Immunotherapy for murine K1735 melanoma: Combinatorial use of recombinant adenovirus expressing CD40L and other immunomodulators

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Cancer statistics, 1998

1998 • 2,407 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1990 • 926 citations

The polypeptides of adenovirus

1968 • 879 citations

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

1998 • 586 citations

Therapy of tuberculosis in mice by DNA vaccination

1999 • 488 citations

Cloning and expression of murine IL-12.

1992 • 474 citations

Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy

1996 • 379 citations

Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.

1994 • 335 citations

Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now?

1994 • 245 citations

Inhibition of human B-cell lymphoma growth by CD40 stimulation

1994 • 232 citations

Phase I Study of Recombinant Human CD40 Ligand in Cancer Patients

2001 • 221 citations

Tumor antigens recognized by T lymphocytes

1997 • 153 citations

CD40 Ligand Induces an Antileukemia Immune Response In Vivo

1997 • 142 citations

Cancer vaccines: the interleukin 2 dosage effect.

1995 • 127 citations

Anti-Tumor Immunity Induced by in Vivo Adenovirus Vector-Mediated Expression of CD40 Ligand in Tumor Cells

1999 • 91 citations

Antitumor Effect of CD40 Ligand: Elicitation of Local and Systemic Antitumor Responses by IL-12 and B7

1998 • 90 citations

T‐helper‐ and accessory‐cell‐independent cytotoxic responses to human tumor cells transfected with A B7 retroviral vector

1994 • 79 citations

In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity

2000 • 75 citations

Therapeutic Vaccination for Cancer

2000 • 74 citations

Antitumor Responses Induced by Transgenic Expression of CD40 Ligand

1997 • 66 citations

Immunological Gene Therapy withex VivoGene-Modified Tumor Cells: A Critique and a Reappraisal

2000 • 64 citations

Gene transfer of GM-CSF, CD80 and CD154 cDNA enhances survival in a murine model of acute leukemia with persistence of a minimal residual disease

2000 • 44 citations

Comparative analysis of immunocritical melanoma markers in the mouse melanoma cell lines B16, K1735 and S91-M3

2001 • 38 citations

Adenovirus-mediated gene transfer into monocyte-derived macrophages of patients with X-linked chronic granulomatous disease: ex vivo correction of deficient respiratory burst

1997 • 38 citations

Expression of Co-Stimulatory Molecules by Tumor Cells Decreases Tumorigenicity but May Also Reduce Systemic Antitumor Immunity

1996 • 32 citations

Inhibition of murine melanoma growth by granulocyte-macrophage colony stimulating factor gene transfection is not haplotype specific

1998 • 6 citations

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