Sequence, biochemical characterization, and developmental expression of a new member of the TGF-β superfamily in Drosophila melanogaster

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The embryonic development of Drosophila melanogaster

1938 • 2,188 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

The Embryonic Development of Drosophila melanogaster

1985 • 1,371 citations

Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

1986 • 1,148 citations

Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin

1986 • 1,071 citations

Isolation of the bovine and human genes for müllerian inhibiting substance and expression of the human gene in animal cells

1986 • 997 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates

1987 • 966 citations

Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

1990 • 837 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

Mammalian subtilisins: The long-sought dibasic processing endoproteases

1991 • 756 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

1985 • 722 citations

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

1990 • 675 citations

Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A

1990 • 660 citations

Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A)

1990 • 616 citations

Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures

1990 • 600 citations

OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.

1990 • 554 citations

The cell biology of transforming growth factor β

1990 • 537 citations

Assembly of the Mitochondrial Membrane System

1971 • 507 citations

Assembly of the mitochondrial membrane system. CBP6, a yeast nuclear gene necessary for synthesis of cytochrome b.

1985 • 467 citations

Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice.

1989 • 451 citations

Characterization and use of theDrosophilametallothionein promoter in culturedDrosophila melanogastercells

1988 • 440 citations

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development.

1989 • 440 citations

Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis.

1987 • 422 citations

A new type of transforming growth factor-beta, TGF-beta 3.

1988 • 396 citations

A simple, rapid method for the purification of poly A+ RNA.

1988 • 382 citations

Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster

1982 • 345 citations

Identification and immunochemical analysis of biologically active Drosophila P element transposase

1986 • 318 citations

Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells

1989 • 291 citations

The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo.

1987 • 288 citations

Cloning and sequence analysis of cDNA species coding for the two subunits of inhibin from bovine follicular fluid.

1986 • 273 citations

Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos

1990 • 265 citations

A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis

1990 • 251 citations

Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements.

1990 • 250 citations

Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo.

1987 • 247 citations

The control of cell fate along the dorsal-ventral axis of the Drosophila embryo

1991 • 246 citations

Genetic analysis of pattern formation in the Arabidopsis embryo

1991 • 244 citations

Complementary Deoxyribonucleic Acid Cloning of a Messenger Ribonucleic Acid Encoding Transforming Growth Factor β 4 from Chicken Embryo Chondrocytes

1988 • 227 citations

Expression of transforming growth factor β2 RNA during murine embryogenesis

1989 • 202 citations

Molecular organization of the decapentaplegic gene in Drosophila melanogaster.

1990 • 201 citations

Oxygen binding properties of human mutant hemoglobins synthesized in Escherichia coli.

1985 • 201 citations

Transforming Growth Factor-β2: cDNA Cloning and Sequence Analysis

1988 • 200 citations

Drosophila: A practical approach

1987 • 196 citations

Differential expression of genes encoding TGFs β1, β2, and β3 during murine palate formation

1990 • 195 citations

Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis.

1990 • 177 citations

Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily.

1989 • 176 citations

Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary

1990 • 170 citations

An Ultrabithorax protein binds sequences near its own and the Antennapedia P1 promoters

1988 • 166 citations

The DVR gene family in embryonic development

1991 • 159 citations

The decapentaplegic gene: a TGF-β homologue controlling pattern formation in Drosophila

1989 • 144 citations

A Mouse Macrophage Factor Induces Head Structures and Organizes a Body Axis in Xenopus

1990 • 130 citations

Transforming Growth Factor

2008 • 121 citations

Regulated expression at high copy number allows production of a growth-inhibitory oncogene product in Drosophila Schneider cells.

1989 • 111 citations

Vectors containing a prokaryotic dihydrofolate reductase gene transform Drosophila cells to methotrexate-resistance.

1983 • 109 citations

Cloning and Sequence Analysis of Simian Transforming Growth Factor-β cDNA

1987 • 95 citations

The DVR gene family in embryonic development

1991 • 84 citations

Localized cell death caused by mutations in a Drosophila gene coding for a transforming growth factor-β homolog

1988 • 79 citations

Biochemical characterization of the Drosophila dpp protein, a member of the transforming growth factor beta family of growth factors.

1990 • 78 citations

The relationship of decapentaplegic and engrailed expression in Drosophila imaginal disks: do these genes mark the anterior-posterior compartment boundary?

1991 • 72 citations

Genetics of pattern formation and growth control

1991 • 58 citations

Assembly of the mitochondrial membrane system

1980 • 38 citations

Transforming growth factor-β-related genes in Drosophila and vertebrate development

1991 • 22 citations