Interaction of human retinal RGS with G‐protein α‐subunits

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

1994 • 823 citations

The 2.2 Å crystal structure of transducin-α complexed with GTPγS

1993 • 788 citations

Structure of RGS4 Bound to AlF4−-Activated Giα1: Stabilization of the Transition State for GTP Hydrolysis

1997 • 770 citations

Rhodopsin content in the outer segment membranes of bovine and frog retinal rods

1974 • 730 citations

GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

1996 • 729 citations

EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins

1996 • 573 citations

GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GDP AIF−4

1994 • 564 citations

RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunits

1996 • 547 citations

RGS Proteins and Signaling by Heterotrimeric G Proteins

1997 • 522 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

1996 • 470 citations

RGS4 and GAIP are GTPase-activating proteins for G _qα and block activation of phospholipase Cβ by γ-thio-GTP-G _qα

1997 • 355 citations

The GTPase-activating Protein RGS4 Stabilizes the Transition State for Nucleotide Hydrolysis

1996 • 354 citations

RGS10 is a selective activator of Gαi GTPase activity

1996 • 354 citations

Characterization of transducin from bovine retinal rod outer segments. II. Evidence for distinct binding sites and conformational changes revealed by limited proteolysis with trypsin.

1983 • 331 citations

Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP

1992 • 324 citations

Molecular mechanism of visual transduction

1989 • 312 citations

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain.

1995 • 291 citations

Transduction mechanisms of vertebrate and invertebrate photoreceptors.

1994 • 286 citations

GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of Gα _i subunits

1996 • 166 citations

Characterization of a Novel Mammalian RGS Protein That Binds to Gα Proteins and Inhibits Pheromone Signaling in Yeast

1997 • 155 citations

Mapping of Effector Binding Sites of Transducin α-Subunit Using Gαt/Gαil Chimeras

1996 • 148 citations

Noncatalytic cGMP-binding sites of amphibian rod cGMP phosphodiesterase control interaction with its inhibitory gamma-subunits. A putative regulatory mechanism of the rod photoresponse.

1992 • 129 citations

RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling

1996 • 123 citations

Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase.

1994 • 115 citations

Stereochemistry of the guanyl nucleotide binding site of transducin probed by phosphorothioate analogs of GTP and GDP

1985 • 102 citations

Structural analysis of rod GTP-binding protein, Gt. Limited proteolytic digestion pattern of Gt with four proteases defines monoclonal antibody epitope

1991 • 93 citations

The core domain of a new retina specific RGS protein stimulates the GTPase activity of transducin in vitro

1997 • 90 citations

Interaction of Ethanol with Inducers of Glucose-regulated Stress Proteins

1996 • 52 citations

[50] Transducin and the cyclic GMP phosphodiesterase of retinal rod outer segments

1983 • 33 citations

GTP-dependent binding of Gi, Goand Gsto the γ-subunit of the effector of Gt

1994 • 5 citations