Growth factor–induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen

Matrix Metalloproteinases

1999 • 3,774 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

Clinical Applications of Research on Angiogenesis

1995 • 2,300 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover

1999 • 1,280 citations

Angiogenesis and Tumor Metastasis

1998 • 1,013 citations

Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice

1999 • 990 citations

Tumor Induction of VEGF Promoter Activity in Stromal Cells

1998 • 964 citations

The Discoidin Domain Receptor Tyrosine Kinases Are Activated by Collagen

1997 • 956 citations

Matrix Metalloproteinase-2 Is an Interstitial Collagenase

1995 • 917 citations

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice.

1998 • 887 citations

Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

1999 • 840 citations

Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations.

1990 • 838 citations

Matrix Metalloproteinases Regulate Neovascularization by Acting as Pericellular Fibrinolysins

1998 • 716 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

Synergistic Effect of Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor on Angiogenesis In Vivo

1995 • 605 citations

The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix

1997 • 600 citations

Tumor targeting with a selective gelatinase inhibitor

1999 • 554 citations

Angiogenesis promoted by vascular endothelial growth factor: Regulation through α₁β₁and α₂β₁ integrins

1997 • 516 citations

An Orphan Receptor Tyrosine Kinase Family Whose Members Serve as Nonintegrin Collagen Receptors

1997 • 510 citations

Identification of an Inhibitor of Neovascularization from Cartilage

1990 • 481 citations

Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels.

1993 • 463 citations

The cell biology of leukocyte-mediated proteolysis

1999 • 424 citations

Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2

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Proteolysis and cell migration: creating a path?

1999 • 389 citations

The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.

1989 • 388 citations

Quantitative angiogenesis assays: Progress and problems

1997 • 386 citations

Three-dimensional Type I Collagen Lattices Induce Coordinate Expression of Matrix Metalloproteinases MT1-MMP and MMP-2 in Microvascular Endothelial Cells

1998 • 358 citations

Intracellular Pool of Vascular Endothelial Growth Factor in Human Neutrophils

1997 • 344 citations

Plasminogen Activators and Matrix Metalloproteinases in Angiogenesis

1996 • 341 citations

Affinity of integrins for damaged extracellular matrix: αvβ3 binds to denatured collagen type I through RGD sites

1992 • 326 citations

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase

1994 • 299 citations

A targeted mutation at the known collagenase cleavage site in mouse type I collagen impairs tissue remodeling.

1995 • 280 citations

Recent advances in matrix metalloproteinase inhibitor research

1996 • 279 citations

TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis

1998 • 274 citations

Quantitation of Angiogenesis and Antiangiogenesis in the Chick Embryo Chorioallantoic Membrane

1994 • 246 citations

Analysis of alpha 1 beta 1, alpha 2 beta 1 and alpha 3 beta 1 integrins in cell--collagen interactions: identification of conformation dependent alpha 1 beta 1 binding sites in collagen type I.

1992 • 218 citations

Assays for angiogenesis: A review

1991 • 202 citations

Regulation of Angiogenesis

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Generation of collagenase-resistant collagen by site-directed mutagenesis of murine pro alpha 1(I) collagen gene.

1990 • 121 citations

Endothelial Cell Biology in Health and Disease

1988 • 118 citations

Controlling tumor angiogenesis and metastasis of C26 murine colon adenocarcinoma by a new matrix metalloproteinase inhibitor, KB-R7785, in two tumor models.

1999 • 107 citations

Folding and characterization of the amino‐terminal domain of human tissue inhibitor of metalloproteinases‐1 (TIMP‐1) expressed at high yield in E. coli

1996 • 101 citations

The Role of αv Integrins during Angiogenesis

1998 • 100 citations

The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells.

1999 • 96 citations

Role of the macrophage in angiogenesis-dependent diseases

1997 • 90 citations

The monoclonal antibody CVI-CHNL-68.1 recognizes cells of the monocyte-macrophage lineage in chickens

1988 • 85 citations

Cloning and Characterization of a Novel Matrix Metalloproteinase (MMP), CMMP, from Chicken Embryo Fibroblasts

1998 • 67 citations

Collagenolytic cleavage products of collagen type I as chemoattractants for human dermal fibroblasts.

1985 • 65 citations

The Isolation, Characterization, and Molecular Cloning of a 75-kDa Gelatinase B-like Enzyme, a Member of the Matrix Metalloproteinase (MMP) Family

2000 • 55 citations

Cloning of a 72 kDa matrix metalloproteinase (gelatinase) from chicken embryo fibroblasts using gene family PCR: expression of the gelatinase increases upon malignant transformation

1994 • 42 citations

Interstitial Collagenases

1998 • 39 citations

Cloning and Developmental Expression of a Membrane-type Matrix Metalloproteinase from Chicken

1996 • 37 citations

Recruitment of Peripheral Mononuclear Cells by Mammalian Collagenase Digests of Type I Collagen

1991 • 31 citations

Endothelial Cell-Extracellular Matrix Interactions

1988 • 27 citations

Induction of Matrix Metalloproteinases and Collagenolysis in Chick Embryonic Membranes before Hatching1

1999 • 26 citations

A Simple Vessel for the Culture of Chicken Embryos Used in Angiogenesis Assays

1993 • 12 citations

What Structure and Function of Avian Plasminogen Activator and Matrix Metalloproteinase-2 Reveal about Their Counterpart Mammalian Enzymes, Their Regulation and Their Role in Tumor Invasion

1996 • 10 citations