Time‐dependent enhancement or inhibition of endotoxin‐induced vascular injury in rat intestine by nitric oxide synthase inhibitors

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Nitric oxide: an endogenous modulator of leukocyte adhesion.

1991 • 3,079 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Evaluation of High-Sensitivity C-Reactive Protein and Serum Lipid Profile in Southeastern Nigerian Women with Pre-Eclampsia

2015 • 2,005 citations

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

1990 • 1,869 citations

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1988 • 1,622 citations

ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

1987 • 1,450 citations

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1987 • 1,171 citations

Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells.

1990 • 1,117 citations

Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

1991 • 873 citations

Endothelial cell interactions with granulocytes: tethering and signaling molecules

1992 • 773 citations

Role of neutrophils in ischemia-reperfusion-induced microvascular injury

1987 • 704 citations

Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells

1990 • 700 citations

Widespread tissue distribution, species distribution and changes in activity of Ca²⁺‐dependent and Ca²⁺‐independent nitric oxide synthases

1991 • 645 citations

Protective and pathological roles of nitric oxide in endotoxin shock

1992 • 594 citations

Nitric oxide modulates microvascular permeability

1992 • 564 citations

Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process

1990 • 563 citations

Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis

1990 • 562 citations

Modulation of acute inflammation by endogenous nitric oxide

1992 • 543 citations

Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo

1990 • 536 citations

Synthesis of nitric oxide from <scp>l</scp>-arginine by neutrophils. Release and interaction with superoxide anion

1989 • 529 citations

Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide.

1989 • 464 citations

Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat

1990 • 454 citations

Neutrophil-mediated mucosal injury

1988 • 445 citations

Inhibition of nitric oxide synthesis in septic shock: how much is beneficial?

1991 • 409 citations

Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat

1990 • 389 citations

Leukocyte adherence to venular endothelium during ischemia-reperfusion

1989 • 381 citations

Role of nitric oxide in maintaining vascular integrity in endotoxin‐induced acute intestinal damage in the rat

1990 • 369 citations

Ischemia-induced vascular changes: role of xanthine oxidase and hydroxyl radicals

1983 • 318 citations

Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor.

1989 • 311 citations

Generation of nitric oxide by human neutrophils

1989 • 298 citations

The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat

1993 • 295 citations

A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit

1991 • 284 citations

Formation and release of nitric oxide from human neutrophils and HL‐60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B₄

1989 • 244 citations

The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids

1992 • 233 citations

Role of platelet-activating factor in ischemia/reperfusion-induced leukocyte adherence

1990 • 226 citations

Internalization of fluorescent vasotocin-receptor agonist and antagonist in the toad bladder

1990 • 211 citations

Evidence that endogenous nitric oxide modulates oedema formation induced by substance P

1990 • 201 citations

CORONARY ARTERY INFUSION OF NEUROPEPTIDE Y IN PATIENTS WITH ANGINA PECTORIS

1987 • 196 citations

Ethanol-induced injury to the rat gastric mucosa

1990 • 189 citations

Role of neutrophils in hemorrhagic shock-induced gastric mucosal injury in the rat

1987 • 161 citations

Interaction of neutrophils with vascular smooth muscle: identification of a neutrophil-derived relaxing factor.

1988 • 160 citations

Protective effect of S-nitroso-N-acetyl-penicillamine in endotoxin-induced acute intestinal damage in the rat

1990 • 133 citations

Platelet-activating factor-induced microvascular dysfunction: role of adherent leukocytes

1990 • 105 citations

Oxygen radicals: effects on intestinal vascular permeability

1984 • 99 citations

Endotoxin‐induced vasodilatation in anaesthetized rat skin involves nitric oxide and prostaglandin synthesis

1992 • 54 citations

The biology of nitric oxide. 1. Physiological and clinical aspects

1993 • 8 citations