Nuclear control of respiratory chain expression in mammalian cells.

Activation of the human mitochondrial transcriptionfactor A gene by nuclear respiratory factors: a potential regulatory linkbetween nuclear and mitochondrial gene expression in organellebiogenesis.

1994 • 765 citations

An autosomal dominant disorder with multiple deletions of mitochondrial DNA starting at the D-loop region

1989 • 637 citations

mtDNA depletion with variable tissue expression: a novel genetic abnormality in mitochondrial diseases.

1991 • 588 citations

Similarity of Human Mitochondrial Transcription Factor 1 to High Mobility Group Proteins

1991 • 538 citations

MOLECULAR GENETIC ASPECTS OF HUMAN MITOCHONDRIAL DISORDERS

1995 • 486 citations

Convergence of Ets- and Notch-Related Structural Motifs in a Heteromeric DNA Binding Complex

1991 • 464 citations

Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer.

1989 • 432 citations

RTG1 and RTG2: Two yeast genes required for a novel path of communication from mitochondria to the nucleus

1993 • 414 citations

NRF-1: a trans-activator of nuclear-encoded respiratory genes in animal cells.

1990 • 404 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

Identification of Ets- and Notch-Related Subunits in GA Binding Protein

1991 • 358 citations

Transcription and Replication of Animal Mitochondrial DNAs

1992 • 356 citations

Purification and characterization of human mitochondrial transcription factor 1.

1988 • 352 citations

NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of developmental regulators.

1993 • 343 citations

A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria.

1991 • 325 citations

DNA wrapping and bending by a mitochondrial high mobility group-like transcriptional activator protein.

1992 • 322 citations

Termination of transcription in human mitochondria: Identification and purification of a DNA binding protein factor that promotes termination

1989 • 289 citations

Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promoters.

1993 • 285 citations

Cloning of yeast HAP5: a novel subunit of a heterotrimeric complex required for CCAAT binding.

1995 • 276 citations

Interaction of Nuclear Factors with Multiple Sites in the Somatic Cytochrome c Promoter

1989 • 259 citations

Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements

1987 • 253 citations

Impairment of mitochondrial transcription termination by a point mutation associated with the MELAS subgroup of mitochondrial encephalomyopathies

1991 • 234 citations

Low Levels of Mitochondrial Transcription Factor A in Mitochondrial DNA Depletion

1994 • 223 citations

A 43-kDa Protein Related to c-Erb A α1 Is Located in the Mitochondrial Matrix of Rat Liver

1995 • 198 citations

A human mitochondrial transcriptional activator can functionally replace a yeast mitochondrial HMG-box protein both in vivo and in vitro.

1993 • 184 citations

Mitochondrial transcription initiation. Variation and conservation

1993 • 184 citations

DNA binding properties of an HMG1-related protein from yeast mitochondria.

1992 • 175 citations

Adaptation of skeletal muscle to increased contractile activity. Expression nuclear genes encoding mitochondrial proteins.

1987 • 174 citations

Transcriptional activation through ETS domain binding sites in the cytochrome c oxidase subunit IV gene.

1991 • 159 citations

A single mouse gene encodes the mitochondrial transcription factor A and a testis–specific nuclear HMG-box protein

1996 • 147 citations

The mitochondrion as a primary site of action of glucocorticoids: the interaction of the glucocorticoid receptor with mitochondrial DNA sequences showing partial similarity to the nuclear glucocorticoid responsive elements

1995 • 129 citations

Purification and Characterization of Human Mitochondrial Transcription Factor 1

1988 • 128 citations

Flexible recognition of rapidly evolving promoter sequences by mitochondrial transcription factor 1.

1989 • 128 citations

Nuclear respiratory factor 1 activation sites in genes encoding the gamma-subunit of ATP synthase, eukaryotic initiation factor 2 alpha, and tyrosine aminotransferase. Specific interaction of purified NRF-1 with multiple target genes.

1992 • 126 citations

Neoplastic transformation is associated with coordinate induction of nuclear and cytoplasmic oxidative phosphorylation genes

1990 • 123 citations

Four Structurally Distinct, Non-DNA-Binding Subunits of Human Nuclear Respiratory Factor 2 Share a Conserved Transcriptional Activation Domain

1995 • 122 citations

Mitochondrial DNA expression in mitochondrial myopathies and coordinated expression of nuclear genes involved in ATP production

1993 • 109 citations

Transcriptional control of nuclear genes for the mitochondrial muscle ADP/ATP translocator and the ATP synthase beta subunit. Multiple factors interact with the OXBOX/REBOX promoter sequences.

1992 • 105 citations

Mitochondrial DNA Polymerase is Expressed and Translated in the Absence of Mitochondrial DNA Maintenance and Replication

1996 • 102 citations

cDNA Cloning of Transcription Factor E4TF1 Subunits with Ets and Notch Motifs

1993 • 99 citations

Differential regulation of respiratory chain subunits by a CREB-dependent signal transduction pathway. Role of cyclic AMP in cytochrome c and COXIV gene expression.

1994 • 99 citations

Existence of common homologous elements in the transcriptional regulatory regions of human nuclear genes and mitochondrial gene for the oxidative phosphorylation system

1991 • 97 citations

Molecular characterization of the transcription termination factor from human mitochondria.

1993 • 95 citations

The Drosophila erect wing Gene, Which Is Important for both Neuronal and Muscle Development, Encodes a Protein Which Is similar to the Sea Urchin P3A2 DNA Binding Protein

1993 • 90 citations

Nuclear Respiratory Factors 1 and 2 Utilize Similar Glutamine-Containing Clusters of Hydrophobic Residues To Activate Transcription

1996 • 88 citations

Identification of regulatory sequences in the gene for 5-aminolevulinate synthase from rat.

1993 • 85 citations

Cooperative binding of GA-binding protein transcription factors to duplicated transcription initiation region repeats of the cytochrome c oxidase subunit IV gene.

1994 • 85 citations

Inhibition of mitochondrial protein synthesis promotes increased stability of nuclear-encoded respiratory gene transcripts.

1994 • 84 citations

The basal promoter elements of murine cytochrome c oxidase subunit IV gene consist of tandemly duplicated ets motifs that bind to GABP-related transcription factors

1992 • 84 citations

Distinct Roles for Two Purified Factors in Transcription of Xenopus Mitochondrial DNA

1995 • 83 citations

Both upstream and intron sequence elements are required for elevated expression of the rat somatic cytochrome c gene in COS-1 cells.

1988 • 82 citations

Import of the glucocorticoid receptor into rat liver mitochondria in vivo and in vitro

1993 • 78 citations

Common protein-binding sites in the 5'-flanking regions of human genes for cytochrome c1 and ubiquinone-binding protein.

1990 • 77 citations

OXBOX, a positive transcriptional element of the heart-skeletal muscle ADP/ATP translocator gene

1990 • 76 citations

Signal transduction pathways that regulate skeletal muscle gene expression.

1993 • 73 citations

Nuclear respiratory factors and the pathways of nuclear-mitochondrial interaction

1996 • 72 citations

Differential regulation of expression of the multiple ADP/ATP translocase genes in human cells.

1991 • 67 citations

Structure, Expression, and Chromosomal Assignment of the Human Gene Encoding Nuclear Respiratory Factor 1

1995 • 67 citations

A Human Mitochondrial Transcriptional Activator Can Functionally Replace a Yeast Mitochondrial HMG-box Protein Both In Vivo and In Vitro

1993 • 66 citations

Redox Regulation of GA-binding Protein-α DNA Binding Activity

1996 • 65 citations

Tissue-specific genes for respiratory proteins

1989 • 65 citations

Novel regulatory enhancer in the nuclear gene of the human mitochondrial ATP synthase beta-subunit.

1990 • 62 citations

Nuclear responses to depletion of mitochondrial DNA in human cells

1995 • 62 citations

Cytochrome c Oxidase Subunit VIIa Liver Isoform

1996 • 62 citations

Mitochondrial transcription: is a pattern emerging?

1993 • 61 citations

Coordinate induction of multiple cytochrome c mRNAs in response to thyroid hormone.

1986 • 58 citations

OXBOX and REBOX, overlapping promoter elements of the mitochondrial F0F1-ATP synthase beta subunit gene. OXBOX/REBOX in the ATPsyn beta promoter.

1994 • 57 citations

Structural Characterization and Regulatory Element Analysis of the Heart Isoform of Cytochrome c Oxidase VIa

1995 • 57 citations

The GA-binding Protein Can Serve as Both an Activator and Repressor of ribosomal protein Gene Transcription

1996 • 55 citations

ETS transcription factors regulate the expression of the gene for the human mitochondrial ATP synthase beta-subunit.

1994 • 44 citations

In organello footprinting. Analysis of protein binding at regulatory regions in bovine mitochondrial DNA.

1993 • 44 citations

Gene regulatory factors of the sea urchin embryo: II. Two dissimilar proteins, P3A1 and P3A2, bind to the same target sites that are required for early territorial gene expression

1991 • 42 citations

G Proteins

1992 • 40 citations

Comparative utilization of transcription factor GABP by the promoters of ribosomal protein genes rpL30 and rpL32.

1993 • 40 citations

Initiation Binding Receptor, a Factor That Binds to the Transcription Initiation Site of the Histone h5 Gene, Is a Glycosylated Member of a Family of Cell Growth Regulators

1995 • 38 citations

Differentially expressed mRNAs as a consequence of oxidative stress in intact cells

1995 • 35 citations

The Role of an E Box Binding Basic Helix Loop Helix Protein in the Cardiac Muscle-specific Expression of the Rat Cytochrome Oxidase Subunit VIII Gene

1996 • 30 citations

Phylogenetic Footprinting of the Human Cytochrome c Oxidase Subunit Vb Promoter

1996 • 26 citations

Intracellular dialogue

1993 • 24 citations

Hormonal Regulation of Cytochrome Oxidase Subunit Messenger RNAs in Rat Sertoli Cells

1991 • 23 citations

Both Upstream and Intron Sequence Elements Are Required for Elevated Expression of the Rat Somatic Cytochrome c Gene in COS-1 Cells

1988 • 21 citations

Transcriptional Activation through ETS Domain Binding Sites in the Cytochrome c Oxidase Subunit IV Gene

1991 • 17 citations

Human Nuclear and Mitochondrial Mt Element-Binding Proteins to Regulatory Regions of the Nuclear Respiratory Genes and to the Mitochondrial Promoter Region

1995 • 17 citations

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