Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis

Mitochondrial Diseases in Man and Mouse

1999 • 3,008 citations

Reactive Oxygen Species and the Central Nervous System

1992 • 2,931 citations

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

2002 • 2,422 citations

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1991 • 2,240 citations

Production of Reactive Oxygen Species by Mitochondria

2003 • 1,519 citations

Analysis of Molecular Masses and Oligomeric States of Protein Complexes by Blue Native Electrophoresis and Isolation of Membrane Protein Complexes by Two-Dimensional Native Electrophoresis

1994 • 1,211 citations

A role for uncoupling protein‐2 as a regulator of mitochondrial hydrogen peroxide generation

1997 • 756 citations

Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1

2001 • 700 citations

Mitochondrial Electron Transport Complex I Is a Potential Source of Oxygen Free Radicals in the Failing Myocardium

1999 • 690 citations

Invited Review: Contractile activity-induced mitochondrial biogenesis in skeletal muscle

2001 • 682 citations

Energy Metabolism in Uncoupling Protein 3 Gene Knockout Mice

2000 • 679 citations

Regulation of Mitochondrial Biogenesis in Skeletal Muscle by CaMK

2002 • 659 citations

Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1

2001 • 642 citations

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.

1995 • 599 citations

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

2002 • 582 citations

Neuronal Activity-Dependent Cell Survival Mediated by Transcription Factor MEF2

1999 • 510 citations

MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type

2000 • 455 citations

TRANSCRIPTION OF THE MAMMALIAN MITOCHONDRIAL GENOME

1984 • 442 citations

Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.

2000 • 423 citations

Role of oxidative stress in transition of hypertrophy to heart failure

1996 • 422 citations

Regulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and mitochondrial function by MEF2 and HDAC5

2003 • 409 citations

Superoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side

2002 • 386 citations

Tissue Expression and Immunolocalization of Tumor Necrosis Factor-α in Postinfarction Dysfunctional Myocardium

1999 • 359 citations

Prognostic importance of atrial natriuretic peptide in patients with chronic heart failure

1989 • 354 citations

Rapid Reactive Oxygen Species Production by Mitochondria in Endothelial Cells Exposed to Tumor Necrosis Factor- α Is Mediated by Ceramide

2001 • 341 citations

Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells

2002 • 339 citations

Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade.

1996 • 293 citations

Nuclear control of respiratory chain expression in mammalian cells.

1997 • 265 citations

Regulation of PGC-1 Promoter Activity by Protein Kinase B and the Forkhead Transcription Factor FKHR

2003 • 260 citations

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

1999 • 244 citations

Chapter 13 Blue-native gels to isolate protein complexes from mitochondria

2001 • 231 citations

A Human Mitochondrial Transcription Factor Is Related to RNA Adenine Methyltransferases and Binds S-Adenosylmethionine

2002 • 202 citations

Lipopolysaccharide Stimulates Mitochondrial Biogenesis via Activation of Nuclear Respiratory Factor-1

2003 • 185 citations

Changing pattern of organ dysfunction in early human sepsis is related to mortality

2000 • 182 citations

Electrical stimulation of neonatal cardiomyocytes results in the sequential activation of nuclear genes governing mitochondrial proliferation and differentiation

1997 • 166 citations

Selected Contribution: Effects of contractile activity on mitochondrial transcription factor A expression in skeletal muscle

2001 • 161 citations

Postlipopolysaccharide Oxidative Damage of Mitochondrial DNA

2003 • 153 citations

Reactive Oxygen Species Produced by Liver Mitochondria of Rats in Sepsis

1995 • 145 citations

Mechanism for Peroxisome Proliferator-activated Receptor-α Activator-induced Up-regulation of UCP2 mRNA in Rodent Hepatocytes

2002 • 129 citations

Nuclear respiratory factor 1 activation sites in genes encoding the gamma-subunit of ATP synthase, eukaryotic initiation factor 2 alpha, and tyrosine aminotransferase. Specific interaction of purified NRF-1 with multiple target genes.

1992 • 126 citations

Redox Regulation of cAMP-responsive Element-binding Protein and Induction of Manganous Superoxide Dismutase in Nerve Growth Factor-dependent Cell Survival

2003 • 124 citations

Reactive Oxygen Species and the Central Nervous System

1992 • 116 citations

Oxidant-Mediated Activation of Mitogen- Activated Protein Kinases and Nuclear Transcription Factors in the Cardiovascular System

1998 • 108 citations

In the rat, tumor necrosis factor α administration results in an increase in both UCP2 and UCP3 mRNAs in skeletal muscle: a possible mechanism for cytokine‐induced thermogenesis?

1998 • 97 citations

Up-Regulation of Uncoupling Protein 3 Gene Expression by Fatty Acids and Agonists for PPARs in L6 Myotubes

2001 • 92 citations

Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism

2001 • 86 citations

Mitochondrial DNA alterations as a source of human disorders

1993 • 86 citations

Concentration dependence of the dielectric constant in mixed oxides MxOyMp′Oq

2001 • 78 citations

The role of thyroid hormone and promoter diversity in the regulation of nuclear encoded mitochondrial proteins

1995 • 70 citations

Rapid mtDNA deletion by oxidants in rat liver mitochondria after hemin exposure

2002 • 62 citations

Role of Oxidative Stress in Transition of Hypertrophy to Heart Failure

1996 • 54 citations

Transcription of the Mammalian Mitochondrial Genome

1984 • 37 citations

Reversal of Hypocalcemia and Decreased Afterload in Sepsis

1998 • 33 citations

Up-Regulation of Uncoupling Protein 3 Gene Expression by Fatty Acids and Agonists for PPARs in L6 Myotubes

2001 • 23 citations

Deleted Work

1955 • 0 citations