Hedgehog acts directly on the zebrafish dermomyotome to promote myogenic differentiation

Stages of embryonic development of the zebrafish

1995 • 11,263 citations

Hedgehog signaling in animal development: paradigms and principles

2001 • 2,919 citations

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

2002 • 1,442 citations

A Pax3/Pax7-dependent population of skeletal muscle progenitor cells

2005 • 1,076 citations

Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.

1982 • 932 citations

The formation of skeletal muscle: from somite to limb

2003 • 859 citations

Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

1998 • 838 citations

The Hedgehog Response Network: Sensors, Switches, and Routers

2004 • 821 citations

Redefining the Genetic Hierarchies Controlling Skeletal Myogenesis: Pax-3 and Myf-5 Act Upstream of MyoD

1997 • 815 citations

Early stages of chick somite development

1995 • 781 citations

Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos

1996 • 653 citations

Identification of separate slow and fast muscle precursor cells in vivo, prior to somite formation

1996 • 652 citations

Mutations affecting somite formation and patterning in the zebrafish, Danio rerio

1996 • 513 citations

A Somitic Compartment of Tendon Progenitors

2003 • 507 citations

Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite.

1995 • 504 citations

Regulation of Pax-3 expression in the dermomyotome and its role in muscle development

1994 • 491 citations

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

2002 • 484 citations

Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites

1994 • 451 citations

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development

1995 • 424 citations

Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification

1994 • 372 citations

A Hedgehog-Insensitive Form of Patched Provides Evidence for Direct Long-Range Morphogen Activity of Sonic Hedgehog in the Neural Tube

2001 • 364 citations

Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog

1997 • 356 citations

The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity

2000 • 297 citations

The Whereabouts of a Morphogen: Direct Evidence for Short- and Graded Long-Range Activity of Hedgehog Signaling Peptides

2001 • 288 citations

Zebrafishsmoothenedfunctions in ventral neural tube specification and axon tract formation

2001 • 287 citations

Somite development in zebrafish

2000 • 285 citations

Sonic hedgehog controls epaxial muscle determination through Myf5 activation

1999 • 269 citations

Cellular Mechanisms of Post-Embryonic Muscle Growth in Aquaculture Species

2001 • 268 citations

Multiple Muscle Cell Identities Induced by Distinct Levels and Timing of Hedgehog Activity in the Zebrafish Embryo

2003 • 265 citations

Arteries and veins: making a difference with zebrafish

2002 • 263 citations

Genetic analysis of zebrafishgli1andgli2reveals divergent requirements forgligenes in vertebrate development

2003 • 239 citations

Sequential activation of three myogenic regulatory genes during somite morphogenesis in quail embryos

1992 • 210 citations

Mechanisms of ventral patterning in the vertebrate nervous system

2006 • 210 citations

A Two-Step Mechanism for Myotome Formation in Chick

2004 • 209 citations

Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification

2002 • 202 citations

Location and growth of epaxial myotome precursor cells

1997 • 198 citations

Positive and Negative Regulation of Muscle Cell Identity by Members of the hedgehog and TGF-β Gene Families

1997 • 196 citations

Control of somite patterning by Sonic hedgehog and its downstream signal response genes

1998 • 183 citations

Sonic Hedgehog induces proliferation of committed skeletal muscle cells in the chick limb

1998 • 179 citations

The Sonic hedgehog pathway independently controls the patterning,proliferation and survival of neuroepithelial cells by regulating Gli activity

2006 • 176 citations

Distributions of PAX6 and PAX7 proteins suggest their involvement in both early and late phases of chick brain development

1997 • 176 citations

Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region

2006 • 173 citations

Development of the lateral musculature in the teleost, Brachydanio rerio: A fine structural study

1969 • 168 citations

A molecular mechanism enabling continuous embryonic muscle growth – a balance between proliferation and differentiation

1999 • 161 citations

Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites

2000 • 155 citations

The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo

2001 • 153 citations

Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation

2004 • 149 citations

Specific pan-neural crest expression of zebrafishCrestin throughout embryonic development

2001 • 140 citations

Generality of vertebrate developmental patterns: evidence for a dermomyotome in fish

2006 • 132 citations

Fgf8 drives myogenic progression of a novel lateral fast muscle fibre population in zebrafish

2005 • 127 citations

The zebrafish Pax3 and Pax7 homologues are highly conserved, encode multiple isoforms and show dynamic segment-like expression in the developing brain

1998 • 126 citations

Distinct mechanisms regulate slow-muscle development

2001 • 124 citations

Sonic hedgehog is a survival factor for hypaxial muscles during mouse development

2001 • 121 citations

The origin and fate of pioneer myotomal cells in the avian embryo

1998 • 117 citations

The cellular mechanism by which the dermomyotome contributes to the second wave of myotome development

1998 • 117 citations

Zebrafish Slow Muscle Cell Migration Induces a Wave of Fast Muscle Morphogenesis

2004 • 103 citations

Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling

2004 • 101 citations

Pax3 and Pax7 expression and regulation in the avian embryo

2006 • 100 citations

Characterisation of a SecondpatchedGene in the ZebrafishDanio rerioand the Differential Response ofpatchedGenes to Hedgehog Signalling

1999 • 98 citations

In Vivo Regulation of Somite Differentiation and Proliferation by Sonic Hedgehog

1999 • 95 citations

Cadherin-Mediated Differential Cell Adhesion Controls Slow Muscle Cell Migration in the Developing Zebrafish Myotome

2003 • 92 citations

Analysis of a key regulatory region upstream of theMyf5gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus

2003 • 90 citations

Hedgehog signaling is required for commitment but not initial induction of slow muscle precursors

2004 • 83 citations

Hedgehog regulation of superficial slow muscle fibres inXenopusand the evolution of tetrapod trunk myogenesis

2004 • 75 citations

Myotome formation: a multistage process

1999 • 74 citations

Stem cells to tissue: molecular, cellular and anatomical heterogeneity in skeletal muscle

2003 • 72 citations

3 Sclerotome Induction and Differentiation

1999 • 70 citations

Origin of the epaxial and hypaxial myotome in avian embryos

2000 • 68 citations

Cell lineages generating axial muscle in the zebrafish embryo

1987 • 67 citations

The development of muscle fiber type identity in zebrafish cranial muscles

2005 • 65 citations

9 Determination and Morphogenesis in Myogenic Progenitor Cells: An Experimental Embryological Approach

1999 • 62 citations

Sonic hedgehog enhances somite cell viability and formation of primary slow muscle fibers in avian segmented mesoderm

1999 • 58 citations

Identification of early postmitotic cells in distinct embryonic sites and their possible roles in morphogenesis

1998 • 55 citations

Differential effects of N-cadherin-mediated adhesion on the development of myotomal waves

2006 • 53 citations

Muscle development and growth.

2001 • 53 citations

Gli function is essential for motor neuron induction in zebrafish

2005 • 51 citations

Tissue In Situ Hybridization: Methods in Animal Development

1997 • 48 citations

Hedgehog can drive terminal differentiation of amniote slow skeletal muscle

2004 • 41 citations

Expression of the growth cone specific epitope CDA 1 and the Synaptic vesicle protein SVP38 in the developing mammalian cerebral cortex

1989 • 40 citations

Sonic Hedgehog Inhibits the Terminal Differentiation of Limb Myoblasts Committed to the Slow Muscle Lineage

2002 • 39 citations

Skeletal muscle fibre type specification during embryonic development.

2002 • 31 citations