Immunohistochemical characterizationof nitric oxide synthase activity in squamous cell carcinoma of the head and neck

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Nitric oxide: an endogenous modulator of leukocyte adhesion.

1991 • 3,079 citations

Nitric oxide synthases in mammals

1994 • 2,762 citations

Neuronal NADPH diaphorase is a nitric oxide synthase.

1991 • 1,917 citations

Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells.

1989 • 1,747 citations

Biosynthesis of nitric oxide from l-arginine

1989 • 1,220 citations

An L-arginine/nitric oxide pathway present in human platelets regulates aggregation.

1990 • 1,209 citations

Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis

1994 • 1,065 citations

DNA damage and mutation in human cells exposed to nitric oxide in vitro.

1992 • 980 citations

Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.

1992 • 877 citations

Nitric Oxide Synthase in Human and Rat Lung: Immunocytochemical and Histochemical Localization

1993 • 825 citations

Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species.

1993 • 785 citations

Endogenous nitric oxide: physiology, pathology and clinical relevance

1991 • 766 citations

Macrophage Oxidation of L-Arginine to Nitric Oxide, Nitrite, and Nitrate

1989 • 681 citations

Source and fate of circulating citrulline

1981 • 457 citations

Nitric oxide synthase activity in human gynecological cancer.

1994 • 428 citations

Cytoprotective function of nitric oxide: Inactivation of superoxide radicals produced by human leukocytes

1991 • 368 citations

Molecular basis of "suppressor" macrophages. Arginine metabolism via the nitric oxide synthetase pathway.

1991 • 344 citations

Constitutive and inducible nitric oxide synthases incorporate molecular oxygen into both nitric oxide and citrulline.

1991 • 291 citations

Oxidative Stress Induces NFκB DNA Binding and Inducible NOS mRNA in Human Epithelial Cells

1994 • 263 citations

Enhanced Vascular Permeability in Solid Tumor Is Mediated by Nitric Oxide and Inhibited by Both New Nitric Oxide Scavenger and Nitric Oxide Synthase Inhibitor

1994 • 222 citations

NITRIC OXIDE—A NEW ENDOGENOUS IMMUNOMODULATOR

1993 • 198 citations

Four unlabeled antibody bridge techniques: a comparison.

1981 • 197 citations

Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells.

1994 • 195 citations

Macrophage arginine metabolism and the inhibition or stimulation of cancer.

1992 • 192 citations

Role of nitric oxide in lysis of tumor cells by cytokine-activated endothelial cells.

1991 • 192 citations

Citrulline synthesis in rat tissues

1961 • 189 citations

Human colorectal adenocarcinoma cells: differential nitric oxide synthesis determines their ability to aggregate platelets.

1991 • 182 citations

Inhibitors of nitric oxide synthase selectively reduce flow in tumour‐associated neovasculature

1992 • 179 citations

Nitric oxide involvement in tumor-induced immunosuppression.

1994 • 171 citations

The Discovery of Nitric Oxide in the Vessel Wall

1993 • 150 citations

Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cells via nitric oxide release.

1993 • 137 citations

Time‐dependent enhancement or inhibition of endotoxin‐induced vascular injury in rat intestine by nitric oxide synthase inhibitors

1994 • 137 citations

Liver fluke infection and cholangiocarcinoma: model of endogenous nitric oxide and extragastric nitrosation in human carcinogenesis

1994 • 137 citations

Cytokines and Lipopolysaccharide Induce Nitric Oxide Synthase in Cultured Rat Pulmonary Artery Smooth Muscle

1992 • 131 citations

Hormone-induced biosynthesis of endothelium-derived relaxing factor/nitric oxide-like material in N1E-115 neuroblastoma cells requires calcium and calmodulin.

1990 • 111 citations

Citrulline in the rat brain: Immunohistochemistry and coexistence with NADPH-diaphorase

1991 • 92 citations

Isolation of a nitric oxide inhibitor from mammary tumor cells and its characterization as phosphatidyl serine.

1994 • 79 citations

Nitric oxide modulates vascular permeability in the rat coronary circulation

1993 • 75 citations

Cellular models of macrophage tumoricidal effector mechanisms in vitro. Characterization of cytolytic responses to tumor necrosis factor and nitric oxide pathways in vitro.

1991 • 72 citations

The L-Arginine Dependent Effector Mechanism Is Induced in Murine Adenocarcinoma Cells by Culture Supernatant From Cytotoxic Activated Macrophages

1988 • 63 citations

Induction of nitric oxide synthase in the neo‐vasculature of experimental tumours in mice

1993 • 59 citations

Bovine bronchial epithelial cells metabolize L-arginine to L-citrulline: Possible role of nitric oxide synthase

1993 • 55 citations

Esophageal Epithelial Defense Against Acid Injury

1991 • 47 citations

Involvement of Nitric Oxide in Tumor Cell Adhesion to Cytokine-Activated Endothelial Cells

1992 • 33 citations

PMN adhesion and extravasation as a paradigm for tumor cell dissemination

1991 • 28 citations

Differences between preneoplastic cells, neoplastic cells and their normal counterparts

1988 • 17 citations