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Different Responses of Epidermal and Hair Follicular Cells to Radiation Correlate with Distinct Patterns of p53 and p21 Induction

Data up to Jan 2025

Published1999
Citations69
References35

Total Citations Per Year

Abstract

References (35)

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1995 • 4,043 citations

Radiobiology for the Radiologist.

1974 • 3,582 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

Tumor spectrum analysis in p53-mutant mice

1994 • 2,034 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

Radiation-induced cell cycle arrest compromised by p21 deficiency

1995 • 1,249 citations

Suppression of ICE and Apoptosis in Mammary Epithelial Cells by Extracellular Matrix

1995 • 1,184 citations

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.

1995 • 1,114 citations

Radiobiology for the Radiologist

1988 • 807 citations

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells.

1996 • 738 citations

Genetic determinants of p53-induced apoptosis and growth arrest.

1996 • 472 citations

Analysis of apoptosis during hair follicle regression (catagen)

1997 • 353 citations

Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle.

1996 • 333 citations

The Skin: Its Structure and Response to Ionizing Radiation

1990 • 330 citations

p21Waf1/Cip1 protects against p53-mediated apoptosis of human melanoma cells

1997 • 305 citations

Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene

1996 • 264 citations

Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo

1995 • 240 citations

The p53 response to ionising radiation in adult and developing murine tissues.

1996 • 206 citations

Loss of p 21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm -deficient mice

1997 • 169 citations

Repair Defect in p21 WAF1/CIP1 -/- human cancer cells.

1996 • 158 citations

Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard

1997 • 153 citations

Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways

1998 • 117 citations

Changes in Radiosensitivity and Dispersion of Chromatin during the Cell Cycle of Synchronous Chinese Hamster Cells

1972 • 112 citations

Anti-apoptotic activity of low levels of wild-type p53.

1996 • 109 citations

Radiation-Induced p53 and p21WAF–1/CIP1 Expression in the Murine Intestinal Epithelium

1998 • 101 citations

p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein.

1995 • 95 citations

DNA Damage Responses: p53 Induction, Cell Cycle Perturbations, and Apoptosis

1994 • 84 citations

Handbook of radiobiology

1995 • 83 citations

The molecular basis for radiation effects on cells.

1966 • 80 citations

Expression of P53, P21/WAF/CIP, BCL-2, BAX, BCL-X, and BAK In Radiation-Induced Apoptosis in Testicular Germ Cell Tumor Lines

1998 • 41 citations

Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpesvirus thymidine kinase occurs by p53-independent apoptosis.

1996 • 40 citations

Induction of p53‐independent Apoptosis Associated with G2M Arrest Following DNA Damage in Human Colon Cancer Cell Lines

1997 • 40 citations

Some Principles of Radiobiology: A Selective Review

1981 • 10 citations

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Different Responses of Epidermal and Hair Follicular Cells to Radiation Correlate with… (1999) – American Journal Of Pathology | Metascience Observatory Explorer