227 citations

DETERMINATION OF MONOAMINE AND MONOAMINE METABOLITES IN THE HUMAN BRAIN: POST MORTEM STUDIES IN A GROUP OF SUICIDES AND IN A CONTROL GROUP

1976 • 224 citations

Serotonin Receptor Changes in Dementia of the Alzheimer Type

1984 • 194 citations

Simultaneous quantification of dopamine, 5-hydroxytryptaine and four metabolically related compounds by means of reversed-phase high-performance liquid chromatography with electrochemical detection

1981 • 190 citations

Human brain receptor alterations in suicide victims

1982 • 179 citations

5-Hydroxyindoles in Human Cerebrospinal Fluids

1960 • 162 citations

Localisation of Tricyclic Antidepressant Binding Sites on Serotonin Nerve Terminals

1981 • 151 citations

Monoamine metabolism in senile dementia of Alzheimer type

1983 • 148 citations

High affinity binding of [3H]paroxetine and [3H]imipramine to human platelet membranes

1983 • 145 citations

Neuropeptides in Alzheimer's disease, depression and schizophrenia

1981 • 119 citations

Biogenic amine metabolites in cerebrospinal fluid of patients with affective disorders

1978 • 100 citations

Regional serotonin levels in brain: a comparison of depressive suicides and alcoholic suicides with controls.

1976 • 99 citations

Biochemistry of Dementia

1981 • 79 citations

[3H]RX 781094: A new antagonist ligand labels α2-adrenoceptors in the rat brain cortex

1983 • 64 citations

Post mortem levels of thyrotropin-releasing hormone and neurotensin in the amygdala in Alzheimer's disease, schizophrenia and depression

1983 • 60 citations

MODIFIED AMINE HYPOTHESIS FOR THE ÆTIOLOGY OF AFFECTIVE ILLNESS

1972 • 55 citations

Regional distribution of norepinephrine and dopamine in brains of depressive suicides and alcoholic suicides.

1975 • 48 citations

Adrenergic receptors in frontal cortex in human brain

1985 • 33 citations

Cholinergic Receptor Binding in the Frontal Cortex of Suicide Victims

1986 • 26 citations

Cholinergic receptor binding in the frontal cortex of suicide victims

1984 • 17 citations

Amitriptyline in man: Decreased formation of central 5‐hydroxyindoleacetic acid

1974 • 16 citations

4‐HYDROXY‐3‐METHOXYPHENYLGLYCOL AS AN INDEX OF BRAIN NORADRENALINE TURNOVER IN ENDOGENOUS DEPRESSION

1980 • 14 citations