Mitochondrial Electron Transport Complex I Is a Potential Source of Oxygen Free Radicals in the Failing Myocardium

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Protein Oxidation and Aging

1992 • 2,687 citations

Mitochondrial Complex I Deficiency in Parkinson's Disease

1990 • 2,147 citations

MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE

1989 • 1,717 citations

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1980 • 1,609 citations

Apoptosis in Myocytes in End-Stage Heart Failure

1996 • 1,446 citations

Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide

1994 • 1,214 citations

Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria

1985 • 1,201 citations

MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES

1989 • 1,179 citations

Mechanism of myocardial "stunning".

1990 • 995 citations

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.

1996 • 976 citations

Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria

1977 • 854 citations

[42]Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

1996 • 746 citations

Stretch-induced programmed myocyte cell death.

1995 • 647 citations

Effect of anthracycline antibiotics on oxygen radical formation in rat heart.

1983 • 634 citations

Oxygen free radicals and congestive heart failure.

1991 • 540 citations

Evidence that mitochondrial respiration is a source of potentially toxic oxygen free radicals in intact rabbit hearts subjected to ischemia and reflow.

1993 • 518 citations

Elevated Levels of 8-iso-Prostaglandin F _2α in Pericardial Fluid of Patients With Heart Failure

1998 • 446 citations

Prostaglandins in Severe Congestive Heart Failure

1984 • 434 citations

Measurement and characterization of postischemic free radical generation in the isolated perfused heart

1989 • 383 citations

Antioxidant and oxidative stress changes during heart failure subsequent to myocardial infarction in rats.

1996 • 364 citations

NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH–ubiquinone reductase preparation

1979 • 293 citations

Study of the mechanisms of hydrogen peroxide and hydroxyl free radical-induced cellular injury and calcium overload in cardiac myocytes

1991 • 278 citations

Evidence of oxidative stress in chronic heart failure in humans

1993 • 277 citations

Right and Left Myocardial Antioxidant Responses During Heart Failure Subsequent to Myocardial Infarction

1997 • 271 citations

Interpretation of the thiobarbituric acid reactivity of rat liver and brain homogenates in the presence of ferric ion and ethylenediaminetetraacetic acid

1992 • 264 citations

Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine.

1981 • 247 citations

Report of the National Heart, Lung, and Blood Institute Special Emphasis Panel on Heart Failure Research

1997 • 221 citations

Hydroxyl Radical Generation During Mitochondrial Electron-Transfer and the Formation of 8-Hydroxydesoxyguanosine in Mitochondrial-DNA

1995 • 189 citations

Quantitative Measurement of Superoxide Generation Using the Spin Trap 5-(Diethoxyphosphoryl)-5-methyl- 1-pyrroline-N-oxide

1997 • 176 citations

Antioxidant changes in hypertrophied and failing guinea pig hearts

1994 • 160 citations

Characterization of Epitopes Recognized by 4-Hydroxy-2-nonenal Specific Antibodies

1995 • 138 citations

Detection of hydroxyl radical in the mitochondria of ischemic-reperfused myocardium by trapping with salicylate

1989 • 123 citations

Xanthine oxidoreductase activity in perfused hearts of various species, including humans.

1990 • 114 citations

Myocardial catecholamines and the pathophysiology of heart failure.

1990 • 105 citations

Oxygen free radicals and calcium homeostasis in the heart

1994 • 96 citations

Reactive oxygen intermediate(s) (ROI): Common mediator(s) of poly(ADP‐ribose)polymerase (PARP) cleavage and apoptosis

1996 • 96 citations

Influence of exogenously generated oxidant species on myocardial function

1986 • 90 citations

Role of Myocyte Nitric Oxide in β-Adrenergic Hyporesponsiveness in Heart Failure

1997 • 87 citations

Antioxidant Activity of Nitroxide Radicals in Lipid Peroxidation of Rat Liver Microsomes

1993 • 82 citations

Increased chemiluminescence of polymorphonuclear leucocytes in dogs with volume overload heart failure.

1989 • 35 citations

Role of Microtubules in the Contractile Dysfunction of Myocytes from Tachycardia-induced Dilated Cardiomyopathy

1998 • 27 citations