Developmental changes in the expression of ATP7A during a critical period in postnatal neurodevelopment

Neurodegenerative diseases and oxidative stress

2004 • 3,422 citations

The Wilson disease gene is a putative copper transporting P–type ATPase similar to the Menkes gene

1993 • 1,905 citations

Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper–transporting ATPase

1993 • 1,395 citations

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

1993 • 1,345 citations

The metallobiology of Alzheimer's disease

2003 • 1,256 citations

The S100 protein family: History, function, and expression

1995 • 930 citations

C<scp>ERULOPLASMIN</scp> M<scp>ETABOLISM AND</scp> F<scp>UNCTION</scp>

2002 • 850 citations

The Role of Copper in Neurodegenerative Disease

1999 • 833 citations

Characterization of a cis-Golgi matrix protein, GM130.

1995 • 797 citations

COPPER-ZINC SUPEROXIDE DISMUTASE AND AMYOTROPHIC LATERAL SCLEROSIS

2003 • 749 citations

A Delicate Balance: Homeostatic Control of Copper Uptake and Distribution

1999 • 715 citations

Molecular mechanisms of copper uptake and distribution

2002 • 681 citations

Adaptable adaptors for coated vesicles

2004 • 672 citations

Isolation and Characterization of a Human Liver cDNA as a Candidate Gene for Wilson Disease

1993 • 501 citations

Mapping, cloning and genetic characterization of the region containing the Wilson disease gene

1993 • 489 citations

New insights into copper monooxygenases and peptide amidation: structure, mechanism and function

2000 • 447 citations

Neurotrophic protein S100 beta stimulates glial cell proliferation.

1991 • 326 citations

NMDA Receptor Activation Mediates Copper Homeostasis in Hippocampal Neurons

2005 • 279 citations

Molecular Mechanisms of Copper Homeostasis

1999 • 260 citations

Ependymal development, proliferation, and functions: A review

1998 • 253 citations

The Menkes copper transporter is required for the activation of tyrosinase

2000 • 213 citations

Functional Electron Microscopy of the Hypothalamic Median Eminence

1970 • 210 citations

Function and Regulation of the Mammalian Copper-transporting ATPases: Insights from Biochemical and Cell Biological Approaches

2003 • 206 citations

The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system

2005 • 205 citations

Null Mutation of the Murine ATP7B (Wilson Disease) Gene Results in Intracellular Copper Accumulation and Late-Onset Hepatic Nodular Transformation

1999 • 195 citations

The Class B Scavenger Receptor CD36 Mediates Free Radical Production and Tissue Injury in Cerebral Ischemia

2005 • 187 citations

Copper Chelation Delays the Onset of Prion Disease

2003 • 183 citations

Respiration and Parturition Affected by Conditional Overexpression of the Ca ²⁺ -Activated K ⁺ Channel Subunit, SK3

2000 • 182 citations

Evidence for a satellite secretory pathway in neuronal dendritic spines

2001 • 177 citations

The Copper-transporting ATPases, Menkes and Wilson Disease Proteins, Have Distinct Roles in Adult and Developing Cerebellum

2005 • 173 citations

Neuropathology of status epilepticus in humans.

1983 • 166 citations

Integrin-linked kinase is required for laminin-2–induced oligodendrocyte cell spreading and CNS myelination

2003 • 164 citations

The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment

2001 • 150 citations

Cellular distribution of superoxide dismutases in the rat CNS

2000 • 149 citations

A C-terminal di-leucine is required for localization of the Menkes protein in the trans-Golgi network

1998 • 148 citations

Chapter 14 S100β as a neurotrophic factor

1990 • 141 citations

Copper-regulated Trafficking of the Menkes Disease Copper ATPase Is Associated with Formation of a Phosphorylated Catalytic Intermediate

2002 • 134 citations

FGF-2 converts mature oligodendrocytes to a novel phenotype

1997 • 128 citations

Macrophages/microglial cells in human central nervous system during development: an immunohistochemical study

1998 • 127 citations

Diagnosis and therapy of Menkes syndrome, a genetic form of copper deficiency

1998 • 125 citations

Altered copper metabolism in cultured cells from human Menkes' syndrome and mottled mouse mutants

1980 • 121 citations

Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice

1994 • 119 citations

Correction of the Copper Transport Defect of Menkes Patient Fibroblasts by Expression of the Menkes and Wilson ATPases

1998 • 114 citations

Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia

2004 • 112 citations

An immunohistochemical study of copper/zinc superoxide dismutase and manganese superoxide dismutase in rat hippocampus after transient cerebral ischemia

1993 • 100 citations

Role of human fetal ependyma

1992 • 96 citations

Menkes Protein Contributes to the Function of Peptidylglycine α-Amidating Monooxygenase

2002 • 94 citations

Gradation of Kainic Acid-induced Rat Limbic Seizures and Expression of Hippocampal Heat Shock Protein-70

1997 • 94 citations

Menkes disease: recent advances and new aspects.

1997 • 94 citations

Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters

1997 • 93 citations

Menkes Copper ATPase (Atp7a) Is a Novel Metal-responsive Gene in Rat Duodenum, and Immunoreactive Protein Is Present on Brush-border and Basolateral Membrane Domains

2005 • 90 citations

Functional analysis and intracellular localization of the human menkes protein (MNK) stably expressed from a cDNA construct in Chinese hamster ovary cells (CHO-K1)

1998 • 89 citations

Mutation Analysis and Expression of the Mottled Gene in the Macular Mouse Model of Menkes Disease

1997 • 88 citations

Copper metabolism in mottled mouse mutants: copper therapy of brindled (Mobr) mice

1979 • 86 citations

Identification of a di-leucine motif within the C terminus domain of the Menkes disease protein that mediates endocytosis from the plasma membrane

1999 • 84 citations

Molecular and Cellular Aspects of Copper Transport in Developing Mammals

2003 • 83 citations

Histochemistry and immunocytochemistry of the developing ependyma and choroid plexus

1998 • 81 citations

Fine Structure of the Cerebellar Cortex in Menkes Kinky-Hair Disease

1977 • 73 citations

Copper Efflux from Murine Microvascular Cells Requires Expression of the Menkes Disease Cu-ATPase

1998 • 72 citations

Localization of integral membrane peptidylglycine alpha-amidating monooxygenase in neuroendocrine cells

1997 • 71 citations

Tanycytes Present in the Adult Rat Mediobasal Hypothalamus Support the Regeneration of Monoaminergic Axons

1998 • 69 citations

Intracellular localization of the Menkes and Wilson's disease proteins and their role in intracellular copper transport

1999 • 66 citations

Secretory carrier membrane proteins interact and regulate trafficking of the organellar (Na+,K+)/H+ exchanger NHE7

2005 • 65 citations

Expression of Brain-Derived Neurotrophic Factor and Its Receptors in the Median Eminence Cells with Sensitivity to Stress

2004 • 62 citations

Intracellular localization and loss of copper responsiveness of Mnk, the murine homologue of the Menkes protein, in cells from blotchy (Mo blo) and brindled (Mo br) mouse mutants

1999 • 60 citations

Transected axons of adult hypothalamo‐neurohypophysial neurons regenerate along tanycytic processes

1995 • 60 citations

Copper‐replacement treatment for symptomatic Menkes disease: ethical considerations

2005 • 59 citations

Novel membrane traffic steps regulate the exocytosis of the Menkes disease ATPase

2002 • 54 citations

Downregulation of myelination, energy, and translational genes in Menkes disease brain

2005 • 53 citations

The Developmentally Regulated Expression of Menkes Protein ATP7A Suggests a Role in Axon Extension and Synaptogenesis

2005 • 52 citations

Localization of Menkes gene expression in the mouse brain; its association with neurological manifestations in Menkes model mice

1996 • 50 citations

Polydendritic purkinje cells in X-chromosome linked copper malabsorption: a Golgi study

1976 • 49 citations

Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

2004 • 48 citations

Differential expression of two NMDA receptor interacting proteins, PSD‐95 and SynGAP during mouse development

2005 • 48 citations

Distinct spatiotemporal expression of mRNAs for the PSD-95/SAP90 protein family in the mouse brain

1999 • 47 citations

Relationship of glia to GnRH axonal outgrowth from third ventricular grafts in hpg hosts

1991 • 47 citations

Degeneration of the cerebellar system in X‐chromosome—linked copper malabsorption

1979 • 45 citations

Polarized Distribution of the Trans‐Golgi Network Marker TGN38 During the In Vitro Development of Neocortical Neurons: Effects of Nocodazole and Brefeldin A

1994 • 43 citations

Peptidylglycine alpha-amidating monooxygenase (PAM) in Schwann cells and glia as well as neurons.

1990 • 43 citations

Localization of immunoreactive prolactin in ependyma and circumventricular organs of rat brain

1982 • 42 citations

The Menkes disease ATPase (ATP7A) is internalized via a Rac1-regulated, clathrin- and caveolae-independent pathway

2003 • 41 citations

The Effect of Copper Supplementation on the Brindled Mouse

1981 • 40 citations

Stage Specific, (04&lt;sup&gt;+&lt;/sup&gt;GalC&lt;sup&gt;–&lt;/sup&gt;) Isolated Oligodendrocyte Progenitors Produce MBP&lt;sup&gt;+&lt;/sup&gt; Myelin in vivo

1992 • 37 citations

Tanycytes Transplanted into the Adult Rat Spinal Cord Support the Regeneration of Lesioned Axons

2000 • 35 citations

Cell Type-Specific Metabolism of Peptidylglycineα -Amidating Monooxygenase in Anterior Pituitary*

2000 • 32 citations

Expression of Trio, a member of the Dbl family of Rho GEFs in the developing rat brain

2005 • 30 citations

Biochemical Study on the Critical Period for Treatment of the Mottled Brindled Mouse

1990 • 29 citations

Neuropeptide precursor processing detected by triple immunolabeling

1999 • 23 citations

Morphology of the ependymal lining of the rabbit third ventricle following intraventricular administration of synthetic luteinizing hormone-releasing hormone (LH-RH): A scanning electron microscopic investigation

1977 • 22 citations

Early neuroradiologic evidence of degeneration in Menkes' disease

1997 • 22 citations

Menkes disease: a Golgi and electron microscopic study of the cerebellar cortex.

1988 • 20 citations

Animal Models of Menkes Disease

1999 • 20 citations

Ultrastructural and Morphometric Studies of Purkinje Cells of Brindled Mouse after Administration of Cupric Chloride

1985 • 20 citations

Distribution of Corticotropin‐Releasing Factor Binding Protein‐Immunoreactivity in the Rat Hypothalamus: Association With Corticotropin‐Releasing Factor‐, Urocortin 1‐ and Vimentin‐Immunoreactive Fibres

2005 • 20 citations

Cultured astrocytes express mRNA for peptidylglycine-α-amidating monooxygenase, a neuropeptide processing enzyme

1992 • 18 citations

Changes in the expression of calbindin D-28k in the gerbil hippocampus following seizure

2003 • 17 citations

Neuropathological study on cerebellum of macular mutant mouse heterozygote

1993 • 15 citations

Golgi study on macular mutant mouse after copper therapy

1988 • 14 citations

Cerebral lipid and protein abnormalities in Menkes' steely-hair disease.

1986 • 14 citations

Metallic prions

2004 • 13 citations

Are neurons of the arcuate nucleus necessary for pathfinding by GnRH fibers arising from third ventricular grafts?

1990 • 11 citations

Expression of the small conductance Ca 2+ -activated K + channel, SK3, in the olfactory ensheathing glial cells of rat brain

2003 • 9 citations

Immunocytochemical evidence for growth hormone-releasing hormone in the tanycytes of the median eminence of the rat.

2002 • 9 citations

Cell Type-Specific Metabolism of Peptidylglycine -Amidating Monooxygenase in Anterior Pituitary

2000 • 7 citations

Histochemical study of mitochondrial enzymes in cerebellar cortex of macular mutant mouse, a model of Menkes kinky hair disease

1994 • 7 citations

Fine structural changes in the cerebellar cortex in kinky hair disease.

1976 • 4 citations

The cellular localization of vasoactive intestinal peptide (VIP) in the mouse median eminence by immuno-electron microscopy

1996 • 3 citations