The BMP Homolog Gbb Provides a Retrograde Signal that Regulates Synaptic Growth at the Drosophila Neuromuscular Junction

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Neurotrophins: Roles in Neuronal Development and Function

2001 • 4,134 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders

2000 • 2,354 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

1995 • 1,354 citations

Endocannabinoid Signaling in the Brain

2002 • 1,240 citations

Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice

1996 • 1,219 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor

1998 • 952 citations

Improved stability of Drosophila larval neuromuscular preparations in haemolymph-like physiological solutions

1994 • 828 citations

Postsynaptic Signaling and Plasticity Mechanisms

2002 • 713 citations

Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance

1994 • 690 citations

Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of drosophila

1995 • 681 citations

wishful thinking Encodes a BMP Type II Receptor that Regulates Synaptic Growth in Drosophila

2002 • 520 citations

Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. I. Fasciclin II Controls Synaptic Stabilization and Growth

1996 • 515 citations

Genetic Analysis of Glutamate Receptors in Drosophila Reveals a Retrograde Signal Regulating Presynaptic Transmitter Release

1997 • 477 citations

Endocytosis of Activated TrkA: Evidence that Nerve Growth Factor Induces Formation of Signaling Endosomes

1996 • 434 citations

Cells compete for Decapentaplegic survival factor to prevent apoptosis in Drosophila wing development

2002 • 432 citations

The Drosophila Wnt, Wingless, Provides an Essential Signal for Pre- and Postsynaptic Differentiation

2002 • 416 citations

Regulation of Synapse Structure and Function by the Drosophila Tumor Suppressor Gene dlg

1996 • 411 citations

Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. II. Fasciclin II Controls Presynaptic Structural Plasticity

1996 • 372 citations

Cytoplasmic Dynein, the Dynactin Complex, and Kinesin Are Interdependent and Essential for Fast Axonal Transport

1999 • 365 citations

Quantitative Imaging of Lateral ErbB1 Receptor Signal Propagation in the Plasma Membrane

2000 • 346 citations

The Drosophila BMP Type II Receptor Wishful Thinking Regulates Neuromuscular Synapse Morphology and Function

2002 • 330 citations

TGF-β Family Signal Transduction in Drosophila Development: From Mad to Smads

1999 • 324 citations

Retrograde neurotrophin signaling: Trk-ing along the axon

2002 • 313 citations

Twisted gastrulation is a conserved extracellular BMP antagonist

2001 • 302 citations

TGFβ receptor internalization into EEA1-enriched early endosomes

2002 • 298 citations

Glutamate Receptor Expression Regulates Quantal Size and Quantal Content at theDrosophilaNeuromuscular Junction

1999 • 297 citations

Rapid Nuclear Responses to Target-Derived Neurotrophins Require Retrograde Transport of Ligand–Receptor Complex

1999 • 278 citations

Dynactin Is Necessary for Synapse Stabilization

2002 • 255 citations

Unrestricted Synaptic Growth in spinster—a Late Endosomal Protein Implicated in TGF-β-Mediated Synaptic Growth Regulation

2002 • 253 citations

A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis

1990 • 251 citations

Homeostatic Control of Presynaptic Release Is Triggered by Postsynaptic Membrane Depolarization

2001 • 247 citations

Retrograde Support of Neuronal Survival Without Retrograde Transport of Nerve Growth Factor

2002 • 247 citations

Synapse-specific control of synaptic efficacy at the terminals of a single neuron

1998 • 239 citations

TGF-β Signaling Activates Steroid Hormone Receptor Expression during Neuronal Remodeling in the Drosophila Brain

2003 • 230 citations

Retrograde Signaling in the Development and Modification of Synapses

1998 • 227 citations

Watching a Synapse Grow

1999 • 227 citations

Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila

1998 • 218 citations

Retrograde signaling by endocannabinoids

2002 • 217 citations

Wingless Signaling InducesnautilusExpression in the Ventral Mesoderm of theDrosophilaEmbryo

1996 • 214 citations

The screw gene encodes a ubiquitously expressed member of the TGF-beta family required for specification of dorsal cell fates in the Drosophila embryo.

1994 • 199 citations

The Drosophila Activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development

1999 • 190 citations

Association of Trk Neurotrophin Receptors with Components of the Cytoplasmic Dynein Motor

2001 • 188 citations

Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway

2002 • 187 citations

Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis

1994 • 180 citations

Functions of cannabinoid receptors in the hippocampus

2002 • 178 citations

Potentiation of Developing Synapses by Postsynaptic Release of Neurotrophin-4

1997 • 176 citations

Molecular Evolution of a Developmental Pathway: Phylogenetic Analyses of Transforming Growth Factor-β Family Ligands, Receptors and Smad Signal Transducers

1999 • 175 citations

Retrograde Control of Synaptic Transmission by Postsynaptic CaMKII at the Drosophila Neuromuscular Junction

2003 • 164 citations

Rapid Retrograde Tyrosine Phosphorylation of trkA and Other Proteins in Rat Sympathetic Neurons in Compartmented Cultures

1997 • 163 citations

On Trk for Retrograde Signaling

2001 • 161 citations

Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins.

1991 • 159 citations

Homeostasis of synaptic transmission in Drosophila with genetically altered nerve terminal morphology.

1996 • 158 citations

TGF-β/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing

1998 • 156 citations

The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF‐β/Smad signalling

2002 • 150 citations

Homeostasis of Synaptic Transmission inDrosophilawith Genetically Altered Nerve Terminal Morphology

1996 • 137 citations

Retrograde signaling at central synapses

2001 • 136 citations

TGF‐β receptors

1992 • 133 citations

Genetic analysis of synaptic development and plasticity: homeostatic regulation of synaptic efficacy

1998 • 131 citations

Developmental Changes in the Transmitter Properties of Sympathetic Neurons That Innervate the Periosteum

2000 • 123 citations

Interpretation of a BMP Activity Gradient in Drosophila Embryos Depends on Synergistic Signaling by Two Type I Receptors, SAX and TKV

1998 • 122 citations

Receptor binding, internalization, and retrograde transport of neurotrophic factors

2001 • 115 citations

Sequence, biochemical characterization, and developmental expression of a new member of the TGF-β superfamily in Drosophila melanogaster

1992 • 111 citations

Synaptic plasticity: A role for nitric oxide in LTP

1997 • 104 citations

Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-β superfamily

1999 • 94 citations

Molecular mechanisms that underlie structural and functional changes atthe postsynaptic membrane duringsynaptic plasticity

1998 • 91 citations

Context-dependent relationships between the BMPsgbbanddppduring development of theDrosophilawing imaginal disk

2001 • 89 citations

Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development

1999 • 84 citations

CRC Handbook of Mathematical Sciences

1978 • 79 citations

Extracellular matrix molecules, long-term potentiation, memory consolidation and the brain angiotensin system

2002 • 75 citations

Long-term regulation of short-term transmitter release properties: retrograde signaling and synaptic development

1994 • 68 citations

A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration.

1996 • 62 citations

A Sweat Gland-derived Differentiation Activity Acts through Known Cytokine Signaling Pathways

1997 • 61 citations

Mutant molecular motors disrupt neural circuits inDrosophila

1997 • 48 citations

Transforming Growth Factor β Receptor Signaling and Endocytosis Are Linked through a COOH Terminal Activation Motif in the Type I Receptor

2001 • 48 citations

The relationship between adhesion molecules and neuronal plasticity.

1998 • 43 citations

Identification of maverick , a novel member of the TGF-β superfamily in Drosophila

2000 • 39 citations

Retrograde signaling and the development of transmitter release properties in the invertebrate nervous system

1994 • 38 citations

The range of spalt-activating Dpp signalling is reduced in endocytosis-defective Drosophila wing discs

1999 • 31 citations

Differential regulation of adrenergic receptor development by sympathetic innervation

1996 • 21 citations

Control of postganglionic neurone phenotype by the rat pineal gland

2002 • 18 citations

Synaptic plasticity: Keeping synapses under control

1998 • 13 citations