The Copper-transporting ATPases, Menkes and Wilson Disease Proteins, Have Distinct Roles in Adult and Developing Cerebellum

A sex-linked recessive disorder with retardation of growth, peculiar hair, and focal cerebral and cerebellar degeneration.

1962 • 839 citations

The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I)

1996 • 657 citations

Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking.

1996 • 623 citations

Aceruloplasminemia: molecular characterization of this disorder of iron metabolism.

1995 • 550 citations

Deficiency of Ceruloplasmin in Patients with Hepatolenticular Degeneration (Wilson's Disease)

1952 • 441 citations

Copper Binding in the Prion Protein

2004 • 380 citations

Ceruloplasmin Regulates Iron Levels in the CNS and Prevents Free Radical Injury

2002 • 362 citations

Intracellular Copper Transport in Mammals

2004 • 288 citations

Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion

2000 • 260 citations

Excitatory amino acid transporters: keeping up with glutamate

2002 • 240 citations

The Menkes copper transporter is required for the activation of tyrosinase

2000 • 213 citations

Null Mutation of the Murine ATP7B (Wilson Disease) Gene Results in Intracellular Copper Accumulation and Late-Onset Hepatic Nodular Transformation

1999 • 195 citations

Ceruloplasmin gene expression in the murine central nervous system.

1996 • 193 citations

Mechanisms of copper incorporation during the biosynthesis of human ceruloplasmin.

1991 • 188 citations

<scp>l</scp> -Serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons

2000 • 188 citations

Restoration of Holoceruloplasmin Synthesis in LEC Rat after Infusion of Recombinant Adenovirus Bearing WND cDNA

1998 • 167 citations

Aceruloplasminemia, an iron metabolic disorder

2003 • 134 citations

Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS

1996 • 131 citations

CNS demyelination associated with copper deficiency and hyperzincemia

2002 • 128 citations

A genetical analysis of thirty families with Wilson's disease (hepatolenticular degeneration)

1959 • 127 citations

The Regulation of Catalytic Activity of the Menkes Copper-translocating P-type ATPase

2001 • 126 citations

Functional Properties of the Copper-transporting ATPase ATP7B (The Wilson's Disease Protein) Expressed in Insect Cells

2002 • 105 citations

Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters

1997 • 93 citations

Mutation Analysis and Expression of the Mottled Gene in the Macular Mouse Model of Menkes Disease

1997 • 88 citations

Perspectives on copper biochemistry.

1986 • 84 citations

Supplying Copper to the Cuproenzyme Peptidylglycine α-Amidating Monooxygenase

2003 • 78 citations

Localization of Menkes gene expression in the mouse brain; its association with neurological manifestations in Menkes model mice

1996 • 50 citations

Mottled gene expression and copper distribution in the macular mouse, an animal model for Menkes disease

1998 • 25 citations

Selective transport of SC1 mRNA, encoding a putative extracellular matrix glycoprotein, during postnatal development of the rat cerebellum and retina

2000 • 19 citations