Two Functional Coding Single Nucleotide Polymorphisms in STK15 (Aurora-A) Coordinately Increase Esophageal Cancer Risk

The Sequence of the Human Genome

2001 • 13,500 citations

Locally Weighted Regression: An Approach to Regression Analysis by Local Fitting

1988 • 5,073 citations

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

2002 • 3,503 citations

The Sequence of the Human Genome

2015 • 1,654 citations

Mitotic kinases as regulators of cell division and its checkpoints

2001 • 1,503 citations

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint

2003 • 1,144 citations

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

2004 • 944 citations

The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

2000 • 713 citations

Aurora-A and an Interacting Activator, the LIM Protein Ajuba, Are Required for Mitotic Commitment in Human Cells

2003 • 610 citations

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

1997 • 483 citations

Cancer genetics

2001 • 421 citations

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

2003 • 318 citations

Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190 562 genetic variations in the human genome

2002 • 301 citations

Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit

2002 • 295 citations

Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1

1997 • 265 citations

Determination of Single-Nucleotide Polymorphisms by Real-time Pyrophosphate DNA Sequencing

2000 • 265 citations

On the role of aurora-A in centrosome function

2002 • 223 citations

Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

2001 • 211 citations

Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway

2000 • 146 citations

The centrosomal protein Lats2 is a phosphorylation target of Aurora‐A kinase

2004 • 138 citations

Genetics and the common cancers

2001 • 121 citations

Structure, Expression, and Chromosome Mapping of LATS2, a Mammalian Homologue of the Drosophila Tumor Suppressor Gene lats/warts

2000 • 102 citations

Functional STK15 Phe31Ile Polymorphism Is Associated with the Occurrence and Advanced Disease Status of Esophageal Squamous Cell Carcinoma

2004 • 83 citations

A subset of skin tumor modifier loci determines survival time of tumor-bearing mice

1999 • 75 citations

Searching for cancer-associated gene polymorphisms: promises and obstacles

2003 • 73 citations

STK15 Polymorphisms and Association with Risk of Invasive Ovarian Cancer

2004 • 70 citations

Inhibition of Cell Growth by Conditional Expression of kpm, a Human Homologue of Drosophila warts/lats Tumor Suppressor

2003 • 67 citations

Molecular cloning of a novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor

2000 • 65 citations

Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme

2004 • 58 citations

STK15 polymorphism and breast cancer risk in a population-based study

2004 • 57 citations

Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice.

2003 • 51 citations

Frequent polymorphic changes but rare tumor specific mutations of the LATS2 gene on 13q11-12 in esophageal squamous cell carcinoma

2002 • 22 citations

Deleted Work

1955 • 0 citations