STK15 Polymorphisms and Association with Risk of Invasive Ovarian Cancer

Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.

1995 • 1,977 citations

Prophylactic Oophorectomy in Carriers ofBRCA1orBRCA2Mutations

2002 • 1,448 citations

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

Risk-Reducing Salpingo-oophorectomy in Women with aBRCA1orBRCA2Mutation

2002 • 1,229 citations

Population stratification and spurious allelic association

2003 • 1,214 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

Polygenic susceptibility to breast cancer and implications for prevention

2002 • 902 citations

Ovarian Cancer

1995 • 573 citations

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

1997 • 483 citations

Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer.

2000 • 319 citations

Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases

1999 • 318 citations

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

2003 • 318 citations

Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast.

1999 • 306 citations

Genetic analysis of benign, low-grade, and high-grade ovarian tumors.

1995 • 299 citations

Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1

1997 • 265 citations

Association of centrosomal kinaseSTK15/BTAK mRNA expression with chromosomal instability in human breast cancers

2001 • 231 citations

Genetic analysis of early- versus late-stage ovarian tumors.

2001 • 201 citations

Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q26, 8q24, and 20q13 in human ovarian carcinomas

1997 • 193 citations

Crystal Structure of Aurora-2, an Oncogenic Serine/Threonine Kinase

2002 • 191 citations

A simple mouthwash method for obtaining genomic DNA in molecular epidemiological studies.

1998 • 186 citations

NIH consensus conference. Ovarian cancer. Screening, treatment, and follow-up. NIH Consensus Development Panel on Ovarian Cancer

1995 • 154 citations

Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas.

2003 • 146 citations

Overrepresentation of 3q and 8q material and loss of 18q material are recurrent findings in advanced human ovarian cancer

1996 • 130 citations

Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft.

2002 • 121 citations

Comparative genomic hybridization detects genetic imbalances in primary ovarian carcinomas as correlated with grade of differentiation

2001 • 108 citations

Genetic Aberrations Detected by Comparative Genomic Hybridization in Ovarian Clear Cell Adenocarcinomas

2000 • 76 citations

The genetics of ovarian cancer

2002 • 73 citations

Genetic changes in inherited and sporadic ovarian carcinomas by comparative genomic hybridization: extensive similarity except for a difference at chromosome 2q24-q32.

1998 • 67 citations

Oral contraceptives and ovarian cancer

1999 • 61 citations

Differentially Regulated Genes as Putative Targets of Amplifications at 20q in Ovarian Cancers

2002 • 55 citations

Recurrent chromosome alterations in primary ovarian carcinoma in Chinese women

2002 • 50 citations

Analysis of ovarian borderline tumors using comparative genomic hybridization and fluorescence in situ hybridization

1999 • 44 citations

BRCA1/2 mutation status influences somatic genetic progression in inherited and sporadic epithelial ovarian cancer cases.

2003 • 44 citations

Assignment of STK6 to human chromosome 20q13.2→q13.3 and a pseudogene STK6P to 1q41→q42

1997 • 24 citations