Multiple Muscle Cell Identities Induced by Distinct Levels and Timing of Hedgehog Activity in the Zebrafish Embryo

Hedgehog signaling in animal development: paradigms and principles

2001 • 2,919 citations

Effective targeted gene ‘knockdown’ in zebrafish

2000 • 2,464 citations

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

2002 • 1,442 citations

Expression of engrailed proteins in arthropods, annelids, and chordates

1989 • 1,019 citations

Developmental regulation of zebrafish MyoD in wild-type, no tail and spadetail embryos

1996 • 653 citations

Identification of separate slow and fast muscle precursor cells in vivo, prior to somite formation

1996 • 652 citations

Myogenic Regulatory Factors and the Specification of Muscle Progenitors in Vertebrate Embryos

2002 • 566 citations

Patterning activities of vertebrate hedgehog proteins in the developing eye and brain

1995 • 557 citations

Sonic Hedgehog-induced Activation of the Gli1Promoter Is Mediated by GLI3

1999 • 528 citations

Mutations affecting somite formation and patterning in the zebrafish, Danio rerio

1996 • 513 citations

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

1995 • 491 citations

Mammalian Suppressor-of-Fused modulates nuclear–cytoplasmic shuttling of GLI-1

1999 • 454 citations

High-Frequency Generation of Transgenic Zebrafish Which Reliably Express GFP in Whole Muscles or the Whole Body by Using Promoters of Zebrafish Origin

1997 • 426 citations

Patterning of the Zebrafish Retina by a Wave of Sonic Hedgehog Activity

2000 • 373 citations

Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog

1997 • 356 citations

Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish

1998 • 355 citations

Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo.

1996 • 351 citations

Use of Real-Time Quantitative PCR to Validate the Results of cDNA Array and Differential Display PCR Technologies

2001 • 328 citations

Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube.

1997 • 323 citations

Induction of a specific muscle cell type by a hedgehog-like protein in zebrafish

1996 • 320 citations

Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning

1996 • 299 citations

The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity

2000 • 297 citations

Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning

1999 • 292 citations

Zebrafishsmoothenedfunctions in ventral neural tube specification and axon tract formation

2001 • 287 citations

Analysis of the zebrafishsmoothenedmutant reveals conserved and divergent functions of hedgehog activity

2001 • 266 citations

Gli proteins and Hedgehog signaling: development and cancer

1999 • 249 citations

Genetic analysis of zebrafishgli1andgli2reveals divergent requirements forgligenes in vertebrate development

2003 • 239 citations

Diversity of expression of engrailed-like antigens in zebrafish

1991 • 211 citations

Mouse Suppressor of fused is a negative regulator of Sonic hedgehog signaling and alters the subcellular distribution of Gli1

1999 • 203 citations

Suppressor of Fused opposes Hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus

2000 • 197 citations

Positive and Negative Regulation of Muscle Cell Identity by Members of the hedgehog and TGF-β Gene Families

1997 • 196 citations

Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation

2001 • 191 citations

Regionalization within the mammalian telencephalon is mediated by changes in responsiveness to Sonic Hedgehog

1998 • 177 citations

Suppressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway

1998 • 155 citations

The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo

2001 • 153 citations

Hedgehog Signalling Is Required for Maintenance of myf5 and myoD Expression and Timely Terminal Differentiation in Zebrafish Adaxial Myogenesis

2001 • 144 citations

Gli regulation by the opposing activities of Fused and Suppressor of Fused

2000 • 137 citations

Control of Muscle Cell-Type Specification in the Zebrafish Embryo by Hedgehog Signalling

1999 • 136 citations

Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster.

1992 • 130 citations

Vertebrate Homologs of Drosophila Suppressor of Fused Interact with the Gli Family of Transcriptional Regulators

1999 • 127 citations

Distinct mechanisms regulate slow-muscle development

2001 • 124 citations

Restricted expression of the homeobox gene prox 1 in developing zebrafish

1998 • 114 citations

Characterisation of a SecondpatchedGene in the ZebrafishDanio rerioand the Differential Response ofpatchedGenes to Hedgehog Signalling

1999 • 98 citations

Epaxial-adaxial-hypaxial regionalisation of the vertebrate somite: evidence for a somitic organiser and a mirror-image duplication

2001 • 51 citations